Leo M Sreebny

55101224, Apr 23, 1996

Sep 28, 1994

8/314515

Leo M. Sreebny - East Setauket NY
Steven S. Schwartz - Melville NY
Allen G. Meek - Poquott NY

The Research Foundation of State University of New York - Albany NY

A61K 728

424537

The preparation of a saliva composition substantially viable for therapeutic use in saliva-deficient individuals involves exogenously treating saliva to inactivate microorganisms by contacting with chlorhexidine or ionizing radiation. Pharmaceutically active agents may be added to the saliva composition.

48205060, Apr 11, 1989

May 1, 1987

7/045618

Israel Kleinberg - Smithtown NY
Leo M. Sreebny - East Setauket NY

Research Foundation, State University of New York - Albany NY

A01N 2506

424 40

An aqueous liquid for promoting the production of human saliva in situ comprises: (a) about 2 to 3 wgt percent organic acidulent such as citric, malic, or ascorbic acid; (b) about 0. 5 to 2. 5 wgt percent of a natural, food-grade sweetener such as fructose or 0. 05 to 0. 5 wgt percent of a synthetic sweetener such as aspartame or saccharin; and (c) a saturated calcium phosphate solution. The preferred form of the aqueous liquid is a metered, hand-actuated, aerosol spray of about 0. 15 ml. per actuation. By employing the aqueous liquid of the invention the production of saliva is tripled, thus alleviating the many symptoms of xerostomia no matter what its cause.

50781294, Jan 7, 1992

Mar 8, 1990

7/490368

Israel Kleinberg - Smithtown NY
Leo M. Sreebny - East Setauket NY

Research Foundation of State University of New York - Albany NY

A61M 1100

12820014

A dispenser for an aqueous sialogogue for the mouth comprises: a) a reservoir for the aqueous sialogogue solution; b) passage means leading from the reservoir to a spray head; and c) a plurality of orifices in the spray head, whereby actuating the spray head causes a plurality of streams to be directed to those regions of the mouth most dry in a reniform pattern. Preferably a metered amount of sialogogue is delivered by an actuating means selected from the group consisting of a hand-activating spray pump, a bulb-activated spray pump or an aerosol propellant. The sialogogue solution comprises: a) from about 2 to about 3 wgt % of food-grade organic acidulant; b) a food-grade sweetener benign to stomic microflora; and c) a saturated calcium phosphate solution, whereby the production of human saliva is promoted in situ without corrosion, infection, or dissolution of human teeth.

47682388, Sep 6, 1988

May 4, 1987

7/046837

Israel Kleinberg - Smithtown NY
Leo M. Sreebny - East Setauket NY

Interstate Drug Exchange - Amityville NY

A61J 1900

4258

This patent relates to a bifurcated vessel for the collection of saliva comprising: (a) a receptacle open at one end and divided into two chambers for holding liquid; (b) an open edge portion angularly disposed integral with one of said chambers to constitute a flared funnel to said chamber; and (c) a second open edge portion angularly disposed to and integral with the other of said two chambers to constitute a flared funnel.