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Joseph S Holoshitz

from Ann Arbor, MI
Age ~74
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Also known as:
Joseph M Holoshitz, Jose Holoshitz, Joesph Holoshitz, Joseph Z
Phone and address:
3580 Windemere Dr, Ann Arbor, MI 48105
(734) 996-4743
Related to:
Tamar Holoshitz, 36Yael Holoshitz, 41Malka Holoshitz
Connected to:
Alisha D Holota, 56Daniel J Holota, 33Michael C Holota, 74Bruce R Holoubek, 65Frank Holoubek, 60Sue E Holoubek, 70Jayson T Holovacs, 50Jimmy Holovacko, 51Cynthia J Holoviak, 64Gina Y Holowatuk, 60

Joseph Holoshitz Phones & Addresses

  • 3580 Windemere Dr, Ann Arbor, MI 48105 (734) 996-4743
  • Palo Alto, CA
  • 3580 Windemere Dr, Ann Arbor, MI 48105 (734) 417-6003

Work

Company: University Of MI Medcl Ctr-RHU Address: 1500 E Medical Center Dr, Ann Arbor, MI 48109 Phones: (734) 647-5900

Education

School / High School: Hadassah Medical School, The Hebrew University Of Jerusalem 1981

Languages

English

Awards

Healthgrades Honor Roll

Ranks

Certificate: Internal Medicine, 2000

Emails

m***[email protected]

Specialities

Rheumatology

Professional Records

Medicine Doctors

Joseph Holoshitz Photo 1

Dr. Joseph Holoshitz, Ann Arbor MI - MD (Doctor of Medicine)

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Specialties:
Rheumatology
Address:
University Of MI Medcl Ctr-RHU
1500 E Medical Center Dr, Ann Arbor, MI 48109
(734) 647-5900 (Phone)
Procedures:
Joint Drainage
Steroid Injections
Trigger Point Injections
Conditions:
Amyloidosis
Antiphospholipid Syndrome (APS)
Arthritis
Bursitis
Carpal Tunnel Syndrome
Chronic Neck Pain
Classic Polyarteritis Nodosa
Degenerative Disc Disease
Enthesopathy of Hip (incl. Trochanteric Bursitis)
Enthesopathy of Knee (incl. Bursitis of Knee)
Fibromyalgia
Giant Cell Arteritis
Gout
Hepatitis B - Immune Response
Immune Thrombocytopenic Purpura (ITP)
Lateral & Medial Epicondylitis (Tennis & Golf Elbow)
Low Back Pain
Lupus Erythematosus
Marfan Syndrome
Osteoarthritis
Osteoarthritis of Hand or Wrist
Osteoarthritis of Hip
Osteoarthritis of Knee
Osteoarthritis of Spine
Osteopenia
Osteoporosis
Patellofemoral Pain Syndrome or Knee Pain
Polymyalgia Rheumatica (PMR)
Polymyositis
Raynaud's Disease
Rheumatoid Arthritis
Sjögren's Syndrome
Spondylitis
Still's Disease
Systemic Lupus Erythematosus (SLE)
Systemic Sclerosis
Takayasu's Arteritis
Vasculitis
Certifications:
Internal Medicine, 2000
Rheumatology, 2002
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
University Of MI Medcl Ctr-RHU
1500 E Medical Center Dr, Ann Arbor, MI 48109

University of Michigan Health System
1500 East Medical Center Drive Spc 5474, Ann Arbor, MI 48109
Education:
Medical School
Hadassah Medical School, The Hebrew University Of Jerusalem
Graduated: 1981
Joseph Holoshitz Photo 2

Joseph Holoshitz

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Specialties:
Rheumatology
Work:
University Of Michigan Medical Center Taubman Center Rheumatology
1500 E Medical Ctr Dr FL 3, Ann Arbor, MI 48109
(734) 647-5900 (phone), (734) 936-3695 (fax)
Education:
Medical School
The Hebrew Univ, Hadassah Med Sch, Jerusalem, Israel
Graduated: 1981
Procedures:
Vaccine Administration
Conditions:
Acute Renal Failure
Cardiomyopathy
Cirrhosis
Gout
Heart Failure
Languages:
English
Description:
Dr. Holoshitz graduated from the The Hebrew Univ, Hadassah Med Sch, Jerusalem, Israel in 1981. He works in Ann Arbor, MI and specializes in Rheumatology. Dr. Holoshitz is affiliated with University Of Michigan Hospitals & Health Center.
Joseph Holoshitz Photo 3

Joseph Holoshitz, Ann Arbor MI

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Specialties:
Internal Medicine
Rheumatology
Work:
Ann Arbor Veterans Affairs Medical Center
2215 Fuller Rd, Ann Arbor, MI 48105
University of Michigan Medical School
1500 E Medical Center Dr, Ann Arbor, MI 48109
Education:
Hebrew University, Hadassah Medical School (1981)
Joseph Holoshitz Photo 4

Joseph Holoshitz, Ann Arbor MI

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Specialties:
Rheumatologist
Address:
1500 E Medical Center Dr, Ann Arbor, MI 48109

Business Records

Name / Title
Company / Classification
Phones & Addresses
Joseph Holoshitz
Joseph Holoshitz MD
Internist
1500 E Medical Ctr Dr, Ann Arbor, MI 48109
(734) 647-5900
Joseph Holoshitz
Rheumatology Specialist
Rheumatology University of Michigan
Health Practitioner's Office
1500 E Med Ctr Dr, Ann Arbor, MI 48109

Publications

Us Patents

Compositions For Treating Autoimmune Disease

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US Patent:
6518259, Feb 11, 2003
Filed:
May 22, 2000
Appl. No.:
09/575612
Inventors:
Joseph Holoshitz - Ann Arbor MI
James A. Shayman - Ann Arbor MI
Shi-Yu Tan - Ann Arbor MI
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
A61K 3166
US Classification:
514114, 514 24, 514 44, 514642
Abstract:
Methods and compositions are described for treating and diagnosing autoimmune diseases, and in particular for treating and detecting rheumatoid arthritis. Treatment is described with a new class of anti-RA drug, namely compounds that inhibit proliferation and induce apoptosis.

Methods And Compositions For The Treatment Of Diseases Associated With Signal Transduction Aberrations

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US Patent:
7074893, Jul 11, 2006
Filed:
Feb 25, 2004
Appl. No.:
10/786774
Inventors:
Joseph Holoshitz - Ann Arbor MI, US
Song Ling - Ypsilanti MI, US
Assignee:
Regents of the University of Michigan - Ann Arbor MI
International Classification:
A61K 38/04
US Classification:
530330, 530300
Abstract:
The present invention relates generally to therapeutic methods and compositions. More particularly, methods and compositions to counteract and reverse disease-causing signaling defects in diseases with underlying signal transduction aberrations, including but not limited to Alzheimer's Disease.

Methods And Compositions For The Treatment Of Mhc-Associated Conditions

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US Patent:
7208154, Apr 24, 2007
Filed:
May 13, 2004
Appl. No.:
10/845407
Inventors:
Joseph Holoshitz - Ann Arbor MI, US
Song Ling - Ypsilanti MI, US
Assignee:
Regents of the University of Michigan - Ann Arbor MI
International Classification:
A61K 38/04
US Classification:
4241781, 514 2, 530330
Abstract:
The present invention relates to methods and compositions for counteracting and reversing disease-causing signaling defects in disorders with underlying signal transduction aberrations, including but not limited to rheumatoid arthritis.

Methods And Compositions For The Treatment Of Diseases Associated With Signal Transduction Aberrations

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US Patent:
20030096748, May 22, 2003
Filed:
Jun 3, 2002
Appl. No.:
10/161959
Inventors:
Joseph Holoshitz - Ann Arbor MI, US
Song Ling - Ann Arbor MI, US
Assignee:
The Regents Of The University Of Michigan
International Classification:
A61K038/17
US Classification:
514/012000, 530/359000
Abstract:
The present invention relates generally to therapeutic methods and compositions. More particularly, methods and compositions to counteract and reverse disease-causing signaling defects in diseases with underlying signal transduction aberrations, including but not limited to Alzheimer's Disease.

Compositions And Methods For Treating Autoimmune Disease

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US Patent:
20030119789, Jun 26, 2003
Filed:
Oct 31, 2002
Appl. No.:
10/285011
Inventors:
Joseph Holoshitz - Ann Arbor MI, US
James Shayman - Ann Arbor MI, US
Shi-Yu Tan - Ann Arbor MI, US
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
A61K031/66
A61K031/445
A61K031/225
A61K031/495
US Classification:
514/114000, 514/255010, 514/328000, 514/561000, 514/547000
Abstract:
Methods and compositions are described for treating and diagnosing autoimmune diseases, and in particular for treating and detecting rheumatoid arthritis. Treatment is described with a new class of anti-RA drug, namely compounds that inhibit proliferation and induce apoptosis.

Method Of Treating Oxidative Stress-Associated Conditions With Isopentenyl Diphosphate

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US Patent:
20050215529, Sep 29, 2005
Filed:
Mar 21, 2005
Appl. No.:
11/085298
Inventors:
Joseph Holoshitz - Ann Arbor MI, US
Jie Zheng - Nanjing, CN
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
International Classification:
A61K031/66
US Classification:
514102000
Abstract:
It has been found that isopentenyl diphosphate possesses antioxidant effects 1000 to 10,000 times more potent than classical antioxidants, such as ascorbic acid, β-carotene, and α-tocopherol, and 100 times more potent than 2-chloroadenosine. With such high potency, as disclosed herein, isopentenyl diphosphate can be used to treat or prevent one or more oxidative stress-associated conditions by administering to a host, and preferably a human being, in need thereof a therapeutically effective amount of a pharmaceutical composition containing isopentenyl diphosphate or a pharmaceutically acceptable salt thereof. Additionally, isopentenyl diphosphate can be used to treat or prevent oxidative stress-associated damage to a biomolecule by administering isopentenyl diphosphate or a pharmaceutically acceptable salt thereof to the biomolecule.

Compositions And Methods For Inducing An Immune Response

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US Patent:
20120034252, Feb 9, 2012
Filed:
Jun 16, 2011
Appl. No.:
13/162382
Inventors:
Joseph Holoshitz - Ann Arbor MI, US
Song Ling - Ypsilanti MI, US
Xiujun Pi - Ann Arbor MI, US
Denise de Almeida - Dearborn MI, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
International Classification:
A61K 39/00
A61P 37/04
C07K 7/06
US Classification:
4241851, 530330
Abstract:
The present invention provides compositions and methods for inducing an immune response in a subject. In particular, the present invention provides compositions comprising immunostimulatory ligands (ISL) and methods of inducing an immune response in a subject therewith. Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.

Compositions And Methods For Inducing An Immune Response

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US Patent:
20120141516, Jun 7, 2012
Filed:
Dec 20, 2011
Appl. No.:
13/331354
Inventors:
Joseph Holoshitz - Ann Arbor MI, US
Song Ling - Ypsilanti MI, US
Xiujun Pi - Ann Arbor MI, US
Denise de Almeida - Dearborn MI, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
International Classification:
A61K 39/00
C07K 19/00
A61P 31/04
A61P 37/04
A61P 35/00
C07K 7/06
A61K 39/02
US Classification:
4241851, 530330, 530350
Abstract:
The present invention provides compositions and methods for inducing an immune response in a subject. In particular, the present invention provides compositions comprising immunostimulatory ligands (ISL) and methods of inducing an immune response in a subject therewith. Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.
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Joseph S Holoshitz from Ann Arbor, MI, age ~74 Get Report