Inventors:
Kang Yao - Delray Beach FL, US
Nan An - Boynton Beach FL, US
Khanh Duc Huynh - Medford MA, US
Assignee:
AMERICAN MAGNETIC ENGINEERING, INC. - DELRAY BEACH FL
International Classification:
B03C 1/033
B03C 1/28
B01L 9/00
Abstract:
A magnetic separation device for immunoassay using a two-sided plate for multi-well microplate separation via a flat side containing a magnetic block and a back side of magnetic microplate structure containing a matrix of permanent magnets. The present invention relates to a multi-purpose magnetic separation device that has two sides of magnetic separation function. The flat side of magnetic separation device includes magnet block, metal or plastic sheet on top surface and a pin to secure the assay plate. The back side of magnetic separation device is a multi-well structure that includes a plurality of permanent magnets placed in the spaces between the adjacent wells. There are different magnetic configurations for the multi-well structure, which ensures that each well is pulled by at least one strong permanent magnet. These strong permanent magnets are polarized laterally, i.e., its magnetic flux line points toward the side of the well. This way, the micro magnetic sample in the fluid is drawn toward the sides of the wells instead of the bottom, which makes it easy to observe and operate.