Kelvin Li Phones & Addresses
-
Sunnyvale, CA
-
Fremont, CA
-
San Francisco, CA
-
Los Altos Hills, CA
-
San Diego, CA
-
La Jolla, CA
-
813 Inverness Way, Sunnyvale, CA 94087
Publications
Us Patents
Methods To Engineer Stratified Cartilage Tissue
View pageUS Patent:
20030077821, Apr 24, 2003
Filed:
Sep 13, 2002
Appl. No.:
10/244035
Inventors:
Robert Sah - San Diego CA, US
Kelvin Li - San Diego CA, US
Travis Klein - San Diego CA, US
Barbara Schumacher - Cardiff by the Sea CA, US
Koichi Masuda - Wilmette IL, US
Eugene Thonar - Lockport IL, US
Kelvin Li - San Diego CA, US
Travis Klein - San Diego CA, US
Barbara Schumacher - Cardiff by the Sea CA, US
Koichi Masuda - Wilmette IL, US
Eugene Thonar - Lockport IL, US
International Classification:
A61K048/00
C12N005/08
C12N005/08
US Classification:
435/366000, 424/093210
Abstract:
The present invention is directed to a cultured, stratified cartilage tissue that comprises a tissue-engineered, cohesive cartilage construct comprised of two or more cartilage layers, wherein each cartilage layer comprises chondrogenic cells having a chondrocytic phenotype corresponding to chondrocytes present in: a superficial-tangential zone of natural cartilage; a middle-transitional zone of natural cartilage; a deep-radial zone of natural cartilage; or a calcified cartilage zone of natural cartilage.