Inventors:
Jennifer A. Dumont - Groton MA, US
Susan Low - Pepperill MA, US
Alan J. Bitonti - Acton MA, US
Glenn Pierce - Rancho Santa Fe CA, US
Alvin Luk - Boston MA, US
Haiyan Jiang - Belmont MA, US
Byron McKinney - San Diego CA, US
Matt Ottmer - Newton MA, US
Jurg Sommer - Wayland MA, US
Karen Nugent - Princes Risborough, GB
Lian Li - Lexington MA, US
Robert Peters - Needham MA, US
Assignee:
BIOGEN IDEC HEMOPHILIA INC. - Waltham MA
International Classification:
C07K 14/755
C07K 16/46
Abstract:
The present invention provides methods of administering Factor VIII; methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.