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Kyle M Botsch

from La Mesa, CA
Age ~40
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Also known as:
Kyle Matthew Botsch
Phone and address:
5307 Swarthmore St, La Mesa, CA 91942
Related to:
Christopher R Botsch, 38William Botsch, 42William R Botsch, 70Sarah A Mcguinn, 43Debra L Botsch, 70
Connected to:
Deborah E Botsch, 60Maria Botsch, 87Mary L Botsch, 65Bill C Botsford, 77Brooke M Botsford, 36Courtney L Botsford, 60Dennis A Botsford, 66Derek J Botsford, 39Diane Botsford, 72Don R Botsford, 69

Kyle Botsch Phones & Addresses

  • 5307 Swarthmore St, La Mesa, CA 91942
  • 3347 Clairemont Mesa Blvd, San Diego, CA 92117
  • Morro Bay, CA
  • Cayucos, CA
  • 5998 Alcala Park #8048, San Diego, CA 92110 (619) 849-5127

Emails

x***r@msn.com

Resumes

Resumes

Kyle Botsch Photo 1

Senior Research Associate At Sapphire Energy

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Location:
1500 Hwy #9, Columbus, NM
Industry:
Biotechnology
Work:
Sapphire Energy
Senior Research Associate at Sapphire Energy
Skills:
Molecular Biology
Metabolic Engineering
Kyle Botsch Photo 2

Lead Scientist- Molecular Biology

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Location:
San Diego, CA
Industry:
Biotechnology
Work:
Renew Biopharma, Inc.
Lead Scientist- Molecular Biology
Epic Sciences Jul 2015 - Mar 2017
Scientist- Assay Development
Sapphire Energy Dec 2007 - Feb 2015
Senior Research Associate
Education:
University of San Diego 2002 - 2007
Bachelors, Biochemistry
Skills:
Qpcr
Taqman Assay Design and Optimization
Synthetic Biology
Molecular Cloning
Protein Assays
Protein Engineering
Western Blotting
Protein Expression
Protein Purification
Pcr
Life Sciences
Dna
Cell Culture
Biochemistry
Assay Development
Cell Biology
High Throughput Screening
Biotechnology
Microsoft Word
Microsoft Office
Microbiology
Molecular Biology
Laboratory
Lasergene Dna Software
Dna Electrophoresis
Biofuels
Genetics
Immunofluorescence
Flow Cytometry
Statistics
Ivd
Cancer Research
Medical Diagnostics
Molecular Diagnostics
Antibodies
Interests:
Science and Technology
Environment

Publications

Us Patents

System For Transformation Of The Chloroplast Genome Of Scenedesmus Sp. And Dunaliella Sp.

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US Patent:
20120252054, Oct 4, 2012
Filed:
Sep 14, 2010
Appl. No.:
13/496149
Inventors:
Kyle M. Botsch - San Diego CA, US
Amy C. Curran - San Diego CA, US
Wendy Levine - Santee CA, US
Bryan O'Neill - Carlsbad CA, US
Shawn Joseph Szyjka - San Diego CA, US
Michael Mendez - San Diego CA, US
Assignee:
SAPPHIRE ENERGY INC - SAN DIEGO CA
International Classification:
C12N 1/13
C12N 15/79
C12Q 1/02
US Classification:
435 29, 4352572, 435471
Abstract:
The present disclosure relates to methods of transforming various species of algae, for example, algae from the genus and the genus , vectors and nucleic acid constructs useful in conducting such transformations, and recombinant algae, for example, and produced using the vectors and methods disclosed herein.

Compositions And Methods For Using Genetically Modified Orthologous Enzymes

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US Patent:
20220411766, Dec 29, 2022
Filed:
Oct 2, 2020
Appl. No.:
17/765767
Inventors:
- San Diego CA, US
Kyle BOTSCH - San Diego CA, US
Tasha ALTHEIDE - San Diego CA, US
Matthew SAUNDERS - San Diego CA, US
International Classification:
C12N 9/10
Abstract:
Described herein are prenyltransferases including non-natural variants thereof having at least one amino acid substitution as compared to its corresponding natural or unmodified prenyltransferases and that are capable of at least two-fold greater rate of formation of cannabinoids such as cannabigerolic acid, cannabigerovarinic acid, cannabigerorcinic acid, and cannabigerol, as compared to a wild type control. Prenyltransferase variants also accept different hydrophobic substrates (e.g., “donor” molecules), compared to wild type controls, to create different minor and novel cannabinoids. Prenyltransferase variants also demonstrated regioselectivity to desired cannabinoid isomers such as CBGA (3-GOLA), 3-GDVA, 3-GOSA, and CBG (2-GOL). The prenyltransferase variants can be used to form prenylated aromatic compounds, and can be expressed in an engineered microbe having a pathway to such compounds, which include 3-GOLA, 3-GDVA, 3-GOSA, and CBG. 3-GOLA can be used for the preparation of cannabigerol (CBG), which can be used in therapeutic compositions.

Compositions And Methods For Using Genetically Modified Enzymes

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US Patent:
20230029027, Jan 26, 2023
Filed:
Apr 13, 2020
Appl. No.:
17/602676
Inventors:
- San Diego CA, US
Joseph NOEL - San Diego CA, US
Michael BURKART - San Diego CA, US
Jeremy LANOISELEE - San Diego CA, US
Kyle BOTSCH - La Mesa CA, US
Matthew SAUNDERS - San Diego CA, US
International Classification:
C12N 9/10
C12P 17/06
C12P 7/42
C12P 7/22
Abstract:
The disclosure relates to the biosynthesis of cannabinoids and related prenylated phenolic compounds using recombinant enzymes. In particular, the disclosure provides recombinant prenyltransferase enzymes engineered to produce a greater amount of a desired product, or to have a greater ability to catalyze a reaction using a desired substrate, as compared to the wild type prenyltransferase. The disclosure also provides methods of preparing such recombinant enzymes; as well as methods of use thereof in improving the biosynthesis of cannabinoids and related prenylated phenolic compounds.

Compositions And Methods For Using Genetically Modified Enzymes

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US Patent:
20210301267, Sep 30, 2021
Filed:
Oct 27, 2020
Appl. No.:
17/081724
Inventors:
- San Diego CA, US
Joseph NOEL - San Diego CA, US
Michael BURKART - San Diego CA, US
Jeremy LANOISELEE - San Diego CA, US
Kyle BOTSCH - La Mesa CA, US
Matthew SAUNDERS - San Diego CA, US
International Classification:
C12N 9/10
C12P 7/42
Abstract:
The disclosure relates to the biosynthesis of cannabinoids and related prenylated phenolic compounds using recombinant enzymes. In particular, the disclosure provides recombinant mutant ORF2 enzymes engineered to produce a greater amount of a desired product, or to have a greater ability to catalyze a reaction using a desired substrate, as compared to WT ORF2. The disclosure also provides methods of preparing such ORF2 mutant enzymes; as well as methods of use thereof in improving the biosynthesis of cannabinoids and related prenylated phenolic compounds.

Compositions And Methods For Using Genetically Modified Enzymes

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US Patent:
20200123511, Apr 23, 2020
Filed:
Nov 13, 2019
Appl. No.:
16/682845
Inventors:
- San Diego CA, US
Joseph NOEL - San Diego CA, US
Michael BURKART - San Diego CA, US
Jeremy LANOISELEE - San Diego CA, US
Kyle BOTSCH - La Mesa CA, US
Matthew SAUNDERS - San Diego CA, US
International Classification:
C12N 9/10
C12P 7/42
Abstract:
The disclosure relates to the biosynthesis of cannabinoids and related prenylated phenolic compounds using recombinant enzymes. In particular, the disclosure provides recombinant mutant ORF2 enzymes engineered to produce a greater amount of a desired product, or to have a greater ability to catalyze a reaction using a desired substrate, as compared to WT ORF2. The disclosure also provides methods of preparing such ORF2 mutant enzymes; as well as methods of use thereof in improving the biosynthesis of cannabinoids and related prenylated phenolic compounds.

Use Of Fungicides In Liquid Systems

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US Patent:
20140378513, Dec 25, 2014
Filed:
Oct 12, 2012
Appl. No.:
14/351540
Inventors:
- SAN DIEGO CA, US
Craig A Behnke - San Diego CA, US
Kyle M Botsch - San Diego CA, US
Nicole A Heaps - San Diego CA, US
Christopher Del Meenach - Mesilla Park NM, US
International Classification:
C12N 1/12
A01N 43/56
C12Q 1/68
A01N 43/40
US Classification:
514352, 435 612, 506 2, 435 615
Abstract:
The present disclosure provides methods to detect pests in liquid culture systems for the growth of microalgae. The disclosure further provides methods to treat and control pests in a liquid system and for methods to increase yields of microalgae grown in a liquid culture systems. Methods are provided for the growth, monitoring, treatment and harvesting of microalgae from liquid culture systems.
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Kyle M Botsch from La Mesa, CA, age ~40 Get Report