US Patent:
20040208792, Oct 21, 2004
Inventors:
John Linton - Lincoln MA, US
Karl Yoder - Stoneham MA, US
Robert Hess - Arlington MA, US
Leila Hasan - Boston MA, US
Robert Ellis - Burlington MA, US
Tanya Kanigan - Cambridge MA, US
Kristine Friesen - Cambridge MA, US
Arrin Katz - Somerville MA, US
Colin Brenan - Marblehead MA, US
Tom Morrison - Winchester MA, US
Javier Garcia - Lexington MA, US
International Classification:
B01L003/00
C12M003/00
US Classification:
422/099000, 422/102000, 435/286100
Abstract:
A system for holding at least one of sample and reagent for analysis. The system includes a pair of parallel covers, at least one of which is light transmissive, of which pair a light transmissive cover forms a top, and of which pair the other forms a bottom. A frame is disposed between the covers to define, in relation to the covers, an interior volume. The frame and the covers are associated with one another to form a case, the case being substantially tight to liquids. A microfluidic array is disposed in the interior volume. The array includes a sheet of material having a pair of opposed surfaces, a thickness, and a plurality of through-holes running through the thickness between the surfaces, the through-holes containing at least one of sample and reagent.