Inventors:
Loic Barbedette - Dudley MA, US
John Hansson - Brooklyn CT, US
Richard Strack - Sturbridge MA, US
Kevin Tabor - Webster MA, US
Michael Weisser - Sturbridge MA, US
Assignee:
Schott Corporation - Elmsford NY
International Classification:
G02B 6/04
C12M 1/34
C12M 3/00
Abstract:
Well plates adaptable for specimen sampling in the biological, chemical and pharmaceutical sciences are fabricated by dissolving fusedly-retained cores from the cladding material of a fused fiber plate to define a capillary plate including first and second faces and a plurality of through-voids into which fluidic samples may be deposited for analysis. Closed-bottom wells are defined by bonding one of the first and second faces to a base plate or by securing into well-sealing positions over the open ends of selected through-voids optical elements, each of which optical elements exhibits a predetermined optical property. Cladding material including reducible ions is exposed to a reduction atmosphere in order to blacken selected regions of a well plate, thereby enhancing sample analysis by reducing such disadvantageous phenomena as autofluorescence.