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Joao Incio Phones & Addresses

  • Cambridge, MA
  • Boston, MA

Work

Company: Portuguese american post-graduate society 2012 Address: North America Position: President

Languages

Spanish • French • English • Portuguese

Ranks

Description: Medicine

Industries

Research

Resumes

Resumes

Joao Incio Photo 1

Md; Phd Student At Mass General Hospital/Harvard Med School; President,Portuguese American Post-Graduate Society

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Position:
President at Portuguese American Post-Graduate Society, Visiting Phd Student at Massachusetts General Hospital/Harvard Medical School at Massachusetts General Hospital
Location:
Greater Boston Area
Industry:
Research
Work:
Portuguese American Post-Graduate Society - North America since 2012
President

Massachusetts General Hospital - Greater Boston Area since 2010
Visiting Phd Student at Massachusetts General Hospital/Harvard Medical School
Languages:
Spanish
French
English
Portuguese

Publications

Us Patents

Novel Compositions And Uses Of Metformin Agents

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US Patent:
20180064662, Mar 8, 2018
Filed:
Nov 25, 2015
Appl. No.:
15/555756
Inventors:
- Boston MA, US
- Waltham MA, US
Joao Incio - Boston MA, US
Peter Blume-Jensen - Waltham MA, US
Assignee:
THE GENERAL HOSPITAL CORPORATION - Boston MA
XTUIT PHARMACEUTICALS, INC. - Waltham MA
International Classification:
A61K 31/155
A61K 45/06
A61B 5/00
C07K 16/28
C07K 16/22
A61K 9/50
Abstract:
Methods and compositions for improving the delivery and/or efficacy of a therapy (e.g., an anti-cancer, anti-fibrotic or anti-inflammatory therapy) are disclosed. The invention is based, at least in part, on the discovery that metformin, a widely prescribed anti-diabetic drug, can affect the tumor microenvironment (e.g., directly, i.e., independent of its effects on cancer cells themselves or tumor metabolism). In embodiments described herein, metformin has been shown to reduce the amount of extracellular matrix, including collagen 1 and hyaluronan, in the fibro-inflammatory tumor microenvironment in a subject (e.g., a subject with a desmoplastic tumor).
Joao F Incio from Cambridge, MA, age ~41 Get Report