Josep Domenech Phones & Addresses
-
New York, NY
Publications
Isbn (Books And Publications)
Construccio I Embelliment De La Basilica Del Sant Esperit De Terrassa, 1593-1993
View page
Author
Josep M. Domenech
ISBN #
8487023134
Wikipedia References
Josep Caballé Domenech
Us Patents
Assay For Screening Compounds That Selectively Decrease The Number Of Cancer Stem Cells
View pageUS Patent:
20140364402, Dec 11, 2014
Filed:
Mar 22, 2012
Appl. No.:
14/005058
Inventors:
Barry Smith - New York NY, US
Carlos Cordon-Cardo - New York NY, US
Daniel Petrylak - New York NY, US
Josep Domenech - New York NY, US
Mireia Castilla Martin - New York NY, US
Carlos Cordon-Cardo - New York NY, US
Daniel Petrylak - New York NY, US
Josep Domenech - New York NY, US
Mireia Castilla Martin - New York NY, US
Assignee:
THE ROGOSIN INSTITUTE - New York NY
International Classification:
G01N 33/50
A61K 31/573
A61K 31/4355
A61K 31/55
C12Q 1/68
G01N 33/574
A61K 31/573
A61K 31/4355
A61K 31/55
C12Q 1/68
G01N 33/574
US Classification:
514179, 435 29, 435 39, 506 10, 506 9, 435 723, 435 32, 514278, 51421204, 435 613
Abstract:
The present invention provides, inter alia, a method for identifying an agent that selectively decreases the number of cancer stem cells (CSCs). This method includes (a) contacting a CSC from a population of cells with a candidate agent; and (b) determining whether the candidate agent reduces the survival or growth of the CSC or increases differentiation of the CSC relative to a CSC that has not been contacted with the candidate agent. The method may be used as a high throughput screen.