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Kathleen Mortell Phones & Addresses

  • 7777 Elmwood Ave, Middleton, WI 53562 (608) 836-8388
  • Madison, WI
  • 2018 Oakley Ave, Chicago, IL 60647
  • 1734 Sumner Pl, Hayward, CA 94541
  • Union City, CA
  • Oshkosh, WI
  • Berkeley, CA

Publications

Us Patents

Substituted Diazabicycloalkane Derivatives

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US Patent:
7399765, Jul 15, 2008
Filed:
Sep 16, 2004
Appl. No.:
10/942035
Inventors:
William H. Bunnelle - Mundelein IL, US
Jianguo Ji - Libertyville IL, US
Tao Li - Grayslake IL, US
Jennifer M. Pace - Grayslake IL, US
Karin R. Tietje - Mundelein IL, US
Kathleen H. Mortell - Chicago IL, US
Diana L. Nersesian - Gurnee IL, US
Michael R. Schrimpf - Grayslake IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31/501
A61K 31/5025
A61K 31/4427
A61K 31/42
A61K 31/4436
C07D 401/04
C07D 403/04
C07D 405/04
C07D 409/04
C07D 471/04
C07D 491/04
C07D 498/04
C07D 513/04
C07D 515/04
A61P 29/00
C07D 231/12
C07D 417/04
C07D 285/08
C07D 285/12
C07D 239/42
C07D 263/34
C07D 413/02
C07D 413/14
C07D 271/107
C07D 487/04
C07D 215/12
C07D 261/12
C07D 401/14
C07D 413/04
C07D 23/56
A61K 31/41
A61K 31/425
A61K 31/426
A61K 31/427
A61K 31/4245
A61K 31/441
A61K 31/422
A61K 31/4155
US Classification:
51425206, 544238, 544333, 546113, 546256, 5462764, 546176, 5462767, 5462774, 51425202, 51425205, 51425204, 514256, 514406, 514372, 514363, 514361, 514374, 514364, 514339, 514357, 514378, 514338, 5483751, 548181, 548128, 548136, 548235, 548143, 548247, 5483625
Abstract:
Compounds of formula (I)Z-Ar—Ar  (I)wherein Z is a diazabicyclic amine, Aris a 5- or 6-membered aromatic ring, and Aris selected from the group consisting of an unsubstituted or substituted 5- or 6-membered heteroaryl ring; unsubstituted or substituted bicyclic heteroaryl ring; 3,4-(methylenedioxy)phenyl; carbazolyl; tetrahydrocarbazolyl; naphthyl; and phenyl; wherein the phenyl is substituted with 0, 1, 2, or 3 substituents in the meta- or para-positions. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions comprising compounds of formula (I) and methods for using such compounds and compositions.

Amide Derivatives As Positive Allosteric Modulators And Methods Of Use Thereof

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US Patent:
7786171, Aug 31, 2010
Filed:
Mar 26, 2009
Appl. No.:
12/412110
Inventors:
Michael R. Schrimpf - Grayslake IL, US
Kathleen H. Mortell - Chicago IL, US
Diana L. Nersesian - Gurnee IL, US
Chih-Hung Lee - Vernon Hills IL, US
Bruce Clapham - Lindenhurst IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31/166
C07C 323/09
US Classification:
514618, 564162
Abstract:
The invention relates to novel amide derivatives that are positive allosteric modulators of neuronal nicotinic receptors, compositions comprising the same, processes for preparing such compounds, and methods for using such compounds and compositions.

Thiazolylidine Urea And Amide Derivatives And Methods Of Use Thereof

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US Patent:
8383657, Feb 26, 2013
Filed:
Dec 18, 2008
Appl. No.:
12/338849
Inventors:
Ramin Faghih - Lake Forest IL, US
Gregory A. Gfesser - Lindenhurst IL, US
Kathleen H. Mortell - Chicago IL, US
Murali Gopalakrishnan - Libertyville IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31/427
C07D 277/04
C07D 277/12
US Classification:
514370, 548195
Abstract:
The invention relates to novel thiazolylidine urea and amide derivatives that are PAMs of neuronal nicotinic receptors, compositions comprising the same, processes for preparing such compounds, and methods for using such compounds and compositions.

Amide Derivatives As Positive Allosteric Modulators And Methods Of Use Thereof

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US Patent:
8536221, Sep 17, 2013
Filed:
Feb 6, 2009
Appl. No.:
12/367096
Inventors:
Kathleen H. Mortell - Chicago IL, US
Diana L. Nersesian - Gurnee IL, US
Michael R. Schrimpf - Grayslake IL, US
Chih-Hung Lee - Vernon Hills IL, US
Murali Gopalakrishnan - Libertyville IL, US
Assignee:
AbbVie Inc. - North Chicago IL
International Classification:
A01N 43/30
A61K 31/36
C07D 209/44
US Classification:
514464, 548469, 548470
Abstract:
The invention relates to novel amide derivatives that are PAMs of neuronal nicotinic receptors, compositions comprising the same, processes for preparing such compounds, and methods for using such compounds and compositions.

Amide Derivatives As Positive Allosteric Modulators And Methods Of Use Thereof

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US Patent:
7994223, Aug 9, 2011
Filed:
Jul 22, 2010
Appl. No.:
12/841547
Inventors:
Michael R. Schrimpf - Grayslake IL, US
Kathleen H. Mortell - Chicago IL, US
Diana L. Nersesian - Gurnee IL, US
Chih-Hung Lee - Vernon Hills IL, US
Bruce Clapham - Lindenhurst IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31/166
US Classification:
514618
Abstract:
The invention relates to novel amide derivatives that are positive allosteric modulators of neuronal nicotinic receptors, compositions comprising the same, processes for preparing such compounds, and methods for using such compounds and compositions.

Beta-Amino Acid Derivatives Useful For The Treatment Of Bacterial Infections

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US Patent:
20030125389, Jul 3, 2003
Filed:
Jul 25, 2002
Appl. No.:
10/202630
Inventors:
Bore Raju - Fremont CA, US
Sampathkumar Anandan - Fremont CA, US
Joaquim Trias - Millbrae CA, US
Prudencio Herradura - Berkeley CA, US
Kathleen Mortell - Chicago IL, US
Dinesh Patel - Fremont CA, US
International Classification:
A61K031/198
A61K031/44
A61K031/40
C07D213/56
C07C243/10
C07C239/14
US Classification:
514/563000, 514/357000, 514/408000, 562/560000, 546/336000, 548/567000
Abstract:
The invention provides compounds that are useful for the treatment of bacterial infections in mammals. More specifically, it is directed to beta-amino acid derivatives or pharmaceutically acceptable salts, prodrugs, or isomers of those compounds that are useful for the treatment of such infections.

Fused Bicycloheterocycle Substituted Quinuclidine Derivatives

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US Patent:
20050137204, Jun 23, 2005
Filed:
Dec 17, 2004
Appl. No.:
11/015236
Inventors:
Jianguo Ji - Libertyville IL, US
Tao Li - Grayslake IL, US
Kathleen Mortell - Chicago IL, US
Michael Schimpf - Grayslake IL, US
Diana Nersesian - Gurnee IL, US
Liping Pan - Gurnee IL, US
International Classification:
A61K031/506
A61K031/501
A61K031/497
A61K031/4745
C07D453/02
US Classification:
514252040, 544238000, 544333000, 544405000, 546135000, 514255050, 514256000, 514305000
Abstract:
Compounds of formula (I) wherein n is 0, 1, or 2; A is N or N—O; X is O, S, —NH—, and —N-alkyl-; Aris a 6-membered aromatic ring; and Aris a fused bicycloheterocycle. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.

Fused Bicycloheterocycle Substituted Quinuclidine Derivatives

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US Patent:
20050245531, Nov 3, 2005
Filed:
Jun 15, 2005
Appl. No.:
11/153762
Inventors:
Jianguo Ji - Libertyville IL, US
Tao Li - Grayslake IL, US
Kathleen Mortell - Chicago IL, US
Michael Schrimpf - Grayslake IL, US
Diana Nersesian - Gurnee IL, US
Liping Pan - Gurnee IL, US
William Bunnelle - Mundelein IL, US
International Classification:
C07D453/04
A61K031/506
A61K031/501
US Classification:
514252040, 514305000, 546135000, 514256000, 544238000, 544333000
Abstract:
Compounds of formula (I) wherein n is 0, 1, or 2; A is N or N—O—; X is O, S, —NH—, and —N-alkyl-; Aris a 6-membered aromatic ring; and Aris a fused bicycloheterocycle. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.
Kathleen R Mortell from Madison, WI, age ~58 Get Report