US Patent:
20210155932, May 27, 2021
Inventors:
- Basel, CH
Antoine DEWECK - Basel, CH
Javad GOLJI - Cambridge MA, US
Gregory HOFFMAN - Cambridge, MA
Francesco HOFMANN - Basel, CH
Audrey KAUFFMANN - Basel, CH
Konstantinos John MAVRAKIS - Cambridge MA, US
William SELLERS - Cambridge MA, US
Tobias SCHMELZLE - Basel, CH
Frank Peter STEGMEIER - Cambridge MA, US
International Classification:
C12N 15/115
C12N 15/113
C12N 9/22
A61K 45/06
G01N 33/574
Abstract:
The disclosure provides novel personalized therapies, kits, transmittable forms of information and methods for use in treating patients having cancer, wherein the cancer is amenable to therapeutic treatment with an inhibitor, e.g., an inhibitor of any of the targets disclosed herein. Kits, methods of screening for candidate inhibitors, and associated methods of treatment are also provided.