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Judit Jakus Phones & Addresses

  • Silver Spring, MD
  • 10316 Rockville Pike, Rockville, MD 20852
  • 11305 Shore Rd, Reston, VA 20190

Publications

Us Patents

Compositions And Methods For Inhibiting Deoxyhypusine Synthase And The Growth Of Cells

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US Patent:
53448464, Sep 6, 1994
Filed:
Dec 30, 1992
Appl. No.:
7/998231
Inventors:
Judit Jakus - Silver Spring MD
Myung H. Park - Potomac MD
Edith C. Wolff - Bethesda MD
John E. Folk - Derwood MD
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
International Classification:
C07C27904
A61K 31155
US Classification:
514634
Abstract:
Compositions and methods for the treatment of mammalian cells to inhibit cell growth, especially for inhibiting the proliferative cell growth associated with malignant and non-malignant disease, are provided. More particularly, a deoxyhypusine synthase inhibitor, typically, a mono- or bisguanyl diamine or polyamine, is administered to the cells. Also provided by this invention are diagnostic methods and kits for screening the cells of a patient to determine the effect of the deoxyhypusine synthase inhibitor on proliferation of the cells.
Judit Jakus from Silver Spring, MD, age ~64 Get Report