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Kiyoshi Ariizumi

from Dallas, TX
Age ~70
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Also known as:
Kiyoshi Arizumi, Kana Ariizumi, Keishiro Ariizumi, Kiyoshi I
Phone and address:
17815 Cypress Falls Dr, Dallas, TX 75287
(972) 820-8226
Related to:
Kana Ariizumi, 47Keishiro Ariizumi, 40Junko Ariizumi, 73
Connected to:
Engin B Arik, 68Ilgaz T Arikan, 53Marwan I Arikat, 49Julie A Arildsen, 57Christina R Arillo, 41Patrick M Arillo, 63Maria Arima, 99Perry P Arima, 64Ronald H Arima, 88Toshihiro Arima, 63

Kiyoshi Ariizumi Phones & Addresses

  • 17815 Cypress Falls Dr, Dallas, TX 75287 (972) 820-8226
  • 9607 Walnut St, Dallas, TX 75243 (972) 680-1634
  • 6201 Windhaven Pkwy, Plano, TX 75093 (469) 443-1679
  • 6201 Windhaven Pkwy #2824, Plano, TX 75093 (972) 443-1679
  • 7804 Kinman Ln, Plano, TX 75024 (972) 208-8542
  • 6910 Parkridge Blvd, Irving, TX 75063 (972) 556-1696 (972) 556-9526
  • Denton, TX

Work

Company: Ut southwestern medical center Position: Associate professor

Industries

Hospital & Health Care

Resumes

Resumes

Kiyoshi Ariizumi Photo 1

Associate Professor

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Location:
Dallas, TX
Industry:
Hospital & Health Care
Work:
UT Southwestern Medical Center
Associate Professor

Publications

Us Patents

Unique Dendritic Cell-Associated C-Type Lectins, Dectin-1 And Dectin-2 Compositions And Uses Thereof

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US Patent:
7071171, Jul 4, 2006
Filed:
Sep 14, 1999
Appl. No.:
09/396492
Inventors:
Kiyoshi Ariizumi - Dallas TX, US
Akira Takashima - Irving TX, US
Assignee:
Board of Regents the University of Texas System - Austin TX
International Classification:
A61K 48/00
C07H 21/04
US Classification:
514 44, 536 241
Abstract:
Novel genes expressed selectively by long-term dendritic cell (DC) lines (XS series) from murine epidermis which retain important features of resident epidermal Langerhans cells (LC) are provided. These genes encode distinct type II membrane-integrated polypeptides, each consisting of a cytoplasmic domain, a transmembrane domain, an extracellular connecting domain, and a C-terminal extracellular domain that exhibits significant homology to the carbohydrate recognition domains (CRD)) of C-type lectins. Expression of both genes is highly restricted to cells of DC lineage (including epidermal LC). Thus, these genes encode new, DC-specific members of the C-type lectin family, now termed “DC-associated C-type lectin-1 and -2” (dectin-1 and dectin-2). Two isoforms of the dectin-1 molecule and five isoforms of the dectin-2 molecule have also been identified. The invention further provides His-tagged fusion proteins comprising 6x histidine and the extracellular domain of dectin-1 or dectin-2.

Unique Dendritic Cell-Associated C-Type Lectins, Dectin-1 And Dectin-2; Compositions And Uses Thereof

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US Patent:
7129039, Oct 31, 2006
Filed:
Jul 23, 2002
Appl. No.:
10/201060
Inventors:
Kiyoshi Ariizumi - Dallas TX, US
Akira Takashima - Irving TX, US
Assignee:
Board of Regents The University of Texas System - Austin TX
International Classification:
C12Q 1/00
G01N 33/53
US Classification:
435 4, 436501
Abstract:
Novel genes expressed selectively by long-term dendritic cell (DC) lines (XS series) from murine epidermis which retain important features of resident epidermal Langerhans cells (LC) are provided. These genes encode distinct type II membrane-integrated polypeptides, each consisting of a cytoplasmic domain, a transmembrane domain, an extracellular connecting domain, and a C-terminal extracellular domain that exhibits significant homology to the carbohydrate recognition domains (CRD) of C-type lectins. Expression of both genes is highly restricted to cells of DC lineage (including epidermal LC). Thus, these genes encode new, DC-specific members of the C-type lectin family, now termed “DC-associated C-type lectin-1 and -2” (dectin-1 and dectin-2). Two isoforms of the dectin-1 molecule and five isoforms of the dectin-2 molecule have also been identified. The invention further provides His-tagged fusion proteins comprising 6× histidine and the extracellular domain of dectin-1 or dectin-2.

Keptin-A Novel Keratinocyte-Specific Proteinase Inhibitor

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US Patent:
20030211587, Nov 13, 2003
Filed:
May 7, 2002
Appl. No.:
10/141530
Inventors:
Kiyoshi Ariizumi - Plano TX, US
Ponciano Cruz - Dallas TX, US
Assignee:
Board of Regents, The University of Texas System
International Classification:
C07H021/04
C12N009/99
A61K038/57
C12P021/02
C12N005/06
C07K016/40
US Classification:
435/184000, 435/069200, 435/320100, 435/325000, 514/012000, 536/023200, 530/388260, 435/338000
Abstract:
The present invention provides a novel keratinocyte-specific secreted protein identified as keptin that inhibits an inflammatory response and activity of proteinase, as well as methods for treating hyperproliferative inflammatory skin diseases using proteinase inhibitor keptin. The invention provides a therapeutic agent for treating psoriasis and squamous cell carcinomas and other inflammatory skin related diseases.

Dc-Hil Conjugates For Treatment Of T-Cell Disorders

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US Patent:
20090297479, Dec 3, 2009
Filed:
Mar 26, 2009
Appl. No.:
12/411898
Inventors:
Kiyoshi Ariizumi - Dallas TX, US
Ponciano D. Cruz - Dallas TX, US
International Classification:
A61K 38/21
A61K 39/395
C12N 9/00
C07K 19/00
US Classification:
424 857, 4241731, 4241781, 4241831, 435183, 5303917
Abstract:
The present invention relates to the use of DC-HIL and fragments and variants thereof to selectively target toxins to activated T-cells expressing a unique form of syndecan-4 that is not found on other cells. Thus, the toxin is delivered only to activated T-cells, and not to other syndecan-4 expressing cells. Such toxin-DC-HIL conjugates are useful in the treatment of T-cell inflammatory disorders such as dermatitis, autoimmune disease, and graft rejection, as well as T-cell lymphomas.

Unique Dendritic Cell-Associated C-Type Lectins, Dectin-1 And Dectin-2; Compositions And Uses Thereof

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US Patent:
60461586, Apr 4, 2000
Filed:
Dec 20, 1996
Appl. No.:
8/772440
Inventors:
Kiyoshi Ariizumi - Dallas TX
Akira Takashima - Irving TX
Assignee:
Board of Regents The University of Texas Systems - Austin TX
International Classification:
A61K 3804
C07K 708
C07K 14705
C07K 1900
US Classification:
514 2
Abstract:
Novel genes expressed selectively by long-term dendritic cell (DC) lines (XS series) from murine epidermis which retain important features of resident epidermal Langerhans cells (LC) are provided. These genes encode distinct type II membrane-integrated polypeptides, each consisting of a cytoplasmic domain, a transmembrane domain, an extracellular connecting domain, and a C-terminal extracellular domain that exhibits significant homology to the carbohydrate recognition domains (CRD) of C-type lectins. Expression of both genes is highly restricted to cells of DC lineage (including epidermal LC). Thus, these genes encode new, DC-specific members of the C-type lectin family, now termed "DC-associated C-type lectin-1 and -2" (dectin-1 and dectin-2). Two isoforms of the dectin-1 molecule and five isoforms of the dectin-2 molecule have also been identified. The invention further provides His-tagged fusion proteins comprising 6. times.

Anti-Dc-Hil Antibodies For Cancer Diagnosis, Prognosis And Therapy

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US Patent:
20200206343, Jul 2, 2020
Filed:
Dec 31, 2019
Appl. No.:
16/731285
Inventors:
Kiyoshi ARIIZUMI - Dallas TX, US
Ponciano CRUZ - Dallas TX, US
Assignee:
The Board of Regents of the University of Texas System - Austin TX
International Classification:
A61K 39/395
C07K 16/28
A61K 35/15
A61K 45/06
C12Q 1/6886
G01N 33/574
C12Q 1/68
C07K 16/30
Abstract:
The present disclosure is directed to antibodies that bind to DC-HIL on the surface of myeloid-derived suppressor cells, and thus antagonize the T cell suppressor function of these cells, as well as their use in diagnosing and treating cancers such as melanoma.
Control profile
Kiyoshi Ariizumi from Dallas, TX, age ~70 Get Report