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John D Denuzzio

from La Jolla, CA
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Also known as:
John Denuzzio, John David Denuzzio, Julia Denuzzio
Phone and address:
9237 Regents Rd UNIT 317, La Jolla, CA 92037
(919) 302-1145
Related to:
Susan B Denuzzio, 63Albert J Denuzzio, 71Marianna A DenuzzioAlexander Denuzzio, 34Catherine J Denuzzio, 70Julia K Denuzzio, 31
Connected to:
Jean A Denuzzio, 83Crystal K Denver, 53Kent E Denver, 79Larry E Denver, 89Nicole R Denver, 46Patrick Denver, 62Rachel M Denver, 32Russell F Denver, 68Stacey D Denver, 56Stanley D Denver, 78

John Denuzzio Phones & Addresses

  • 9237 Regents Rd UNIT 317, La Jolla, CA 92037 (919) 302-1145
  • 1500 Magers Landing Rd, Monkton, MD 21111 (410) 357-8038
  • 1909 Hawick Ct, Chapel Hill, NC 27516 (919) 932-5519
  • Baltimore, MD
  • Lovettsville, VA
  • Seabrook, NH

Work

Company: Bd Jan 2017 Position: Senior director, systems engineering, bd mms

Education

School / High School: Phillips Academy

Industries

Medical Devices

Resumes

Resumes

John Denuzzio Photo 1

Senior Director, Systems Engineering, Bd Mms

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Location:
1500 Magers Lndg Rd, Baltimore, MD
Industry:
Medical Devices
Work:
Bd
Senior Director, Systems Engineering, Bd Mms
Bd 2014 - 2014
Product Development Director
Bd 2000 - 2005
R and D Director
Education:
Phillips Academy
University of Pennsylvania
Doctorates, Doctor of Philosophy, Materials Science, Engineering

Publications

Us Patents

Chip-Based Isothermal Amplification Devices And Methods

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US Patent:
6379929, Apr 30, 2002
Filed:
Nov 19, 1997
Appl. No.:
08/974738
Inventors:
Mark A. Burns - Ann Arbor MI
David T. Burke - Ann Arbor MI
Brian N. Johnson - Ann Arbor MI
John D. DeNuzzio - Chapel Hill NC
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
C12P 1934
US Classification:
435 912, 435 911, 436501
Abstract:
Disclosed are methods and compositions for isothermal amplification of nucleic acids in a microfabricated substrate. Methods and compositions for the analysis of isothermally amplified nucleic acids in a microfabricated substrate are disclosed as well. The microfabricated substrates and isothermal amplification and detection methods provided are envisioned for use in various diagnostic methods, particularly those connected with diseases characterized by altered gene sequences or gene expression.

Low Cost Electrodes For An Iontophoretic Device

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US Patent:
6584349, Jun 24, 2003
Filed:
Nov 17, 1997
Appl. No.:
08/971458
Inventors:
John R. DeNuzzio - Chapel Hill NC
C. Randolph Bock - Durham NC
John L. Haynes - Chapel Hill NC
Vilambi Reddy - Bloomingdale NJ
Assignee:
Vyteris, Inc. - Fair Lawn NJ
International Classification:
A61N 130
US Classification:
604 20
Abstract:
The present invention claims an apparatus for transdermal delivery of medicaments, with novel electrode systems, which avoids burns caused by changes in pH or excessive current applied at the sight of delivery, which is low in cost and easy to manufacture. In the present invention, preferably, the anode of the electrode system is predominantly formed from a low-cost bulk base metal which includes a coating of a precious metal thereon. The cathode of the electrode system is preferably formed from an chemically inert material which is a poor electron condutor and is coated on a good electron conductive material which has poor chemical stability. The electrode system of the present invention is highly efficient, easy to manufacture and cost-effective.

Minimally-Invasive System And Method For Monitoring Analyte Levels

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US Patent:
6952604, Oct 4, 2005
Filed:
Dec 21, 2001
Appl. No.:
10/024506
Inventors:
John D. DeNuzzio - Chapel Hill NC, US
Assignee:
Becton, Dickinson and Company - Franklin Lakes NJ
International Classification:
A61B005/00
US Classification:
600345, 600347, 600365
Abstract:
A minimally-invasive analyte detecting device and method for using the same. The system and method employ a device having an active electrode optionally coated with a substance, and a counter-electrode that is configured at least partially surround the active electrode. The configuration of the auxiliary electrode and active electrode improves the current flow through the device and increases the sensitivity of the device. When the device is placed against the patient's skin, the active electrode is adapted to enter through the stratum corneum of a patient to a depth less than a depth in the dermis at which nerve endings reside. An electric potential is applied to the active electrode and the analyte level is determined based on the amount of current or charge flowing through the device.

System And Method For Initiating And Maintaining Continuous, Long-Term Control Of A Concentration Of A Substance In A Patient Using A Feedback Or Model-Based Controller Coupled To A Single-Needle Or Multi-Needle Intradermal (Id) Delivery Device

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US Patent:
7060059, Jun 13, 2006
Filed:
Oct 14, 2003
Appl. No.:
10/683466
Inventors:
Steven Keith - Chapel Hill NC, US
Robert S. Parker - Pittsburgh PA, US
Noel G. Harvey - Efland NC, US
Ronald J. Pettis - Cary NC, US
John D. DeNuzzio - Chapel Hill NC, US
Glenn Vonk - Fuquay-Varina NC, US
Assignee:
Becton, Dickinson and Company - Franklin Lakes NJ
International Classification:
A61M 31/00
US Classification:
604504, 604 67
Abstract:
A closed loop therapy system for controlling a concentration of a substance, such as blood glucose concentration, in the body of a user. The system and method employ a sensor system that measures a glucose level in the body, a controller that uses the measured glucose levels to generate an output that can be used to automatically or manually control an intradermal insulin infusion system to set a constant or time-varying profile of target blood glucose concentrations in a user, and then infuse an appropriate amount of insulin into the body of the user so as to reach and maintain the target values of the blood glucose concentration.

Integrated Lancet And Bodily Fluid Sensor

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US Patent:
7192405, Mar 20, 2007
Filed:
Sep 30, 2002
Appl. No.:
10/259798
Inventors:
John D. DeNuzzio - Chapel Hill NC, US
Steven Keith - Chapel Hill NC, US
Lawrence A. Monahan - Willow Spring NC, US
Phyllis Palmer - Durham NC, US
Bill Stewart - Cary NC, US
Todd M. Chelak - Waldwick NJ, US
Robert E. West - Basking Ridge NJ, US
William Allen - Houston TX, US
Frederick Karl - Beaverton OR, US
Lee Griswold - Norwalk CT, US
Assignee:
Becton, Dickinson and Company - Franklin Lakes NJ
International Classification:
A61B 5/00
US Classification:
600583
Abstract:
A lancing device integrated with a sensing strip and method of making and using the same are provided. A lance and analyte sensing strip are combined in a single, preferably disposable, device. In a preferred embodiment, a slot is provided in a support member so the lance can be engaged by a lance driver and driven into the skin producing a bodily fluid sample from a wound. The sensing area of the sensing strip is adjacent to the wound location reducing dexterity requirements for patients.

Minimally-Invasive System And Method For Monitoring Analyte Levels

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US Patent:
7426408, Sep 16, 2008
Filed:
Aug 2, 2004
Appl. No.:
10/903640
Inventors:
John D. DeNuzzio - Chapel Hill NC, US
Assignee:
Becton, Dickinson and Company - Franklin Lakes NJ
International Classification:
A61B 5/00
US Classification:
600345, 600347, 600365
Abstract:
A minimally-invasive analyte detecting device and method for using the same. The system and method employ a device having an active electrode optionally coated with a substance, and a counter-electrode that is configured at least partially surround the active electrode. The configuration of the auxiliary electrode and active electrode improves the current flow through the device and increases the sensitivity of the device. When the device is placed against the patient's skin, the active electrode is adapted to enter through the stratum corneum of a patient to a depth less than a depth in the dermis at which nerve endings reside. An electric potential is applied to the active electrode and the analyte level is determined based on the amount of current or charge flowing through the device.

Fiber Optic Device For Sensing Analytes

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US Patent:
7496392, Feb 24, 2009
Filed:
Nov 26, 2003
Appl. No.:
10/721797
Inventors:
Javier Alarcón - Durham NC, US
Kristin Weidemaier - Raleigh NC, US
Terry J. Amiss - Cary NC, US
John D. DeNuzzio - Chapel Hill NC, US
Christopher C. Herdman - Durham NC, US
Ross Wayne Jacobson - Hillsborough NC, US
J. Bruce Pitner - Durham NC, US
Douglas B. Sherman - Durham NC, US
Assignee:
Becton, Dickinson and Company - Franklin Lakes NJ
International Classification:
A61B 5/145
US Classification:
600317, 600310
Abstract:
A device for sensing analyte concentration, and in particular glucose concentration, in vivo or in vitro is described. An optical conduit, preferably an optical fiber, has an optical system at the proximal end of the optical conduit. A sensing element is attached to the distal end of the optical conduit, and may include at least one binding protein adapted to bind with at least one target analyte. The sensing element further may also include at least one reporter group that undergoes a luminescence change with changing analyte concentrations. Optionally, the sensing element includes reference groups with luminescence properties that are substantially unchanged by variations in the analyte concentrations.

Fiber Optic Device For Sensing Analytes And Method Of Making Same

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US Patent:
7787923, Aug 31, 2010
Filed:
Oct 19, 2004
Appl. No.:
10/967220
Inventors:
Javier Alarcon - Durham NC, US
Kristin Weidemaier - Raleigh NC, US
Terry J. Amis - Cary NC, US
John D. DeNuzzio - Monkton MD, US
Christopher C. Herdman - Chappaqua NY, US
Ross W. Jacobson - Hillsborough NC, US
J. Bruce Pitner - Durham NC, US
Douglas B. Sherman - Durham NC, US
Steven Keith - Chapel Hill NC, US
Assignee:
Becton, Dickinson and Company - Franklin Lakes NJ
International Classification:
A61B 5/145
US Classification:
600316, 600317, 600342
Abstract:
A device for sensing analyte concentration, and in particular glucose concentration, in vivo or in vitro is disclosed. A sensing element is attached to the distal end of an optical conduit, and comprises at least one binding protein adapted to bind with at least one target analyte. The sensing element further comprises at least one reporter group that undergoes a luminescence change with changing analyte concentrations. Optionally, the optical conduit and sensing element may be housed within a cannulated bevel.

Isbn (Books And Publications)

Intelligent Materials for Controlled Release

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Author

John DeNuzzio

ISBN #

0841235953

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John D Denuzzio from La Jolla, CA Get Report