Giovanni C Pastrone

6589264, Jul 8, 2003

Jan 7, 2000

09/478818

Denise Barbut - New York NY
Giovanni Pastrone - Los Gatos CA
Tracy D. Maahs - Redwood City CA
Ross S. Tsugita - Mountain View CA

Edwards Lifesciences Corp. - Irvine CA

A61M 2900

606200, 604 9601, 60410104

A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.

6592546, Jul 15, 2003

Jan 30, 1998

09/016714

Denise Barbut - New York NY
Jonathan D. Root - San Francisco CA
Giovanni Pastrone - Los Gatos CA
Tracy D. Maahs - Redwood City CA
Ross S. Tsugita - Mountain View CA

Edwards Lifesciences Corp. - Irvine CA

A61M 2900

604 9601, 604104, 606200

A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.

6682543, Jan 27, 2004

Oct 24, 2001

10/055216

Denise R. Barbut - New York NY
Jonathan D. Root - San Francisco CA
Giovanni Pastrone - Los Gatos CA

C Edwards Lifesciences Corporation - Irvine CA

A61B 1722

606159

A method for removing plaque from the aorta is disclosed. A filter is introduced into a region of interest within the patients aorta. The filter is deployed downstream of a mobile aortic plaque within the aorta. An atherectomy assembly is operated to excise the plaque from the aorta. Emboli are captured by the filter. The filter and plaque are removed from the region of interest.

7306575, Dec 11, 2007

Jul 14, 2003

10/619760

Denise Barbut - New York NY, US
Jonathan D. Root - San Francisco CA, US
Giovanni Pastrone - Los Gatos CA, US
Tracy D. Maahs - Redwood City CA, US
Ross S. Tsugita - Mountain View CA, US

Edwards Lifesciences Corporation - Irvine CA

A61M 29/00

604 9601, 604104, 606200

A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.

20080065008, Mar 13, 2008

Nov 16, 2007

11/941872

Denise Barbut - New York NY, US
Jonathan Root - San Francisco CA, US
Giovanni Pastrone - Los Gatos CA, US
Tracy Maahs - Redwood City CA, US
Ross Tsugita - Mountain View CA, US

A61M 25/10

604096010

A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.

45523363, Nov 12, 1985

Jun 29, 1984

6/626266

Giovanni Pastrone - Los Gatos CA

OXIMETRIX, Inc. - Mountain View CA

F16K 702
F16K 4704

251331

A liquid flow regulator has a housing formed by two parts that snap together. The housing defines an axial bore, an inlet, an outlet and a plurality of axial grooves opening endwise of the inlet and laterally of the housing into the bore. The grooves taper axially so that the cross-sectional area of each groove gradually decreases from the inlet to nothing at a pont where the groove merges with the bore. The grooves have different axial lengths. An elastomeric sock fits within the bore. Means for expanding the sock radially outward into sealing engagement with the housing adjacent the bore is axially movable within the bore. Flow through the grooves and the bore is regulated by the axial position of the sock expanding means and the minimum cross-sectional area of the tapered, axial grooves at the axial location where the sock seals the bore. Axial adjustment of the sock expanding means sequentially opens and closes passage from the grooves through the bore to the bore outlet. Means are provided for disabling the sock expanding means to limit withdrawal of the sock expanding means from the bore.

56626711, Sep 2, 1997

Jul 17, 1996

8/683503

Denise Barbut - New York NY
Jonathan D. Root - San Francisco CA
Robert Rizzari - Haverhill MA
James M. Sellers - Hampstead NH
Giovanni Pastrone - Los Gatos CA
John McKenzie - San Carlos CA

Embol-X, Inc. - Portola Valley CA

A61M 2500

606170

An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping means, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.

63093995, Oct 30, 2001

Sep 7, 2000

9/656775

Denise R. Barbut - New York NY
Jonathan D. Root - San Francisco CA
Giovanni Pastrone - Los Gatos CA

SciMed Life Systems, Inc. - Maple Grove MN

A61M 2900

606159

An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping means, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.