Inventors:
Hong Liang - Gaithersburg MD, US
Kim Lee Sim - Gaithersburg MD, US
Xinhua Zhou - North Potomac MD, US
John Madsen - Jefferson MD, US
Renee J. Boerner - Apex NC, US
Firoz Rustom Mistry - Chapel Hill NC, US
Scot R. Shepard - Clayton NC, US
Jeffrey L. Schrimsher - Hillsborough NC, US
Lourdes L. Bermejo - Raleigh NC, US
Assignee:
The Children's Medical Center Corp. - Boston MA
Covance Biotechnology Services, Inc. - Cary NC
International Classification:
A23J 1/00
C07K 1/00
C12N 15/00
C12N 1/20
C12N 1/00
US Classification:
530416, 530412, 530413, 530414, 530417, 530350, 4353201, 4352523, 43525423
Abstract:
The present invention provides a method for recombinant production, recovery and purification of endostatin protein. This method may be employed for large scale recovery and purification of recombinantly-produced endostatin protein.