Kenneth G Mayhan

52449130, Sep 14, 1993

Nov 19, 1991

7/794544

Stephen L. Coulter - Irvine CA
Kenneth G. Mayhan - Irvine CA
Christy L. H. Oviatt - Mission Viejo CA
Steven R. Morehead - Riverside CA

Baxter International Inc. - Deerfield IL

A61K 3144
A61K 3114

514358

Compositions and methods for dissolving calculi deposits in humans are disclosed. The compositions include solutions of quaternary ammonium salts and are particularly effective for the contact dissolution of pigment portions of biliary tract calculi such as gallstones. The solutions preferably further include mineral chelating agent and disulfide bond cleaving agent to aid in deaggregating mineral components and glycoprotein components of calculi.

48634450, Sep 5, 1989

Jul 30, 1984

6/635772

Kenneth G. Mayhan - Irvine CA
Bernice I. Romo - Alhambra CA
Robert L. Murtfeldt - Redondo Beach CA
William J. Bertrand - Sunnymeade CA

Baxter Travenol Laboratories, Inc. - DE

A61M 100

604317

An assembly for inhibiting microbial growth in collected body fluid includes a reservoir for collecting the fluid, and a tablet in the reservoir, which tablet dissolves in the collected fluid to produce hydrogen peroxide in an amount sufficient to inhibit microbial growth in the collected fluid. The tablet is partially coated with an insoluble coating which leaves a portion of the tablet uncoated to provide a constant surface area exposed to the collected body fluid, which surface area is of a size to provide sufficient hydrogen peroxide for inhibition of microbial growth.

49940252, Feb 19, 1991

Aug 29, 1989

7/400212

Paul DeAntonio - Westminster CA
Kenneth G. Mayhan - Irvine CA
John T. Sorensen - Costa Mesa CA

Baxter International Inc. - Deerfield IL

A61M 100

604 28

Disclosed is a method for dissolving cholesterol-rich calculi, most preferably gallstones in vivo, comprising contacting the calculus with a fluid compound of the formula R-X, R having 2 to 4 carbon atoms with substituents consisting of hydrogen of halogen, X being halogen, and wherein if X is fluorine, at least one substituent is selected from the group consisting of hydrogen, chlorine, bromine, or iodine. Usually R-X is 2-bromo-2-chloro-1,1,1-trifluoroethane (also referred to as Halothane. ) Other compounds of particular interest are 2-chloro-1,2,-dibromo-1,1,2-trifluoroethane, 1-bromo-2-chloro-1,1,2-trifluoroethane, 2,3-dibromo-1,1,1-trifluoropropane, 2-iodo-1,1,1-trifluoroethane, 1,2-dichloro-1,1-difluoroethane, 1,1,2-trichloro-2,3,3-trifluorocyclobutane, hexafluoro-1,1,3,4,-tetrachlorobutane, 1,1,1-trichlorotrifluoroethane, and 1,2-dibromo-tetrafluoroethane. Furthermore, Halothane and MtBE in combination effectively dissolve cholesterol-rich calculi. Finally, dissolution can be enhanced by adding to the dissolution solvent up to about 50 percent by volume of a lower alcohol.

55341772, Jul 9, 1996

Feb 14, 1992

7/835665

Kenneth G. Mayhan - Irvine CA

C02F 500

510245

The present invention is directed to compositions useful for removing products of metal corrosion from corroded metals which consists essentially of an aqueous liquid solution of malonic acid, a surfactant and an organic solvent selected from the group consisting of formamide, dimethylformamide, and dimethylsulfoxide.

45956324, Jun 17, 1986

Feb 6, 1984

6/577300

Kenneth G. Mayhan - Irvine CA
Robert A. Janssen - Eden Prairie MN
Roger F. Drake - Costa Mesa CA

American Hospital Supply Corporation - Evanston IL

B32B 2728
B32B 2516

428409

A process for modifying the surface of a preformed polymeric substrate to impart lubricity and other desired properties thereto, without at the same time significantly altering the bulk properties of the substrate, by epoxidizing the substrate's surface and reacting the epoxide groups so formed with a fluorocarbon capable of cleaving the epoxide rings and covalently bonding thereto. The article so formed is also disclosed.

45899649, May 20, 1986

Feb 14, 1984

6/580119

Kenneth G. Mayhan - Irvine CA
Robert A. Janssen - Eden Prairie MN
William J. Bertrand - Sunnymead CA

American Hospital Supply Corporation - Evanston IL

C08F29118

522 85

A process for modifying the surface characteristics of a pre-formed polymeric substrate to impart hydrophilicity, hydrophobicity, or other desired properties thereto, by peroxidizing the surface of the substrate and then allowing the active sites along the polymer chains to generate free radicals which induce graft polymerization of a suitable ethylenic monomer (or other ethylenically-unsaturated compound) onto the surface of the substrate is described. Such graft copolymerization is undertaken in the presence of variable valence metal ions in a reduced state under acidic conditions and at selected reaction times and relatively low temperatures, and ideally in the presence of squarate ions (diketocyclobutenediol) to control the physical characteristics of the surface graft and to restore the metal ions to their lower valence state without at the same time producing deleterious by-products.

43115730, Jan 19, 1982

Oct 8, 1980

6/195103

Kenneth G. Mayhan - Irvine CA
Robert A. Janssen - Irvine CA
William J. Bertrand - Sunnymeade CA

American Hospital Supply Corporation - Evanston IL

C08F 210
C08F29118
C08F29106
C08J 716

20415915

A process for modifying the surface characteristics of a pre-formed polymeric substrate to impart hydrophilicity, hydrophobicity, or other desired properties thereto, by peroxidizing the surface of the substrate and then allowing the active sites along the polymer chains to generate free radicals which induce graft polymerization of a suitable ethylenic monomer (or other ethylenically-unsaturated compound) onto the surface of the substrate is described. Such graft copolymerization is undertaken in the presence of variable valence metal ions in a reduced state under acidic conditions and at selected reaction times and relatively low temperatures, and in the presence of squarate ions (diketocyclobutenediol) to control the physical characteristics of the surface graft and to restore the metal ions to their lower valence state without at the same time producing deleterious by-products.