John S Abrahams

8636774, Jan 28, 2014

Dec 17, 2010

12/971620

John M. Abrahams - Scarsdale NY, US
Peter J. Amarosa - Dover NH, US
Michael Leatherman - Dover NH, US

Spinal USA, Inc. - Parsippany NJ

A61B 17/70

606250, 606249

An adjustable spinal implant device, comprising: a sliding portion provided with a tongue; and, a non-sliding portion provided with a slot adapted for receipt of the tongue; wherein the tongue is slidably and rotatably positioned within the slot.

20070031467, Feb 8, 2007

Jun 20, 2006

11/425280

John Abrahams - Scarsdale NY, US
Weiliam Chen - Mount Sinai NY, US

A61F 2/00

424423000

A therapeutic composition and a therapeutic method are provided for occlusion of a vascular site. The vascular site may be within a blood vessel or a lymph duct, and may include an aneurysm or an arteriovenous malformation, or may be in a normal section of the vessel or duct. A composition comprises an alkylated chitosan and a polybasic carboxylic acid or an oxidized polysaccharide in an aqueous medium. Another composition comprises a gelatin and an oxidized polysaccharide in an aqueous medium The composition is in the form of a substantially liquid sol immediately upon mixing, and gels or solidifies in situ in the vascular site. The method comprises introducing the composition as a sol into the interior of the vascular site, as with a catheter, wherein it gels in situ. The composition may further include a bioactive agent or a radiopaque agent or both.

20070031468, Feb 8, 2007

Jun 6, 2006

11/447794

John Abrahams - Scarsdale NY, US
Weiliam Chen - Mount Sinai NY, US

A61F 2/00

424423000

A therapeutic composition and a method are provided for occlusion of a vascular site. The vascular site may be within a blood vessel or a lymph duct, and may include an aneurysm, an arteriovenous malformation. The composition comprises an acrylated chitosan dissolved in an aqueous medium. The composition is preferably a flowable liquid at a pH of about 6-6.5, and gels or solidifies in situ in the vascular site at a physiological pH of about 6.9-7.4. The method comprises introducing the composition to the interior of the vascular site, as with a catheter. The composition may further include a bioactive agent or intact cells, or a radiopaque agent.

20080063617, Mar 13, 2008

Sep 7, 2006

11/470818

John M. Abrahams - Scarsdale NY, US
Weiliam Chen - Mount Sinai NY, US

A61K 8/73

424 7013

A cosmetic formulation containing an alkylated chitosan derivative, a polybasic carboxylic acid or an oxidized polysaccharide, and water, for moisturizing and/or softening skin is provided. The formulation is in the physical state of a viscous liquid or a gel, and when applied to skin, serves to moisturize and soften the skin. One embodiment of the formulation comprises PEG-chitosan and hyaluronic acid at a pH of about 3.5 to about 5.5. The formulation may be applied to skin as a bulk composition, on a towel or wipe, or in the form of a facial foam mask.

20080075657, Mar 27, 2008

Jul 30, 2007

11/830125

John Abrahams - Scarsdale NY, US
Weiliam Chen - Mount Sinai NY, US
Peter Zahos - Weston FL, US

A61K 51/00
A61K 38/18
A61K 9/14
A61K 48/00

424001110, 424488000, 514012000, 514044000

The invention provides a method of treating degenerative disc disease and discogenic pain by disposing a hydrogel tissue sealant within the intervertebral disc, where the hydrogel fills voids and tears in the annulus fibrosus and replaces leaked material from the nucleus pulposus. The hydrogel is formed in situ from a substantially liquid premix, which can be emplaced with a syringe needle or a catheter into the intervertebral disc, where it forms the hydrogel by gelation. The hydrogel can also include a therapeutic or a protective material, or a radiopaque or MRI-active agent to aid in visualization.

20090010982, Jan 8, 2009

Jun 10, 2008

12/136182

John M. Abrahams - Scarsdale NY, US
Weiliam Chen - Mount Sinai NY, US

Endomedix, Inc. - scarsdale NY

A61L 27/54
A61L 24/08
A61L 27/26

424422, 523118

A biocompatible adherent sheet for use in surgical and medical procedures for sealing the tissues of a living mammal is provided. The biocompatible adherent sheet includes a carrier sheet including a biocompatible polymer and a modified chitosan evenly disposed on one or both sides of the carrier sheet. Methods of preparing a biocompatible adherent sheet and methods of using a biocompatible adherent sheet are also provided. The biocompatible adherent sheet may also include a bioactive agent.

20120158069, Jun 21, 2012

Dec 17, 2010

12/971579

John M. Abrahams - Scarsdale NY, US
Peter J. Amarosa - Dover NH, US
Michael Leatherman - Dover NH, US

A61B 17/86

606305, 606104

A locking spring screw, comprising: a cylindrical screw body; a flexible spring member; and, a screw head attached to the cylindrical screw body, wherein the screw head comprises a tool slot adapted for receipt of the spring member, at least one outlet adjacent to the tool slot adapted for passage therethrough of a tongue of the spring member, and, a ridge located opposite the at least one outlet from the cylindrical screw body and at least partially around the circumference of the screw head.

20120323217, Dec 20, 2012

Jun 12, 2012

13/494582

John M. Abrahams - Scarsdale NY, US

A61M 25/10

604506

The present invention relates to a method and device for removing solid matter from a brain and controlling bleeding associated with the removal of the matter. The method involves securing a cranial anchor to a region of the skull in which an opening has been created to expose brain matter and introducing through a passage defined by the anchor a channel member that displaces brain tissue and exposes the solid matter. After removing the solid matter, a flowable hemostat is introduced into the cavity created by removal of the matter. A balloon introduced into the working channel is then inflated to compress the hemostat against the wall of the cavity to control bleeding from blood vessels around the cavity. The device includes a cranial anchor, a channel member defining a working channel, an optional removable trocar, and a catheter for introducing the hemostat and the inflatable balloon into the cavity.