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Kazumi Kobayashi

from Arlington, MA
Age ~73
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Also known as:
Kazumi Marchionni
Phone and address:
24 Twin Circle Dr, Arlington, MA 02474
(617) 378-5991
Related to:
Jancie L Mills, 49Joseph M Marchionni, 35Liza Mills, 44Ellen Mills, 63Barbara M Mills, 70Carl M Rizzuto, 88Tracey A Cook
Connected to:
Akitoshi Kobayashi, 58Alexander G Kobayashi, 45Brenda L Kobayashi, 70Brent K Kobayashi, 41Chigusa Kobayashi, 61Collin L Kobayashi, 45Crystal E Kobayashi, 45Dorine T Kobayashi, 70Garrett J Kobayashi, 36Grace T Kobayashi, 76

Kazumi Kobayashi Phones & Addresses

  • 24 Twin Circle Dr, Arlington, MA 02474 (617) 378-5991
  • Cambridge, MA
  • 24 Twin Circle Dr, Arlington, MA 02474 (781) 698-8422

Resumes

Resumes

Kazumi Kobayashi Photo 1

Senior Principal Scienitist

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Location:
Arlington, MA
Industry:
Biotechnology
Work:
Mit Chemistry Dept
Post Doctroral Fellow
Biogen
Senior Principal Scienitist
Education:
Kyoto University
Doctorates, Doctor of Philosophy, Biochemistry, Philosophy
Interests:
Science and Technology
Education
Environment
Languages:
English
Japanese
Kazumi Kobayashi Photo 2

Senior Principal Scientist

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Location:
Cambridge, MA
Industry:
Biotechnology
Work:
Biogen
Senior Principal Scientist

Publications

Us Patents

Methods For Detecting Half-Antibodies Using Chip Based Gel Electophoresis

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US Patent:
20070275481, Nov 29, 2007
Filed:
Nov 23, 2004
Appl. No.:
10/579639
Inventors:
Elena Vasilyeva - Swampscott MA, US
Francine Brown - Amherst NH, US
Matthias Kretschmer - Weston MA, US
Peter Bove - Burlington VT, US
Hans Fajardo - Wakefield MA, US
Frederick Taylor - Milton MA, US
Rohin Mhatre - Lexington MA, US
Kazumi Kobayashi - Arlington MA, US
Amy Dingley - Roslindale MA, US
Assignee:
BIOGEN IDEC MA INC. - CAMBRIDGE MA
International Classification:
G01N 33/561
C07K 1/00
C07K 14/00
C07K 16/18
G01N 33/00
US Classification:
436516000, 436086000, 530350000, 530387100, 530409000
Abstract:
The invention provides a method of using chip-based gel electrophoresis to determine the presence of polypeptides with selected disulfide linkage patterns, for example, completely formed tetrameric antibodies as compared to incompletely formed heterodimeric half-antibodies. The invention further features a kit, comprising a chip, and instructions for conducting the foregoing method. The methods and kits of the invention are amendable to high throughput applications for the monitoring of production and quality control of recombinant therapeutic antibodies.

Calcium Channel Antagonists And Methodology For Their Identification

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US Patent:
53129288, May 17, 1994
Filed:
Feb 11, 1991
Appl. No.:
7/654104
Inventors:
Stanley M. Goldin - Lexington MA
Kazumi Kobayashi - Arlington MA
Andrew G. Knapp - Salem MA
Lee Margolin - Belmont MA
Subbarao Katragadda - Belmont MA
Deborah Daly - Melrose MA
N. Laxma Reddy - Malden MA
Assignee:
Cambridge Neuroscience - Cambridge MA
International Classification:
C07D20920
A61K 31405
US Classification:
548495
Abstract:
A substantially pure compound of the formula: ##STR1## wherein each of R. sub. 1 and R. sub. 2, independently, is H, CH. sub. 3, CF. sub. 3, F, Cl, Br, I, OH, OCH. sub. 3, OCF. sub. 3, SH, SCH. sub. 3, NH. sub. 2, N. sub. 3, NO. sub. 2, CN, COOH, CONH. sub. 2, CH. sub. 2 CONH. sub. 2, or SO. sub. 2 NH. sub. 2 ; R. sub. 3 is H, CH. sub. 3, COOH, CONH. sub. 2, or COOR where R is C. sub. 1-4 alkyl; each R. sub. 4, independently, is H or C. sub. 1-6 alkyl; X is CH. sub. 2, CH. sub. 2 CH. sub. 2, CH. dbd. CH, or CH. sub. 2 CH. sub. 2 CH. sub. 2 ; ##STR2## each Z, independently, is H, CH. sub. 3, or Q where Q is a hydrophobic acyl, benzoyl, phenacetyl, benzyloxycarbonyl, alkoxycarbonyl, or N-methyl-dihydropyridine-3-carbonyl linked to N by an amide bond which is cleavable by an endogenous central nervous system enzyme; D is H or ##STR3## where R. sub. 5 is H or C. sub. 1-4 alkyl; m is an integer from 2 to 12, inclusive; and each n, independently, is an integer from 2 to 12, inclusive; a therapeutic composition including such compound; and a process for identifying calcium channel antagonists.

Fucosylated Guanosine Disulfates As Excitatory Amino Acid Antagonists

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US Patent:
54381304, Aug 1, 1995
Filed:
Jan 15, 1993
Appl. No.:
8/004928
Inventors:
Stanley Goldin - Lexington MA
James Fisher - Arlington MA
Kazumi Kobayashi - Arlington MA
Laxma Reddy - Malden MA
Andy Knapp - Salem MA
Lee Margolin - Belmont MA
Kevin D. McCormick - Ithaca NY
Assignee:
Cambridge NeuroScience, Inc. - Cambridge MA
Cornell Research Foundation, Inc. - Ithaca NY
International Classification:
C07H 19167
US Classification:
536 2781
Abstract:
A compound consisting of a base, a ribose and a fucose, in which the base is a purine or a pyrimidine, the ribose has R. sub. 1 and R. sub. 2 attached respectively to any two of 2'-O, 3'-O and 5'-O, and the fucose has R. sub. 3, R. sub. 4 and R. sub. 5 attached respectively to any three of 1"-O, 2"-O, 3"-O and 4"-O, wherein each R. sub. 1, R. sub. 2, R. sub. 3, R. sub. 4 and R. sub. 5 is H, acetate, sulfate, phosphate, or a metallic salt of acetate, sulfate or phosphate; and the base is linked to the ribose via a bond between 9-N of the base and 1'-O of the ribose when the base is a purine or via a bond between 1-N of the base and 1'-C of the ribose when the base is a pyrimidine and the ribose is linked to the fucose via a bond between any one of 2'-O, 3'-O and 5'-O of the ribose and 1"-C of the fucose.
Control profile
Kazumi Kobayashi from Arlington, MA, age ~73 Get Report