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John Iacomini Phones & Addresses

  • Harvard, MA
  • 22 Sycamore St, Somerville, MA 02143 (617) 623-8034
  • 20 Sycamore St, Somerville, MA 02143
  • 22 Sycamore St, Somerville, MA 02143 (617) 947-5910

Work

Company: Harvard Position: Associate prof.

Education

Degree: Graduate or professional degree

Emails

Industries

Research

Resumes

Resumes

John Iacomini Photo 1

Associate Prof. At Harvard

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Position:
associate prof. at harvard
Location:
Greater Boston Area
Industry:
Research
Work:
harvard
associate prof.

Publications

Us Patents

Induction Of Immunosuppression By Inhibition Of Atm

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US Patent:
20080279866, Nov 13, 2008
Filed:
Aug 17, 2007
Appl. No.:
11/889940
Inventors:
John Iacomini - Somerville MA, US
Jessamyn Bagley - Boston MA, US
Assignee:
The Brigham and Women's Hospital, Inc. - Boston MA
International Classification:
A61K 39/395
C12N 5/06
A61P 37/00
A61P 3/10
A61K 35/28
A61K 31/5377
US Classification:
4241731, 4353723, 424577, 5142315
Abstract:
The present invention is directed to methods of inducing immunosuppression in a patient by administering an inhibitor of the enzyme Ataxia telangiectasia mutated (Atm). The method may be used as a treatment for allergies, autoimmune diseases or lymphomas. It may also be used to prevent organ rejection in transplant patients and to treat or prevent graft versus host disease.

Antigen Presenting Cells

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US Patent:
20100203640, Aug 12, 2010
Filed:
Jun 5, 2008
Appl. No.:
12/663239
Inventors:
Thomas Wekerle - Vienna, AT
Rudolf Valenta - Theresienfeld, AT
Ulrike Baranyi - Vienna, AT
Birgit Linhart - Weissenkirchen, AT
Nina Pilat - Vienna, AT
Jessamyn Bagley - Boston MA, US
John Iacomini - Somerville MA, US
Martina Gattringer - Liebenau, AT
Assignee:
BIOMAY AG - Vienna
International Classification:
C12N 15/63
C12N 5/10
US Classification:
435455, 4353201, 435325
Abstract:
The present invention relates to a method for inducing specific long-lasting robust immunological tolerance towards at least one polypeptide derived from at least one allergen by transplanting a hematopoietic (stem) cell which is produced to display the said at least one polypeptide derived from at least one allergen.

Tolerance To Natural Antibody Antigens

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US Patent:
20020114787, Aug 22, 2002
Filed:
Jul 16, 2001
Appl. No.:
09/906387
Inventors:
John Iacomini - Somerville MA, US
Harout Dersimonian - Wellesley MA, US
David Sachs - Newton MA, US
International Classification:
A61K048/00
C12N005/06
US Classification:
424/093210, 435/325000
Abstract:
Methods of inducing tolerance in a recipient mammal to an antigen or to a graft which expresses the antigen. The methods typically include providing a cell from the recipient mammal which presents the antigen, and allowing the cell to produce or display the moiety in the recipient mammal, thereby inducing tolerance to the antigen.
John J Iacomini from Harvard, MA, age ~60 Get Report