John J Abrahams

7829377, Nov 9, 2010

Jan 11, 2006

11/329959

Robert C. Linares - Sherborn MA, US
Patrick J. Doering - Holliston MA, US
Bryant Linares - Sherborn MA, US
Alfred R. Genis - East Douglas MA, US
William W. Dromeshauser - Norwell MA, US
Michael Murray - Mountain View CA, US
Alicia E. Novak - Denver CO, US
John M. Abrahams - Scarsdale NY, US

Apollo Diamond, Inc - Framingham MA

H01L 21/00

438105, 438514, 438555, 438549

Masked and controlled ion implants, coupled with annealing or etching are used in CVD formed single crystal diamond to create structures for both optical applications, nanoelectromechanical device formation, and medical device formation. Ion implantation is employed to deliver one or more atomic species into and beneath the diamond growth surface in order to form an implanted layer with a peak concentration of atoms at a predetermined depth beneath the diamond growth surface. The composition is heated in a non-oxidizing environment under suitable conditions to cause separation of the diamond proximate the implanted layer. Further ion implants may be used in released structures to straighten or curve them as desired. Boron doping may also be utilized to create conductive diamond structures.

7854923, Dec 21, 2010

Sep 8, 2006

11/530362

Weiliam Chen - Mount Sinai NY, US
John M. Abrahams - Scarsdale NY, US

Endomedix, Inc. - Newark NJ

A61K 48/00
A61K 31/73

424 7027, 514 55, 514 2, 514 8

A tissue sealant for use in surgical and medical procedures for sealing the tissues of a living mammal is provided. The tissue sealant comprises a hydrogel which is formed by gelation of a premix disposed on the tissue to be sealed. The premix comprises alkylated chitosan or a gelatin, and a polybasic carboxylic acid or an oxidized polysaccharide, in an aqueous medium. The premix can also include a dehydrating reagent, a carboxyl activating reagent, or both. A specific use of the tissue sealant is in the repair of the dura mater after brain surgery to prevent leakage of cerebrospinal fluid. The tissue sealant may include a therapeutic or protective agent such as an antibiotic or an anti-inflammatory drug.

8513217, Aug 20, 2013

Sep 15, 2010

12/882624

Weiliam Chen - Mount Sinai NY, US
John M. Abrahams - Scarsdale NY, US

Endomedix, Inc. - Scarsdale NY

A61K 9/14
A61K 51/00

514 55, 514 2, 514 8, 514 54, 530351, 530395

A tissue sealant for use in surgical and medical procedures for sealing the tissues of a living mammal is provided. The tissue sealant comprises a hydrogel which is formed by gelation of a premix disposed on the tissue to be sealed. The premix comprises alkylated chitosan or a gelatin, and a polybasic carboxylic acid or an oxidized polysaccharide, in an aqueous medium. The premix can also include a dehydrating reagent, a carboxyl activating reagent, or both. A specific use of the tissue sealant is in the repair of the dura mater after brain surgery to prevent leakage of cerebrospinal fluid. The tissue sealant may include a therapeutic or protective agent such as an antibiotic or an anti-inflammatory drug.

8591856, Nov 26, 2013

Mar 29, 2006

11/277866

Patrick J. Doering - Holliston MA, US
Robert C. Linares - Wellifleet MA, US
Alicia E. Novak - Denver CO, US
John M. Abrahams - Scarsdale NY, US
Michael Murray - Mountain View CA, US

SCIO Diamond Technology Corporation - Greer SC

C30B 29/04

423446, 117 94, 117 95, 117104, 117 15, 117929

An electrolytic cell includes a container for holding an electrolyte. A conductively doped single crystal diamond anode electrode is positioned to be disposed within the electrolyte, as is a conductive cathode electrode. Conductors are coupled to the electrodes for coupling to a power supply. An electrolyte inlet and an electrolyte outlet are coupled to the container for causing electrolyte to flow past the electrodes. The anode electrode is downstream from the cathode electrode in one embodiment, such that an electrolyte comprising water is purified by generation of oxygen and/or ozone.

8636774, Jan 28, 2014

Dec 17, 2010

12/971620

John M. Abrahams - Scarsdale NY, US
Peter J. Amarosa - Dover NH, US
Michael Leatherman - Dover NH, US

Spinal USA, Inc. - Parsippany NJ

A61B 17/70

606250, 606249

An adjustable spinal implant device, comprising: a sliding portion provided with a tongue; and, a non-sliding portion provided with a slot adapted for receipt of the tongue; wherein the tongue is slidably and rotatably positioned within the slot.

20070031467, Feb 8, 2007

Jun 20, 2006

11/425280

John Abrahams - Scarsdale NY, US
Weiliam Chen - Mount Sinai NY, US

A61F 2/00

424423000

A therapeutic composition and a therapeutic method are provided for occlusion of a vascular site. The vascular site may be within a blood vessel or a lymph duct, and may include an aneurysm or an arteriovenous malformation, or may be in a normal section of the vessel or duct. A composition comprises an alkylated chitosan and a polybasic carboxylic acid or an oxidized polysaccharide in an aqueous medium. Another composition comprises a gelatin and an oxidized polysaccharide in an aqueous medium The composition is in the form of a substantially liquid sol immediately upon mixing, and gels or solidifies in situ in the vascular site. The method comprises introducing the composition as a sol into the interior of the vascular site, as with a catheter, wherein it gels in situ. The composition may further include a bioactive agent or a radiopaque agent or both.

20070031468, Feb 8, 2007

Jun 6, 2006

11/447794

John Abrahams - Scarsdale NY, US
Weiliam Chen - Mount Sinai NY, US

A61F 2/00

424423000

A therapeutic composition and a method are provided for occlusion of a vascular site. The vascular site may be within a blood vessel or a lymph duct, and may include an aneurysm, an arteriovenous malformation. The composition comprises an acrylated chitosan dissolved in an aqueous medium. The composition is preferably a flowable liquid at a pH of about 6-6.5, and gels or solidifies in situ in the vascular site at a physiological pH of about 6.9-7.4. The method comprises introducing the composition to the interior of the vascular site, as with a catheter. The composition may further include a bioactive agent or intact cells, or a radiopaque agent.

20070243130, Oct 18, 2007

Apr 18, 2006

11/379182

Weiliam Chen - Mount Sinai NY, US
John Abrahams - Scarsdale NY, US

A61K 51/00
A61K 48/00
A61K 38/18
A61K 9/14

424001110, 424488000, 514044000, 514012000

A tissue sealant for use in surgical and medical procedures for sealing the tissues of a living mammal is provided. The tissue sealant comprises a hydrogel which is formed by gelation of a premix disposed on the tissue to be sealed. The premix comprises an alkylated chitosan, a polybasic carboxylic acid, a dehydrating reagent, and a carboxyl activating reagent in an aqueous medium. A preferred use of the tissue sealant is in the repair of the dura mater after brain surgery to prevent leakage of cerebrospinal fluid. The tissue sealant may include a therapeutic or protective agent such as an antibiotic or an anti-inflammatory drug.