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Joerg L Deerberg

from Columbus, NJ
Age ~60

Joerg Deerberg Phones & Addresses

  • 11 Irongate Ct, Columbus, NJ 08022 (609) 324-7603
  • 19 Rose Hill Dr, Bear, DE 19701 (302) 832-8966
  • 123 Presidential Dr, Wilmington, DE 19807
  • Greenville, DE
  • 991 Hayes Ave, Corvallis, OR 97330 (541) 752-0908

Publications

Us Patents

Asymmetric Catalytic Hydrogenation Process For Preparation Of Chiral Cyclic Beta-Aminoesters

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US Patent:
20040082795, Apr 29, 2004
Filed:
Sep 11, 2003
Appl. No.:
10/660345
Inventors:
Joerg Deerberg - Bear DE, US
Douglas McLeod - Kingston NJ, US
Tai-Yuen Yue - Bear DE, US
International Classification:
C07D277/18
C07D263/16
US Classification:
548/190000, 548/233000, 548/326500, 548/557000, 548/950000
Abstract:
A novel process for the asymmetric synthesis of substituted cyclic -amino-carboxylates of the type shown in the specification from appropriate -enamino-ester starting materials is described. These compounds are useful as intermediates for MMP and TACE inhibitors.

Process For The Preparation Of N-((1R,2S,5R)-5-(Tert-Butylamino)-2-((S)-3-(7-Tert-Butylpyrazolo[1,5-A][1,3,5]Triazin-4-Ylamino)-2-Oxopyrrolidin-1-Yl)Cyclohexyl)Acetamide

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US Patent:
20220177482, Jun 9, 2022
Filed:
Feb 22, 2022
Appl. No.:
17/677312
Inventors:
- Princeton NJ, US
Collin Chan - New York NY, US
Joerg Deerberg - Columbus NJ, US
Nathan R. Domagalski - Niantic CT, US
Martin D. Eastgate - Titusville NJ, US
Yu Fan - Highland Park NJ, US
Michael David Bengt Fenster - New York NY, US
Robert V. Forest - Hillsborough NJ, US
Rebecca A. Green - Metuchen NJ, US
Matthew R. Hickey - Yardley PA, US
Nathaniel David Kopp - Newtown PA, US
Thomas E. La Cruz - Flemington NJ, US
Kathleen Lauser - Minneapolis MN, US
Hong Geun Lee - Seoul, KR
David K. Leahy - Hightstown NJ, US
Helen Y. Luo - San Francisco CA, US
Thomas M. Razler - Yardley PA, US
Scott A. Savage - Yardley PA, US
Chris Sfouggatakis - Staten Island NY, US
Maxime C.D. Soumeillant - Princeton NJ, US
Serge Zaretsky - Fords NJ, US
Bin Zheng - Kendall Park NJ, US
Ye Zhu - Singapore, SG
International Classification:
C07D 487/04
Abstract:
The invention generally relates to an improved process for the preparation of N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide,

Process For The Preparation Of 6-(Cyclopropaneamido)-4-((2-Methoxy-3-(1-Methyl-1H-1,2,4-Triazol-3-Yl)Phenyl)Amino)-N-(Methyl-D3)Pyridazine-3-Carboxamide

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US Patent:
20210107897, Apr 15, 2021
Filed:
Dec 22, 2020
Appl. No.:
17/131718
Inventors:
- Princeton NJ, US
Joerg Deerberg - Columbus NJ, US
Dong Lin - Monmouth Junction NJ, US
Michael Dummeldinger - Plainsboro NJ, US
Bahar Inankur - New Brunswick NJ, US
Sergei Kolotuchin - Roselle Park NJ, US
Jun Li - Langhorne PA, US
Amanda J. Rogers - Asbury NJ, US
Victor W. Rosso - Monroe Township NJ, US
Eric M. Simmons - East Brunswick NJ, US
Maxime C.D. Soumeillant - Princeton NJ, US
Daniel S. Treitler - Cranford NJ, US
Jianji Wang - Dayton NJ, US
Bin Zheng - Kendall Park NJ, US
Michael J. Smith - Somerset NJ, US
Neil A. Strotman - Flemington NJ, US
Steven Tymonko - Lindenhurst IL, US
Tamas Benkovics - East Brunswick NJ, US
International Classification:
C07D 403/12
C07C 211/09
C07D 237/24
C07D 249/08
Abstract:
The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide of the formula:Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.

Process For The Preparation Of N-((1R,2S,5R)-5-(Tert-Butylamino)-2-((S)-3-(7-Tert-Butylpyrazolo[1,5-A][1,3,5]Triazin-4-Ylamino)-2-Oxopyrrolidin-1-Yl)Cyclohexyl)Acetamide

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US Patent:
20200223852, Jul 16, 2020
Filed:
Jul 19, 2018
Appl. No.:
16/631915
Inventors:
- Princeton NJ, US
Collin Chan - New York NY, US
Joerg Deerberg - Columbus NJ, US
Nathan R. Domagalski - Niantic CT, US
Martin D. Eastgate - Titusville NJ, US
Yu Fan - Highland Park NJ, US
Michael David Bengt Fenster - New York NY, US
Robert V. Forest - Hillsborough NJ, US
Rebecca A. Green - Metuchen NJ, US
Matthew R. Hickey - Yardley PA, US
Nathaniel David Kopp - Newtown PA, US
Thomas E. La Cruz - Flemington NJ, US
Kathleen Lauser - Minneapolis MN, US
Hong Geun Lee - Seoul, KR
David K. Leahy - Hightstown NJ, US
Helen Y. Luo - San Francisco CA, US
Thomas M. Razler - Yardley PA, US
Scott A. Savage - Yardley PA, US
Chris Sfouggatakis - Staten Island NY, US
Maxime C.D. Soumeillant - Princeton NJ, US
Serge Zaretsky - Fords NJ, US
Bin Zheng - Kendall Park NJ, US
Ye Zhu - Singapore, SG
International Classification:
C07D 487/04
Abstract:
The invention generally relates to an improved process for the preparation of N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolodin-1-yl)cyclohexyl)acetamide, as well as novel intermediates employed in the process, which may be useful for the treatment of cancer.

Process For The Preparation Of 6-(Cyclopropaneamido)-4-((2-Methoxy-3-(1-Methyl-1H-1,2,4-Triazol-3-Yl)Phenyl)Amino)-N-(Methyl-D3)Pyridazine-3-Carboxamide

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US Patent:
20200109134, Apr 9, 2020
Filed:
Mar 29, 2018
Appl. No.:
16/498442
Inventors:
- Princeton NJ, US
Joerg Deerberg - Columbus NJ, US
Dong Lin - Monmouth Junction NJ, US
Michael Dummeldinger - Plainsboro NJ, US
Bahar Inankur - New Brunswick NJ, US
Sergei Kolotuchin - Roselle Park NJ, US
Jun Li - Langhorne PA, US
Amanda J. Rogers - Asbury NJ, US
Victor W. Rosso - Monroe Township NJ, US
Eric M. Simmons - East Brunswick NJ, US
Maxime C.D. Soumeillant - Princeton NJ, US
Daniel S. Treitler - Cranford NJ, US
Jianji Wang - Dayton NJ, US
Bin Zheng - Kendall Park NJ, US
Michael J. Smith - Somerset NJ, US
Neil A. Strotman - Flemington NJ, US
Steven Tymonko - Lindenhurst IL, US
Tamas Benkovics - East Brunswick NJ, US
International Classification:
C07D 403/12
C07D 249/08
C07C 211/09
C07D 237/24
Abstract:
The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide of the formula: [INSERT CHEMICAL STRUCTURE HERE] Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.

Process For The Preparation Of 4-(8-(2-Chlorophenoxy)-[1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Bicyclo[2.2.1]Heptan-1-Ol And Novel Intermediates Therefor

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US Patent:
20160039813, Feb 11, 2016
Filed:
Aug 4, 2015
Appl. No.:
14/817352
Inventors:
- Princeton NJ, US
Keming Zhu - Somerset NJ, US
Joerg Deerberg - Columbus NJ, US
Wendy Wangying Yang - Plainsboro NJ, US
Kana Yamamoto - Toledo OH, US
Matthew R. Hickey - Yardley PA, US
International Classification:
C07D 471/04
C07C 51/29
C07D 213/77
C07C 29/00
C07C 35/29
C07C 61/13
Abstract:
A process is provided for preparing 4-(8-(2-chlorophenoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)bicyclo[2.2.1]heptan-1-ol and novel intermediates used in the process. The compound is a 11-beta hydroxysteroid dehydrogenase type I inhibitor which exhibits activity in the treatment of various metabolic diseases.
Joerg L Deerberg from Columbus, NJ, age ~60 Get Report