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Kyoichi A Watanabe

from Stone Mountain, GA
Age ~89
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Also known as:
Kyoichi Dr Watanabe, Kyoichi S Watanabe, Kiyoko A Watanabe, Katharine A Watanabe, Kyoichi A Watanbe, Ka Watanabe, I Watanabe
Phone and address:
5765 Redcoat Run, Stone Mountain, GA 30087
(770) 414-1721
Related to:
Thea A Watanabe, 41Kate A Watanabe, 60Paula J Roberts, 72Cesare MastropietroMarcello M Mastropietro, 71Charles J Roberts, 73Kaoru Watanabe, 55Krystyna B LesiakKiyoko A Watanabe, 87Dario R Mastropietro, 66Daniel W Bedford, 56Santina MastropietroRosemary Amendolia, 68Cesare MastropietroEdward R RobertsCesar J Mastropietro, 61Tom WatanabeMichelle A Watanabe, 52
Connected to:
Akinori Watanabe, 51Akira Watanabe, 53Ami Watanabe, 87Atsuko Watanabe, 48Brian F Watanabe, 54Carl P Watanabe, 68Carlos L Watanabe, 49Charles P Watanabe, 62Cynthia A Watanabe, 60Donald Y Watanabe, 69

Kyoichi Watanabe Phones & Addresses

  • 5765 Redcoat Run, Stone Mtn, GA 30087 (770) 414-1721
  • Stone Mountain, GA
  • Harrison, NY
  • Buchanan, NY
  • Mamaroneck, NY
  • Rye Brook, NY
  • Rye, NY
  • Bronxville, NY
  • New York, NY
  • Westchester, NY
  • Plano, TX

Publications

Us Patents

Processes For Preparing 1,3-Dioxolane Nucleosides

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US Patent:
6855821, Feb 15, 2005
Filed:
Aug 6, 2003
Appl. No.:
10/635971
Inventors:
Jinfa Du - Lilburn GA, US
Kyoichi A. Watanabe - Stone Mountain GA, US
Assignee:
Pharmasset, Ltd. - Tucker GA
International Classification:
C07D473/00
US Classification:
544265, 544276, 544277
Abstract:
Disclosed are novel processes for preparing 1,3-dioxolane nucleosides of general formula I and II: wherein B is a purine or pyrimidine base or an analog or derivative thereof. The invention also provides intermediates for use in the preparation of these compounds.

N4-Acylcytosine-1,3-Dioxolane Nucleosides For Treatment Of Viral Infections

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US Patent:
6908924, Jun 21, 2005
Filed:
Dec 16, 2002
Appl. No.:
10/320350
Inventors:
Kyoichi A. Watanabe - Stone Mountain GA, US
Junxing Shi - Duluth GA, US
Michael J. Otto - Lilburn GA, US
Assignee:
Pharmasset, Inc. - Tucker GA
International Classification:
C07D407/04
A61K031/506
A61P031/18
A61P031/22
US Classification:
514272, 544243, 544320, 544321
Abstract:
The present invention is directed to a compound, method and composition of treating or preventing viral infections, in particular, human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections, in human patients or other animal hosts, comprising the administration of N-acylcytosine-1,3-dioxolane and pharmaceutically acceptable salts, prodrugs, and other derivatives thereof.

3′-Or 2′-Hydroxymethyl Substituted Nucleoside Derivatives For Treatment Of Hepatitis Virus Infections

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US Patent:
7094770, Aug 22, 2006
Filed:
Apr 13, 2001
Appl. No.:
09/834596
Inventors:
Kyoichi A. Watanabe - Stone Mountain GA, US
S. Balakrishna Pai - Chamblee GA, US
Assignee:
Pharmasset, Ltd. - St. Michael
International Classification:
A01N 43/04
A61K 31/70
US Classification:
514 49, 514 50, 514 51, 514 52
Abstract:
The present invention relates to a composition for and a method of treating hepatitis B virus (HBV) infection, hepatitis C virus (HCV) infection, hepatitis D virus (HDV) infection or a proliferative disorder in a patient using an effective amount of a compound selected from the group consisting of formulas [I]–[IV] below and mixtures of two or more thereof:.

N-Acylcytosine Nucleosides For Treatment Of Viral Infections

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US Patent:
7105527, Sep 12, 2006
Filed:
Dec 13, 2002
Appl. No.:
10/318511
Inventors:
Michael J. Otto - Lilburn GA, US
Junxing Shi - Duluth GA, US
Kyoichi A. Watanabe - Stone Mountain GA, US
International Classification:
C07D 239/47
A61K 31/513
A61K 31/7072
A61P 31/18
US Classification:
514269, 544318, 536 268
Abstract:
The present invention is directed to a method and composition of treating or preventing viral infections, in particular, human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections, in human patients or other animal hosts, comprising the administration of N-acyl-2′,3′-dideoxy-5-fluorocytidine or N-acyl-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine, and pharmaceutically acceptable salts, prodrugs, and other derivatives thereof.

N4-Acylcytosine-1,3-Dioxolane Nucleosides For Treatment Of Viral Infections

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US Patent:
RE42015, Dec 28, 2010
Filed:
Jun 21, 2007
Appl. No.:
11/821076
Inventors:
Kyoichi A. Watanabe - Stone Mountain GA, US
Junxing Shi - Duluth GA, US
Michael J. Otto - East Windsor NJ, US
Assignee:
Pharmasset, Inc. - Princeton NJ
International Classification:
C07D 407/04
A61K 31/506
A61P 31/18
A61P 31/22
US Classification:
514272, 544242, 544320, 544321
Abstract:
The present invention is directed to a compound, method and composition of treating or preventing viral infections, in particular, human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections, in human patients or other animal hosts, comprising the administration of N-acylcytosine-1,3-dioxolane and pharmaceutically acceptable salts, prodrugs, and other derivatives thereof.

Compounds With The Bicyclo[4.2.1]Nonane System For The Treatment Of Infections

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US Patent:
8093380, Jan 10, 2012
Filed:
Aug 1, 2003
Appl. No.:
10/632997
Inventors:
Peiyuan Wang - Lilburn GA, US
Lieven J. Stuyver - Snellville GA, US
Kyoichi A. Watanabe - Stone Mountain GA, US
Abdalla Hassan - Chamblee GA, US
Laurent Hollecker - Atlanta GA, US
Assignee:
Pharmasset, Inc. - Tucker GA
International Classification:
C07D 403/00
C07D 405/00
US Classification:
540480
Abstract:
The disclosed invention is a bicyclo[4. 2. 1]nonane and its pharmaceutically acceptable salt or prodrug, and its composition and method of use to treat Flaviviridae (Hepacivirus, Flavivirus, and Pestivirus) infections in a host, including animals, and especially humans.

N-Acylcytosine Nucleosides For Treatment Of Viral Infections

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US Patent:
8114997, Feb 14, 2012
Filed:
Jan 4, 2008
Appl. No.:
11/969427
Inventors:
Michael J. Otto - Lilburn GA, US
Junxing Shi - Duluth GA, US
Kyoichi A. Watanabe - Stone Mountain GA, US
Assignee:
Pharmasset, Inc. - Princeton NJ
International Classification:
C07D 239/47
A61K 31/513
A61K 31/7072
A61P 31/18
US Classification:
544318, 514269, 514 49, 536 268
Abstract:
The present invention is directed to a method and composition of treating or preventing viral infections, in particular, human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections, in human patients or other animal hosts, comprising the administration of N. sup. 4-acyl-2′,3′-dideoxy-5-fluorocytidine or N. sup. 4-acyl-2′,3′-didehyd-ro-2′,3′-dideoxy-5-fluorocytidine, and pharmaceutically acceptable salts, prodrugs, and other derivatives thereof.

Modified Nucleosides For The Treatment Of Viral Infections And Abnormal Cellular Proliferation

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US Patent:
20030087873, May 8, 2003
Filed:
Oct 18, 2001
Appl. No.:
10/045292
Inventors:
Lieven Stuyver - Snellville GA, US
Kyoichi Watanabe - Stone Mountain GA, US
International Classification:
A61K031/7076
A61K031/675
A61K031/519
A61K031/513
US Classification:
514/045000, 514/049000, 514/081000, 514/086000, 514/261100, 514/263230, 514/269000, 514/303000
Abstract:
The disclosed invention is a composition for and a method of treating a Flaviviridae (including BVDV and HCV), Orthomyxoviridae (including Influenza A and B) or Paramyxoviridae (including RSV) infection, or conditions related to abnormal cellular proliferation, in a host, including animals, and especially humans, using a nucleoside of general formula (I)-(XXIII) or its pharmaceutically acceptable salt or prodrug. This invention also provides an effective process to quantify the viral load, and in particular BVDV, HCV or West Nile Virus load, in a host, using real-time polymerase chain reaction (“RT-PCR”). Additionally, the invention discloses probe molecules that can fluoresce proportionally to the amount of virus present in a sample.
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Kyoichi A Watanabe from Stone Mountain, GA, age ~89 Get Report