Inventors:
Timothy J. Guzi - Chatham NJ, US
Kamil Paruch - Garwood NJ, US
Michael P. Dwyer - Scotch Plains NJ, US
Ronald J. Doll - Convent Station NJ, US
Viyyoor M. Girijavallabhan - Parsippany NJ, US
Carmen S. Alvarez - Livingston NJ, US
Tin-Yau Chan - Edison NJ, US
Chad Knutson - Garwood NJ, US
Vincent Madison - Mountain Lakes NJ, US
Thierry O. Fischmann - Scotch Plains NJ, US
Lawrence W. Dillard - Skillman NJ, US
Vinh D. Tran - Fountain Valley CA, US
Zhen Min He - Princeton NJ, US
Ray Anthony James - Bristol PA, US
Haengsoon Park - Plainsboro NJ, US
Assignee:
Schering Corporation - Kenilworth NJ
Pharmacopeia Drug Discovery, Inc. - Crambury NJ
International Classification:
C07D 487/04
Abstract:
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.