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Kimberlyn Frazier Card

from Pembroke Pines, FL
Age ~56

Kimberlyn Card Phones & Addresses

  • 1120 87Th Ave, Hollywood, FL 33025 (954) 435-2826 (954) 435-7922
  • Pembroke Pines, FL
  • Lakeland, FL
  • Boxborough, MA
  • Hydeville, VT

Business Records

Name / Title
Company / Classification
Phones & Addresses
Kimberlyn F Card
Secretary
OASIS MISSION STORE INC
12201 SW 14 St, Hollywood, FL 33025
Kimberlyn F. Card
Secretary
OASIS CHURCH OF SOUTH FLORIDA, INC
Baptist Church
12201 SW 14 St, Hollywood, FL 33025
(954) 433-4838, (954) 433-2004

Publications

Us Patents

P53 Binding T Cell Receptor Molecules

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US Patent:
7456263, Nov 25, 2008
Filed:
Jun 5, 2002
Appl. No.:
10/163084
Inventors:
Linda A. Sherman - LaJolla CA, US
Kimberlyn F. Card - Pembroke Pines FL, US
Jon A. Weidanz - Amarillo TX, US
Hing C. Wong - Weston FL, US
Elizabeth L. Thomson - Miami FL, US
International Classification:
C07K 16/30
US Classification:
53038822, 5303873
Abstract:
The invention provides T-cell receptor (TCR) molecules comprising a Vα chain and a Vβ chain that bind peptides derived from the p53 protein, preferably, the human p53 protein. The TCR molecules include both heterodimeric molecules and single chain molecules which specifically bind a sequence preferably spanning about amino acid positions 264-272 of the p53 protein displayed in the context of an HLA molecule, preferably, HLA-A2. 1. Also disclosed are methods for making and using such TCR molecules. The invention has a wide spectrum of useful application including therapeutic uses and use in the detection of cells expressing p53 protein.

Polyspecific Binding Molecules And Uses Thereof

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US Patent:
8105830, Jan 31, 2012
Filed:
Nov 5, 2002
Appl. No.:
10/287941
Inventors:
Jon A. Weidanz - Miami FL, US
Kimberlyn F. Card - Pembroke Pines FL, US
Linda A. Sherman - La Jolla CA, US
Norman R. Klinman - La Jolla CA, US
Hing C. Wong - Weston FL, US
Assignee:
Altor BioScience Corporation - Miramar FL
International Classification:
C12N 5/00
C12N 1/06
US Classification:
435375, 514 2, 530300, 530350, 5303871, 5303877, 5303887, 53038875, 5303888, 5303917, 4241301, 4241331, 4241351, 4241531, 4241541, 4241731
Abstract:
The present invention relates to polyspecific binding molecules and particularly single-chain polyspecific binding molecules that include at least one single-chain T-cell receptor (sc-TCR) covalently linked through a peptide linker sequence to at least one single-chain antibody (sc-Ab). Further disclosed are methods and compositions for testing and using the molecules.

T Cell Receptor Fusions And Conjugates And Methods Of Use Thereof

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US Patent:
20030144474, Jul 31, 2003
Filed:
Jun 5, 2001
Appl. No.:
09/874907
Inventors:
Jon Weidanz - Amarillo TX, US
Kimberlyn Card - Pembroke Pines FL, US
Hing Wong - Weston FL, US
Assignee:
Sunol Molecular Corporation
International Classification:
C07K016/46
C07K014/705
US Classification:
530/350000, 530/391100
Abstract:
Featured is T cell receptor complexes designed to redirect the immune system against various diseases. The T cell receptor complexes of the invention have been engineered to recognize target antigen in a functionally bispecific nature. Fusion protein complexes and protein conjugate complexes are comprised of high affinity antigen-specific TCR and biologically active proteins and/or effector molecules. Also featured is methods of production of T cell receptor fusion and conjugate complexes as well as therapeutic compositions for use of the complexes.

Modulation Of T -Cell Receptor Interactions

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US Patent:
20040253632, Dec 16, 2004
Filed:
May 16, 2001
Appl. No.:
09/859012
Inventors:
Peter Rhode - Miami FL, US
Vaughan Wittman - Weston FL, US
Jon Weidanz - Amarillo TX, US
Martin Burkhardt - Miami FL, US
Kimberlyn Card - Pembroke Pines FL, US
Rony Tal - Coral Springs FL, US
Jorge Acevedo - Thousand Oaks CA, US
Hing Wong - Weston FL, US
Assignee:
Sunol Molecular Corporation
International Classification:
G01N033/53
G01N033/567
US Classification:
435/007100, 435/007200
Abstract:
Disclosed are methods for identifying compounds that modulate an immune complex that includes a T cell receptor (TCR) and a major histocompatibility complex (MHC) antigen. The invention has many useful applications including providing high throughput screening assays for detecting compositions that can modulate an immune response.

Soluble Tcr Molecules And Methods Of Use

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US Patent:
20050214284, Sep 29, 2005
Filed:
Nov 10, 2004
Appl. No.:
10/985271
Inventors:
Heather Belmont - North Miami Beach FL, US
Kimberlyn Card - Pembroke Pines FL, US
Xiaoyun Zhu - Miami FL, US
International Classification:
A61K039/395
G01N033/53
G01N033/567
US Classification:
424144100, 435007200
Abstract:
Disclosed are compositions and methods for detecting cells or tissue comprising a peptide antigen presented in the context of an MHC or HLA complex. The invention has a wide range of applications including providing a highly sensitive method for detecting cancer cells.

Fusion Proteins Comprising Bacteriophage Coat Protein And Asingle-Chain T Cell Receptor

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US Patent:
20070116718, May 24, 2007
Filed:
Jun 15, 2006
Appl. No.:
11/455225
Inventors:
Jon Weidanz - Amarillo TX, US
Kimberlyn Card - Pembroke Pines FL, US
Hing Wong - Weston FL, US
International Classification:
A61K 39/12
C07H 21/04
C12P 21/04
C07K 14/005
C07K 14/705
C12N 15/86
US Classification:
424204100, 536023720, 530350000, 435069700, 435456000, 435325000
Abstract:
The present invention relates to novel fusion proteins comprising a bacteriophage coat protein and a single-chain T cell receptor and uses of such complexes. In one aspect, the invention relates to soluble fusion protein comprising a bacteriophage coat protein covalently linked to a single-chain T cell receptor which comprises a V-alpha chain covalently linked to a V-beta chain by a peptide linker sequence. The soluble fusion proteins of the invention are useful for a variety of applications including: 1) making a bacteriophage library for displaying single-chain T cell receptors for use in screens for identification and isolation of ligands that bind single-chain T cell receptors, and 2) methods for isolating soluble and fully functional single-chain T cell receptors from the fusion proteins.

Polyspecific Binding Molecules And Uses Thereof

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US Patent:
20120230995, Sep 13, 2012
Filed:
Dec 22, 2011
Appl. No.:
13/335362
Inventors:
Jon A. Weidanz - Abilene TX, US
Kimberlyn F. Card - Pembroke Pines FL, US
Linda A. Sherman - La Jolla CA, US
Norman R. Klinman - La Jolla CA, US
Hing C. Wong - Weston FL, US
Assignee:
Altor BioScience Corporation - Miramar FL
International Classification:
A61K 39/395
A61P 35/00
US Classification:
4241351
Abstract:
The present invention relates to polyspecific binding molecules and particularly single-chain polyspecific binding molecules that include at least one single-chain T-cell receptor (sc-TCR) covalently linked through a peptide linker sequence to at least one single-chain antibody (sc-Ab). Further disclosed are methods and compositions for testing and using the molecules.

T Cell Receptor Fusions And Conjugates And Methods Of Use Thereof

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US Patent:
20130115191, May 9, 2013
Filed:
Sep 12, 2012
Appl. No.:
13/612178
Inventors:
Jon A. Weidanz - Abilene TX, US
Kimberlyn F. Card - Pembroke Pines FL, US
Hing C. Wong - Weston FL, US
Assignee:
ALTOR BIOSCIENCE CORPORATION - Miramar FL
International Classification:
A61K 39/42
C07K 16/08
A61K 39/395
A61K 39/385
C07K 14/705
US Classification:
424 852, 530350, 530351, 5303873, 4241941, 4241341, 424 851, 530399
Abstract:
Featured is T cell receptor complexes designed to redirect the immune system against various diseases. The T cell receptor complexes of the invention have been engineered to recognize target antigen in a functionally bispecific nature. Fusion protein complexes and protein conjugate complexes are comprised of high affinity antigen-specific TCR and biologically active proteins and/or effector molecules. Also featured is methods of production of T cell receptor fusion and conjugate complexes as well as therapeutic compositions for use of the complexes.
Kimberlyn Frazier Card from Pembroke Pines, FL, age ~56 Get Report