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Lance H Leopold

from Dresher, PA
Age ~63
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Also known as:
Lance Dr Leopold, Lance Howard Leopold, Lance H Leopol, Lance Leopo
Phone and address:
1441 Catlin Way, Dresher, PA 19025
(215) 641-9255
Related to:
Robert Leopold, 59Leonore Leopold, 85Joseph W Brochu, 40Marion Brochu, 99Nancy G Leopold, 64
Connected to:
Abigail M Leopold, 30Alexander M Leopold, 55Autumn O Leopold, 50Brenda L Leopold, 64Christina M Leopold, 48Crystal L Leopold, 64Elaine L Leopold, 53Fred J Leopold, 89Georges U Leopold, 70Guy E Leopold, 65

Lance Leopold Phones & Addresses

  • 1441 Catlin Way, Dresher, PA 19025 (215) 641-9255
  • Philadelphia, PA

Work

Company: Temple University Hospital Address: 3401 North Broad Street, Philadelphia, PA 19140

Education

School / High School: Temple University 1987

Languages

English

Awards

Healthgrades Honor Roll

Ranks

Certificate: Hematology, 1994

Emails

l***[email protected]

Specialities

Hematology • Medical Oncology • Oncology

Professional Records

Medicine Doctors

Lance Leopold Photo 1

Dr. Lance Leopold, Dresher PA - MD (Doctor of Medicine)

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Specialties:
Hematology
Medical Oncology
Oncology
Address:
1441 Catlin Way, Dresher, PA 19025
(866) 305-6063 (Fax)
Certifications:
Hematology, 1994
Internal Medicine, 2001
Medical Oncology, 1993
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
1441 Catlin Way, Dresher, PA 19025

Temple University Hospital
3401 North Broad Street, Philadelphia, PA 19140
Education:
Medical School
Temple University
Graduated: 1987
Medical School
Temple U
Graduated: 1987
Medical School
Temple & Fox Chase
Graduated: 1987
Lance Leopold Photo 2

Lance Howard Leopold, Philadelphia PA

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Specialties:
Internal Medicine
Hematology
Hematology & Oncology
Medical Oncology
Work:
Temple Gyn. Oncology Associates
3401 N Broad St, Philadelphia, PA 19140
Education:
Temple University Physicians (1987)

License Records

Lance Howard Leopold

License #:
MT019156T - Expired
Category:
Medicine
Type:
Graduate Medical Trainee

Lance Howard Leopold

Address:
Dresher, PA 19025
License #:
MD044489E - Expired
Category:
Medicine
Type:
Medical Physician and Surgeon

Business Records

Name / Title
Company / Classification
Phones & Addresses
Lance Howard Leopold
Lance Leopold MD
Internist
3401 N Broad St, Philadelphia, PA 19140
(215) 707-4000

Publications

Us Patents

Combination Therapy For The Treatment Of Acute Leukemia And Myelodysplastic Syndrome

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US Patent:
7727968, Jun 1, 2010
Filed:
Jun 11, 2007
Appl. No.:
11/811626
Inventors:
Jay Marshall Feingold - Wynnewood PA, US
Matthew L. Sherman - Newton MA, US
Lance H. Leopold - Dresher PA, US
Mark Berger - Merion Station PA, US
Assignee:
Wyeth LLC - Madison NJ
International Classification:
A61K 31/70
US Classification:
514 34, 4241811, 514 45, 514 49
Abstract:
Methods of treatment and pharmaceutical combinations are provided for the treatment of acute leukemia, such as acute myelogenous leukemia, and myelodysplastic syndrome. The methods of treatment and pharmaceutical combinations employ an anti-CD33 cytotoxic conjugate in combination with at least one compound selected from the group consisting of an anthracycline and a pyrimidine or purine nucleoside analog. Preferred methods of treatment and pharmaceutical combinations employ gemtuzumab ozogamicin, daunorubicin, and cytarabine.

Pulsatile Dosing Of Gossypol For Treatment Of Disease

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US Patent:
20090010878, Jan 8, 2009
Filed:
Jun 2, 2008
Appl. No.:
12/155327
Inventors:
Jon T. Holmlund - Carlsbad CA, US
Mel Sorensen - Malvern PA, US
Lance Leopold - Dresher PA, US
Dajun Yang - Rockville MD, US
Assignee:
Ascenta Therapeutics, Inc. - Malvern PA
International Classification:
A61K 31/11
A61K 38/20
A61P 35/00
US Classification:
424 852, 514700
Abstract:
This invention relates to pulsatile dose administration of gossypol or pharmaceutical compositions thereof for treating diseases, disorders and conditions responsive to gossypol, inhibiting the activity of anti-apoptotic Bcl-2 family proteins, inducing apoptosis in cells and increasing the sensitivity of cells to inducers of apoptosis.

Pulsatile Dosing Of Gossypol For Treatment Of Disease

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US Patent:
20090175869, Jul 9, 2009
Filed:
Dec 10, 2008
Appl. No.:
12/332039
Inventors:
Jon T. Holmlund - Carlsbad CA, US
Mel Sorensen - Malvern PA, US
Lance Leopold - Dresher PA, US
Dajun Yang - Rockville MD, US
Assignee:
Ascenta Therapeutics, Inc. - Malvern PA
International Classification:
A61K 39/395
A61K 31/12
A61K 31/337
A61K 31/454
A61K 33/24
A61K 31/282
A61K 31/517
A61K 31/437
A61P 35/00
US Classification:
4241381, 514681, 514449, 514323, 424649, 514492, 5142664, 514283
Abstract:
This invention relates to pulsatile dose administration of gossypol, a gossypol-related compound or pharmaceutical compositions thereof for treating diseases, disorders and conditions responsive to gossypol or gossypol-related compound, inhibiting the activity of anti-apoptotic Bcl-2 family proteins, inducing apoptosis in cells and increasing the sensitivity of cells to inducers of apoptosis.

Pulsatile Dosing Of Gossypol For Treatment Of Disease

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US Patent:
20100189683, Jul 29, 2010
Filed:
Dec 10, 2009
Appl. No.:
12/635481
Inventors:
Jon T. Holmlund - Carlsbad CA, US
Mel Sorensen - Malvern PA, US
Lance Leopold - Dresher PA, US
Dajun Yang - Rockville MD, US
Assignee:
Ascenta Therapeutics, Inc. - Malvern PA
International Classification:
A61K 38/20
A61K 31/11
A61K 38/00
A61K 39/395
A61K 31/203
A61K 31/519
A61K 31/53
A61K 31/661
A61K 31/45
A61K 31/4196
A61K 31/285
A61K 38/50
A61K 31/7036
A61K 31/52
A61K 39/07
A61K 31/192
A61K 31/167
A61K 38/14
A61K 31/69
A61K 31/255
A61K 31/4152
A61K 31/505
A61K 31/282
A61K 33/24
A61K 31/7068
A61K 38/16
A61K 31/573
A61K 38/21
A61K 33/12
A61K 31/337
A61K 31/437
A61K 31/517
A61K 31/454
A61P 35/00
US Classification:
424 852, 514700, 514 2, 4241331, 514557, 5142621, 514245, 514114, 514328, 514383, 424623, 424 946, 514 43, 5142632, 4241841, 514569, 514618, 514 8, 514 64, 514517, 514404, 514269, 514492, 424649, 514 49, 514 12, 514179, 424 857, 424683, 514449, 514283, 5142664, 514177, 514323, 514285
Abstract:
This invention relates to pulsatile dose administration of gossypol or pharmaceutical compositions thereof for treating diseases, disorders and conditions responsive to gossypol, inhibiting the activity of anti-apoptotic Bcl-2 family proteins, inducing apoptosis in cells and increasing the sensitivity of cells to inducers of apoptosis.

Spiro-Oxindole Mdm2 Antagonists

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US Patent:
20120122947, May 17, 2012
Filed:
Nov 11, 2011
Appl. No.:
13/294315
Inventors:
Shaomeng Wang - Saline MI, US
Yujun Zhao - Ann Arbor MI, US
Wei Sun - Ann Arbor MI, US
Sanjeev Kumar - Ann Arbor MI, US
Lance Leopold - Dresher PA, US
Laurent Debussche - Paris, FR
Cedric Barriere - Paris, FR
Jean-Christophe Carry - Paris, FR
Kwame Amaning - Paris, FR
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
SANOFI - Paris
ASCENTA THERAPEUTICS, INC. - Malvern PA
International Classification:
A61K 31/407
A61P 35/00
A61P 35/02
C07D 487/10
US Classification:
514409, 548410
Abstract:
Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.

Multi-Unit Ribozyme Inhibition Of Oncogene Gene Expression

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US Patent:
56353855, Jun 3, 1997
Filed:
Sep 15, 1993
Appl. No.:
8/122795
Inventors:
Lance H. Leopold - Philadelphia PA
Scott K. Shore - Ardmore PA
Moole V. R. Reddy - Upper Darby PA
E. Premkumar Reddy - Villanova PA
Assignee:
Temple University-of the Commonwealth System of Higher Education - Philadelphia PA
International Classification:
C12N 508
C12N 516
C12N 1585
C07H 2102
US Classification:
435325
Abstract:
A novel multi-unit ribozyme is provided which is capable of selectively cleaving the mRNA transcript of a hybrid oncogene resulting from a chromosomal translocation. Specialized delivery vehicles such as liposomes, and growth factor conjugates for cellular uptake by receptor-mediated endocytosis, are also described. The multi-unit ribozyme is used for the treatment of neoplasms characterized by expression of the oncogene. In one embodiment, a multi-unit ribozyme is provided which cleaves the mRNA transcript of Philadelphia chromosome-positive cells, thereby blocking production of the tumorigenic p210. sup. bcr-abl fusion protein.

Spiro-Oxindole Mdm2 Antagonists

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US Patent:
20140148494, May 29, 2014
Filed:
Jan 31, 2014
Appl. No.:
14/170101
Inventors:
- Ann Arbor MI, US
- Paris, FR
- Wilmington DE, US
Sanjeev Kumar - Ann Arbor MI, US
Lance Leopold - Dresher PA, US
Laurent Debussche - Paris, FR
Cedric Barriere - Paris, FR
Jean-Christophe Carry - Paris, FR
Kwame Amaning - Paris, FR
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
Sanofi - Paris
Ascenta Licensing Corporation - Wilmington DE
International Classification:
C07D 487/10
A61K 31/407
A61N 5/10
A61K 45/06
US Classification:
514409, 548410, 600 1
Abstract:
Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.
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Lance H Leopold from Dresher, PA, age ~63 Get Report