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Keith R Fandrick

from Ridgefield, CT
Age ~46

Keith Fandrick Phones & Addresses

  • 317 Limestone Rd, Ridgefield, CT 06877 (203) 244-5600
  • 48 New Lebbon Rd, Sandy Hook, CT 06482 (203) 364-9087
  • Danbury, CT
  • Cambridge, MA
  • Somerville, MA
  • Forest Falls, CA
  • Brighton, MA
  • San Diego, CA
  • 48 New Lebbon Rd, Sandy Hook, CT 06482

Work

Company: Lam therapeutics Jan 2019 Position: Senior director, head of cmc and process chemistry

Education

Degree: Doctorates, Masters, Doctor of Philosophy School / High School: Harvard University 2001 to 2007 Specialities: Philosophy, Chemistry

Skills

Organic Chemistry • Chemistry • Organic Synthesis • Pharmaceutical Industry • Drug Discovery • Nuclear Magnetic Resonance • Liquid Chromatography Mass Spectrometry • Synthetic Organic Chemistry • Drug Development • Purification • Chromatography • Medicinal Chemistry • Drug Design • Lc Ms • Research and Development • High Performance Liquid Chromatography • Cmc Development • Chemical Engineering • Good Manufacturing Practice • Project Management • Analytical Development • Outsourcing Management • Pharmaceutical Process Development • Formulation Development • Nmr

Emails

Industries

Biotechnology

Resumes

Resumes

Keith Fandrick Photo 1

Senior Director, Head Of Cmc And Process Chemistry

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Location:
Sandy Hook, CT
Industry:
Biotechnology
Work:
Lam Therapeutics
Senior Director, Head of Cmc and Process Chemistry

Lam Therapeutics May 2017 - Dec 2018
Director Cmc and Process Chemistry

Boehringer Ingelheim Jun 1, 2016 - May 2017
Senior Principal Scientist, Chemical Development

Boehringer Ingelheim May 2011 - May 2016
Principal Scientist, Chemical Development

Boehringer Ingelheim Jun 2007 - Apr 2011
Senior Scientist: Chemical Development
Education:
Harvard University 2001 - 2007
Doctorates, Masters, Doctor of Philosophy, Philosophy, Chemistry
Uc San Diego 1997 - 2001
Bachelors, Bachelor of Science, Chemistry
Skills:
Organic Chemistry
Chemistry
Organic Synthesis
Pharmaceutical Industry
Drug Discovery
Nuclear Magnetic Resonance
Liquid Chromatography Mass Spectrometry
Synthetic Organic Chemistry
Drug Development
Purification
Chromatography
Medicinal Chemistry
Drug Design
Lc Ms
Research and Development
High Performance Liquid Chromatography
Cmc Development
Chemical Engineering
Good Manufacturing Practice
Project Management
Analytical Development
Outsourcing Management
Pharmaceutical Process Development
Formulation Development
Nmr

Publications

Us Patents

Synthesis Of Inhibitors Of 11Beta-Hydroxysteroid Dehydrogenase Type 1

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US Patent:
20110269957, Nov 3, 2011
Filed:
Jul 23, 2009
Appl. No.:
13/054959
Inventors:
Keith R. Fandrick - Sandy Hook CT, US
Joe Ju Gao - Southbury CT, US
Wenjie Li - Hopewell Junction NY, US
Zhi-Hui Lu - Newtown CT, US
Yongda Zhang - Richmond VA, US
Assignee:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH - Ingelheim am Rhein
International Classification:
C07D 413/10
C07D 265/10
US Classification:
544 96, 544 97
Abstract:
Disclosed are syntheses of 11β-HSD1 inhibitors and corresponding intermediates that are promising for the treatment of a variety of disease states including diabetes, metabolic syndrome, obesity, glucose intolerance, insulin resistance, hyperglycemia, hypertension, hypertension-related cardiovascular disorders, hyperlipidemia, deleterious gluco-corticoid effects on neuronal function (e.g. cognitive impairment, dementia, and/or depression), elevated intra-ocular pressure, various forms of bone disease (e.g., osteoporosis), tuberculosis, leprosy (Hansen's disease), psoriasis, and impaired wound healing (e.g., in patients that exhibit impaired glucose tolerance and/or type 2 diabetes).

Process For Preparing Carboxamidine Compounds

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US Patent:
20130211130, Aug 15, 2013
Filed:
Feb 7, 2013
Appl. No.:
13/761434
Inventors:
Keith R. FANDRICK - Sandy Hook CT, US
Joe Ju GAO - Southbury CT, US
Jason Alan MULDER - New Milford CT, US
Nitinchandra D. PATEL - Danbury CT, US
Xingzhong ZENG - New Milford CT, US
Assignee:
Boehringer Ingelheim International Gmbh - Ingelheim am Rhein
International Classification:
C07C 259/14
C07C 47/24
C07C 251/40
C07C 271/12
US Classification:
560163, 564229, 568425, 564265
Abstract:
The present invention relates to a process of making a compound of formula (I):Wherein, R, R, Rand X are as defined herein.

Process For The Preparation Of An Hiv Integrase Inhibitor

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US Patent:
20140094609, Apr 3, 2014
Filed:
Oct 2, 2013
Appl. No.:
14/044189
Inventors:
- Foster City CA, US
Xiang Wang - Foster City CA, US
Keith R. Fandrick - Sandy Hook CT, US
Joe Ju Gao - Southbury CT, US
Nizar Haddad - Danbury CT, US
Serge R. Landry - Saint-Jerome, CA
Wenjie Li - Hopewell Junction NY, US
Zhi-Hui Lu - Newtown CT, US
Bo Qu - Brookfield CT, US
Diana C. Reeves - New Milford CT, US
Carl Thibeault - Mascouche, CA
Yongda Zhang - Sandy Hook CT, US
International Classification:
C07D 491/06
C07D 401/04
C07D 409/04
C07D 215/14
C07D 405/04
US Classification:
546 89, 546173, 546 98
Abstract:
The present invention is directed to an improved process for the preparation of Compounds of Formula (I), which are useful in the treatment of HIV infection. In particular, the present invention is directed to an improved process for the preparation of (2S)-2-tert-butoxy-2-(4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl)acetic acid, which is useful in the treatment of HIV infection.

Process For The Preparation Of An Hiv Integrase Inhibitor

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US Patent:
20140094610, Apr 3, 2014
Filed:
Oct 3, 2013
Appl. No.:
14/045033
Inventors:
- Foster City CA, US
Philomen DECROOS - Middlebury CT, US
Keith R. FANDRICK - Sandy Hook CT, US
Joe Ju GAO - Southbury CT, US
Nizar HADDAD - Danbury CT, US
Zhi-Hui LU - Newtown CT, US
Bo QU - Brookfield CT, US
Sonia RODRIGUEZ - New Milford CT, US
Chris H. SENANAYAKE - Brookfield CT, US
Yongda ZHANG - Sandy Hook CT, US
Wenjun TANG - Southbury CT, US
International Classification:
C07D 491/06
C07D 417/02
C07D 409/02
C07D 401/02
C07D 215/14
C07D 405/02
US Classification:
546 89, 546173, 546 99
Abstract:
The present invention is directed to an improved process for the preparation of Compounds of Formula (I) or salts thereof which are useful in the treatment of HIV infection. In particular, the present invention is directed to an improved process for the preparation of (2S)-2-tert-butoxy-2-(4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl)acetic acid or salt thereof which is useful in the treatment of HIV infection.
Keith R Fandrick from Ridgefield, CT, age ~46 Get Report