Li M Liu

6569638, May 27, 2003

Mar 3, 2000

09/517734

I. Bernard Weinstein - Englewood NJ
W. Joseph Thompson - Doylestown PA
Jae-Won Soh - Cliffside Park NJ
Li Liu - Ambler PA
Han Li - Yardley PA

Cell Pathways, Inc - Horsham PA

C12Q 148

435 15, 435 692, 435184

This invention provides a method to identify compounds potentially useful for the treatment and prevention of neoplasia in mammals. The phosphodiesterase inhibitory activity of a compound is determined along with its ability to elevate JNK kinase activity. Growth inhibitory and apoptosis inducing effects on cultured tumor cells are also determined. Compounds that exhibit phosphodiesterase inhibition, an ability to elevate JNK kinase activity, growth inhibition and apoptosis induction are desirable for the treatment of neoplasia.

8035711, Oct 11, 2011

May 22, 2008

12/125466

Li Liu - Cortland NY, US
Jeffrey Jon Zarnowski - McGraw NY, US
Ketan Vrajlal Karia - Cortland NY, US
Thomas Poonnen - Cortland NY, US
Michael Eugene Joyner - McGraw NY, US

Panavision Imaging, LLC - Homer NY

H04N 9/083

348277

Improving the dynamic range of captured images is disclosed by using sub-pixel arrays to capture light at different exposures and generate color pixel outputs for an image in a single frame. Each sub-pixel array can include multiple sub-pixels. The sub-pixels that make up a sub-pixel array can include red (R) sub-pixels, green (G) sub-pixels, blue (B) sub-pixels, and in some embodiments, clear sub-pixels. Those sub-pixel arrays having clear sub-pixels effectively have a higher exposure level and can capture low-light scenes (for dark areas) better than those sub-pixel arrays without clear sub-pixels. Each sub-pixel array can produce a color pixel output that is a combination of the outputs of the sub-pixels in the sub-pixel array. Each sub-pixel in a sub-pixel array can have the same exposure time, or in some embodiments, individual sub-pixels within a sub-pixel array can have different exposure times to improve the overall dynamic range even more.

8169517, May 1, 2012

Oct 16, 2007

11/974813

Thomas Poonnen - Cortland NY, US
Jeffrey J. Zarnowski - McGraw NY, US
Li Liu - Cortland NY, US
Michael Joyner - McGraw NY, US
Ketan V. Karia - Cortland NY, US

Panavision Imaging LLC - Homer NY

H04N 5/335
H04N 3/14

348294, 348302

A solid state imager converts analog pixel values to digital form on an arrayed per-column basis. An N-bit counter supplies an N-bit DAC to produce an analog ramp output with a level that varies corresponding to the contents of the counter. A latch/counter or equivalent is associated with each respective column. A clock supplies clock signal(s) to the counter elements. When the analog ramp equals the pixel value for that column, the latch/counter latches the value. The black level can be pre-set in the latch/counter or can be subtracted separately to reduce fixed pattern noise. The pixels can be oversampled for some number of times, e. g. , n=16, to reduce the thermal noise of the sensors. Also, two or more pixels sharing a common sense node may be binned together, and two (or more) pixels having different integration times may be combined to obtain an output signal with enhanced dynamic range.

20090290052, Nov 26, 2009

May 23, 2008

12/126347

Li Liu - Cortland NY, US
Jeffrey Jon Zarnowski - McGraw NY, US
Ketan Vrajlal Karia - Cortland NY, US
Thomas Poonnen - Cortland NY, US
Michael Eugene Joyner - McGraw NY, US

H04N 9/04

348277, 348E09002

The use of a Bayer pattern array in digital image sensors to enhance the dynamic range of the sensors is disclosed. Each Bayer pattern in the array can include three different pixels having a first exposure, and a fourth pixel (which is the same color as one of the other pixels in the array) having a second exposure. The dynamic range of the Bayer pattern array can be enhanced by using different exposure times for the pixels. Each pixel can capture only one channel (i.e. either red (R), green (G) or blue (B) light). Interpolation of neighboring pixels, including those having different exposure times, can enable the pixels in the Bayer pattern array to generate missing color information and effectively become a color pixel, and can allow the Bayer pattern array to have a higher dynamic range.