US Patent:
20220265780, Aug 25, 2022
Inventors:
- Waltham MA, US
Susan LOW - Pepperill MA, US
Alan J. BITONTI - Acton MA, US
Glenn PIERCE - Rancho Santa Fe CA, US
Alvin LUK - Boston MA, US
Haiyan JIANG - Belmont MA, US
Byron MCKINNEY - San Diego CA, US
Matt OTTMER - Newton MA, US
Jurg SOMMER - Wayland MA, US
Karen NUGENT - Princes Risborough, GB
Lian LI - Lexington MA, US
Robert PETERS - Needham MA, US
International Classification:
A61K 38/37
A61K 47/64
A61K 47/68
C07K 14/755
C07K 16/46
Abstract:
The present invention provides methods of administering Factor VIII; methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.