US Patent:
20090136570, May 28, 2009
Inventors:
Bhagwant Rege - Collegeville PA, US
Kimberly Kaighn - Glen Mills PA, US
Soumojeet Ghosh - Lansdale PA, US
Laman Alani - Foster City CA, US
International Classification:
A61K 9/20
A61K 31/513
A61K 31/519
A61P 31/18
A61K 31/506
US Classification:
424465, 514269, 5142594, 514215
Abstract:
Orally administered, taste-masked tablets and granules contain (a) a hydroxypyrimidinone carboxamide, a hydroxy-tetrahydropyridopyrimidinone carboxamide, or a related carboxamide compound, or a pharmaceutically acceptable salt thereof, (b) a taste-masking polymer, (c) a superdisintegrant, and optionally other excipients. The carboxamide compound is an HIV integrase inhibitor, and the tablets and granules are suitable for use in the inhibition of HIV integrase, the treatment or prophylaxis of HIV infection, and the treatment or prophylaxis or delay in the onset of AIDS.