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Joseph P Kutzko

from Southborough, MA
Age ~68

Joseph Kutzko Phones & Addresses

  • 15 Newton St, Southborough, MA 01772 (508) 481-9955
  • 2 Blendon Woods Dr, Southborough, MA 01772
  • 4 Pleasant St, Fayville, MA 01745
  • Marlborough, MA
  • Framingham, MA
  • 15 Newton St, Southborough, MA 01772

Publications

Us Patents

Oligosaccharide-Protein Conjugates

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US Patent:
20110300120, Dec 8, 2011
Filed:
Dec 11, 2009
Appl. No.:
13/140272
Inventors:
Luis Z. Avila - Arlington MA, US
Clark Q. Pan - Sudbury MA, US
Patrick Finn - Weymouth MA, US
John Harrahy - Medway MA, US
Qun Zhou - Ashland MA, US
Yunxiang Zhu - Wayland MA, US
Paul A. Konowicz - Maynard MA, US
Duncan E. Paterson - Zurich, CH
Andreas Peer - Basel, CH
Joseph P. Kutzko - Southborough MA, US
Michael R. Reardon - North Attleboro MA, US
James E. Stefano - Hopkinton MA, US
Xiaoyang Zheng - Newton MA, US
Robert J. Miller - E. Bridgewater MA, US
Lauren Young - Hampton NH, US
International Classification:
A61K 38/43
C12N 9/96
A61P 3/00
C07H 1/00
C08B 37/00
C07K 2/00
A61K 38/02
US Classification:
424 943, 530395, 435188, 514 209, 536 171, 536 182
Abstract:
Provided herein are conjugates comprising a protein and an oligosaccharide of one of Formulae I-VI. Also provided herein are pharmaceutical compositions comprising such conjugates. Further provided herein are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-glycoprotein conjugate.

Purification Of Biologically Active Peptides From Milk

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US Patent:
62684876, Jul 31, 2001
Filed:
May 13, 1996
Appl. No.:
8/648235
Inventors:
Joseph P. Kutzko - Southboro MA
Michael L. Hayes - Acton MA
Lee T. Sherman - Northboro MA
Assignee:
Genzyme Transgenics Corporation - Framingham MA
International Classification:
C07K 114
C07K 116
US Classification:
530414
Abstract:
A method of separating a soluble milk component from milk is disclosed. The method involves the use of tangential flow filtration across a membrane to form a retentate and a permeate, combining the permeate with the original milk sample, and repeating this procedure until the milk has been sufficiently purified. Preferably, the milk is combined with a chelating agent, such as EDTA, to improve the purification efficiency. This procedure is advantageously employed with milk from transgenic animals which have been genetically altered to express exogenous proteins, such as therapeutic proteins, in their milk.

Oligosaccharide-Protein Conjugates

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US Patent:
20220242899, Aug 4, 2022
Filed:
Feb 14, 2022
Appl. No.:
17/671249
Inventors:
- Cambridge MA, US
Clark Q. PAN - Sudbury MA, US
Patrick FINN - Weymouth MA, US
John HARRAHY - Medway MA, US
Qun ZHOU - Ashland MA, US
Yunxiang ZHU - Wayland MA, US
Paul A. KONOWICZ - Maynard MA, US
Duncan E. PATERSON - Zurich, CH
Andreas PEER - Basel, CH
Joseph P. KUTZKO - Southborough MA, US
Michael R. REARDON - North Attleboro MA, US
James E. STEFANO - Hopkinton MA, US
Xiaoyang ZHENG - Newton MA, US
Robert J. MILLER - E. Bridgewater MA, US
Lauren YOUNG - Hampton NH, US
International Classification:
C07H 15/04
A61K 47/61
Abstract:
Provided herein are conjugates comprising a protein and an oligosaccharide of one of Formulae I-VI. Also provided herein are pharmaceutical compositions comprising such conjugates. Further provided herein are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-glycoprotein conjugate.

Oligosaccharide-Protein Conjugates

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US Patent:
20200216485, Jul 9, 2020
Filed:
Sep 24, 2019
Appl. No.:
16/581148
Inventors:
- Cambridge MA, US
Clark Q. PAN - Sudbury MA, US
Patrick FINN - Weymouth MA, US
John HARRAHY - Medway MA, US
Qun ZHOU - Ashland MA, US
Yunxiang ZHU - Wayland MA, US
Paul A. KONOWICZ - Maynard MA, US
Duncan E. PATERSON - Zurich, CH
Andreas PEER - Basel, CH
Joseph P. KUTZKO - Southborough MA, US
Michael R. REARDON - North Attleboro MA, US
James E. STEFANO - Hopkinton MA, US
Xiaoyang ZHENG - Newton MA, US
Robert J. MILLER - E. Bridgewater MA, US
Lauren YOUNG - Hampton NH, US
International Classification:
C07H 15/04
A61K 47/61
Abstract:
Provided herein are conjugates comprising a protein and an oligosaccharide of one of Formulae I-VI. Also provided herein are pharmaceutical compositions comprising such conjugates. Further provided herein are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-glycoprotein conjugate.

Oligosaccharide-Protein Conjugates

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US Patent:
20180002365, Jan 4, 2018
Filed:
Oct 7, 2016
Appl. No.:
15/288486
Inventors:
- Cambridge MA, US
Clark Q. PAN - Sudbury MA, US
Patrick FINN - Weymouth MA, US
John HARRAHY - Medway MA, US
Qun ZHOU - Ashland MA, US
Yunxiang ZHU - Wayland MA, US
Paul A. KONOWICZ - Maynard MA, US
Duncan E. PATERSON - Zurich, CH
Andreas PEER - Basel, CH
Joseph P. KUTZKO - Southborough MA, US
Michael R. REARDON - North Attleboro MA, US
James E. STEFANO - Hopkinton MA, US
Xiaoyang ZHENG - Newton MA, US
Robert J. MILLER - E. Bridgewater MA, US
Lauren YOUNG - Hampton NH, US
International Classification:
C07H 15/04
A61K 47/61
Abstract:
Provided herein are conjugates comprising a protein and an oligosaccharide of one of Formulae I-VI. Also provided herein are pharmaceutical compositions comprising such conjugates. Further provided herein are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-glycoprotein conjugate.

Oligosaccharide-Protein Conjugates

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US Patent:
20150175643, Jun 25, 2015
Filed:
Jul 29, 2014
Appl. No.:
14/445941
Inventors:
- Cambridge MA, US
Clark Q. Pan - Sudbury MA, US
Patrick Finn - Weymouth MA, US
John Harrahy - Medway MA, US
Qun Zhou - Ashland MA, US
Yunxiang Zhu - Wayland MA, US
Paul A. Konowicz - Maynard MA, US
Duncan E. Paterson - Zurich, CH
Andreas Peer - Basel, CH
Joseph P. Kutzko - Southborough MA, US
Michael R. Reardon - North Attleboro MA, US
James E. Stefano - Hopkinton MA, US
Xiaoyang Zheng - Newton MA, US
Robert J. Miller - E. Bridgewater MA, US
Lauren Young - Hampton NH, US
International Classification:
C07H 15/04
Abstract:
Provided herein are conjugates comprising a protein and an oligosaccharide of one of Formulae I-VI. Also provided herein are pharmaceutical compositions comprising such conjugates. Further provided herein are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-glycoprotein conjugate.
Joseph P Kutzko from Southborough, MA, age ~68 Get Report