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Josef Heuer Phones & Addresses

  • Traverse City, MI
  • 13866 Coldwater Dr, Carmel, IN 46032 (317) 313-0450
  • 5280 Avian Way, Carmel, IN 46033
  • Northport, MI
  • 8715 Orchard Grove Ln, Camby, IN 46113 (317) 821-4894
  • Indianapolis, IN
  • Greenwood, IN

Publications

Us Patents

Antibodies That Bind Tgf-Alpha And Epiregulin

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US Patent:
8613921, Dec 24, 2013
Filed:
Mar 28, 2012
Appl. No.:
13/432204
Inventors:
Catherine Brautigam Beidler - Poway CA, US
Josef George Heuer - Carmel IN, US
Ramona Judita Petrovan - San Diego CA, US
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
A61K 39/395
C07K 14/495
C07K 14/475
C07K 14/71
US Classification:
4241361, 4241391, 514 154
Abstract:
The present invention provides antibodies that bind human TGF-alpha and human Epiregulin and are characterized as having high affinity, selective, and strong neutralizing properties. The antibodies are useful in the treatment of diabetic nephropathy.

Treating T-Cell Mediated Diseases By Modulating Dr6 Activity

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US Patent:
20040043022, Mar 4, 2004
Filed:
Oct 16, 2002
Appl. No.:
10/257907
Inventors:
Josef Heuer - Indianapolis IN, US
Jinqi Liu - Plainsboro NJ, US
Songqing Na - Carmel IN, US
Ho Song - Carmel IN, US
Derek Yang - Carmel IN, US
International Classification:
A61K039/395
A61K031/00
US Classification:
424/143100, 514/001000
Abstract:
Novel methods are provided for the treatment or prevention of T cell mediated conditions in a mammal that comprise administering to said mammal a therapeutically effective amount of a pharmaceutical composition comprising at least one DR6 agonist or DR6 antagonist.

Therapeutic Methods Of Use For Lp229

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US Patent:
20040072745, Apr 15, 2004
Filed:
Jul 8, 2003
Appl. No.:
10/250959
Inventors:
Josef Heuer - Indianapolis IN, US
Kristine Kikly - Fortville IN, US
Eric Su - Carmel IN, US
International Classification:
A61K038/17
US Classification:
514/012000
Abstract:
Methods of use are provided for the treatment or prevention of poor healing or chronic wounds, skin diseases, sepsis, inflammation, immunodeficiencies, autoimmune diseases, infectious diseases, allergic diseases, and malignancies, particularly those disorders associated with the skin, by administering an LP229 polypeptide, protein, or epitope-recognizing antibody thereof to a patient in need of such therapy.

Use Of Lp82 To Treat Hematopoietic Disorders

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US Patent:
20040092445, May 13, 2004
Filed:
Aug 6, 2003
Appl. No.:
10/467431
Inventors:
Josef Heuer - Indianapolis IN, US
Ling Liu - Carmel IN, US
Timothy Noblitt - Fishers IN, US
International Classification:
A61K038/17
US Classification:
514/012000
Abstract:
The present invention relates to a method of using a mammalian gene sequence and polypeptides encoded thereby to treat mammalian hematopoietic disorders. More specifically the present invention relates to methods of using compositions comprising at least one LP82 agonist, LP82 antagonist, LP82 polynucleotide, LP82 polypeptide, and/or LP82 antibody for the prevention and/or treatment of mammalian hematopoietic disorders, including, but not limited to, anemia, leukemia, and hematopoietic conditions caused by bone marrow transplantation or chemo-/radiation therapy.

Lp Mammalian Proteins; Related Reagents

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US Patent:
20040126777, Jul 1, 2004
Filed:
Jul 25, 2003
Appl. No.:
10/470390
Inventors:
Ramesh Bhatt - Carmel IN, US
John Calley - lndianapolis IN, US
Josef Heuer - Indianapolis IN, US
Gerald Keleher - Indianapolis IN, US
Joanne Lancaster - Indianapolis IN, US
Qingqin Li - Flemington NJ, US
Deshun Lu - Carmel IN, US
Bradley Mills - Fountaintown IN, US
Santosh Mishra - Singapore, SG
Douglas Perkins - New Palestine IN, US
Scott Rowlinson - Indianapolis IN, US
Rosamund Smith - Greenfield IN, US
Eric Su - Carmel IN, US
He Wang - Carmel IN, US
Yu Zhi - Indianapolis IN, US
International Classification:
C12Q001/68
C07H021/04
C07K014/47
C07K016/18
US Classification:
435/006000, 435/069100, 435/320100, 435/325000, 530/350000, 530/388100, 536/023500
Abstract:
Isolated nucleic acid molecules encoding polypeptides from a human, reagents related thereto (including purified polypeptidesspecific antibodies) are provided. Methods of using said reagentsand diagnostic kits are also provided.

Novel Polypeptide Analogs And Fusions And Their Methods Of Use

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US Patent:
20040236088, Nov 25, 2004
Filed:
Jan 15, 2004
Appl. No.:
10/484122
Inventors:
Josef Heuer - Indianapolis IN, US
Songqing Na - Carmel IN, US
Angela Okragly - Indianapolis IN, US
Weijia Ou - Fishers IN, US
International Classification:
C07H021/04
US Classification:
536/023200, 435/069100, 435/320100, 435/325000, 530/388100, 530/350000, 424/094600
Abstract:
Novel polypeptide analogs and fusion proteins of a transmembrane protein, LP276, are provided. Vectors and host cells directed to these polypeptides are provided. Additionally, methods of use are provided for the treatment or prevention of allergic autoimmune diseases, type 1 diabetes, inflammation, immunodeficiencies, cancers, and infectious diseases by administering an LP276 polypeptide, analogs and fusion proteins thereof to a patient in need of such therapy.

Extracellular Junctional Adhesion Molecules

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US Patent:
20050159587, Jul 21, 2005
Filed:
Jul 5, 2002
Appl. No.:
10/481090
Inventors:
Josef Heuer - Indianapolis IN, US
Rosamund Smith - Greenfield IN, US
Eric Su - Carmel IN, US
International Classification:
C07K014/705
C07K016/28
C12P021/02
A61K039/395
US Classification:
530350000, 424143100, 435069100, 435320100, 435325000, 530388220, 536023500
Abstract:
This invention provides human extracellular junctional adhesion molecules (huJAM) and polynucleotides which identify and encode huJAM. The invention further provides methods using the molecules of the invention for treating, cancer and inflammatory, immune system, and cardiovascular disorders.

Method For Reducing Morbidity And Mortality In Critically Ill Patients

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US Patent:
20050176631, Aug 11, 2005
Filed:
Jan 8, 2003
Appl. No.:
10/499608
Inventors:
Josef Heuer - Indianapolis IN, US
Alexei Kharitonenkov - Carmel IN, US
International Classification:
A61K038/18
US Classification:
514012000
Abstract:
This invention relates to a novel method of reducing the mortality and morbidity in critically ill patients which comprises administering to the patients an effective amount of FGF-21.

Wikipedia

Grne (Iserlohn)

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Eine weltbekannte Erfindung aus der Grne ist die Heuerampel, die im Unternehmen Heuer-Hammer von Josef Heuer in den 1930er Jahren erfunden wurde. ...

Josef G Heuer from Traverse City, MI, age ~63 Get Report