US Patent:
20110086837, Apr 14, 2011
Inventors:
Marcia Belvin - Albany CA, US
Iris T. Chan - San Francisco CA, US
Lori Friedman - San Carlos CA, US
Klaus P. Hoeflich - Millbrae CA, US
John Prescott - San Francisco CA, US
Jeffrey Wallin - Berkeley CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
A61K 31/5377
A61P 35/02
Abstract:
The invention relates methods of treating a patient with locally advanced or metastatic solid tumors with a combination of an inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase or PI3K) and an inhibitor of mitogen activated protein kinase (MEK) described herein.