Search

Jinming Gu

from Newton, MA

Jinming Gu Phones & Addresses

  • 375 Pond Ave, Brookline, MA 02445
  • 101 Oldham Rd, West Newton, MA 02465
  • Newton, MA
  • 111 Acklen Park Dr, Nashville, TN 37203 (615) 269-7466
  • 141 Neese Dr, Nashville, TN 37211
  • Worcester, MA
  • Boston, MA

Work

Company: Abbott bioresearch center Mar 2009 Position: Sr. scientist ii

Education

School / High School: Vanderbilt University 1999 to 2005

Skills

Antibody Drug Development • Antibody and Protein Engineering • Hybridoma • Bi Specific Antibodies • Human Naive Library Phage Display • Yeast Display • Protein Chemistry • Antibody Drug Conjugate • Hts Assay Development • Protein Expression and Purification • Cancer Biology and Signaling • Oncology Drug In Vitro and In Vivo Screen • Tumor Xenograft Models • Flow Cytometry • Cell Line Generation • Molecular Cloning • Biochemistry • Cell Biology

Industries

Biotechnology

Resumes

Resumes

Jinming Gu Photo 1

Executive Director Of Biologics Discovery

View page
Location:
Brookline, MA
Industry:
Biotechnology
Work:
Abbott Bioresearch Center since Mar 2009
Sr. Scientist II
Education:
Vanderbilt University 1999 - 2005
East China University of Science and Technology
Skills:
Antibody Drug Development
Antibody and Protein Engineering
Hybridoma
Bi Specific Antibodies
Human Naive Library Phage Display
Yeast Display
Protein Chemistry
Antibody Drug Conjugate
Hts Assay Development
Protein Expression and Purification
Cancer Biology and Signaling
Oncology Drug In Vitro and In Vivo Screen
Tumor Xenograft Models
Flow Cytometry
Cell Line Generation
Molecular Cloning
Biochemistry
Cell Biology

Publications

Us Patents

Cell Cycle Phase Markers

View page
US Patent:
7612189, Nov 3, 2009
Filed:
Jul 22, 2005
Appl. No.:
11/572510
Inventors:
Suzanne Hancock - Cardiff, GB
Simon Stubbs - Cardiff, GB
Nicholas Thomas - Cardiff, GB
Ellen Fanning - Nashville TN, US
Jinming Gu - Boston MA, US
Assignee:
GE Healthcare UK Limited - Amersham
Vanderbilt University - Nashville TN
International Classification:
C07H 21/02
US Classification:
536 231
Abstract:
The present invention relates to polypeptide and nucleic acids constructs which are useful for determining the cell cycle status of a mammalian cell. Host cells transfected with these nucleic acid constructs can be used to determine the effects that test agents have upon the mammalian cell cycle.

Cell Cycle Reporting Cell Line

View page
US Patent:
7745123, Jun 29, 2010
Filed:
Jul 22, 2005
Appl. No.:
11/572516
Inventors:
Suzanne Hancock - Cardiff, GB
Simon Stubbs - Cardiff, GB
Nicholas Thomas - Cardiff, GB
Ellen Fanning - Nashville TN, US
Jinming Gu - Boston MA, US
Assignee:
GE Healthcare UK Limited - Cardiff
Vanderbilt University - Nashville TN
International Classification:
C12Q 1/68
US Classification:
435 6, 435325, 4352523, 4353201, 536 231
Abstract:
The present invention relates to non-destructive and dynamic means for determining the cell cycle position of living cells. The invention provides stable cell lines which can be used to determine the cell cycle position, together with methods for measuring the effect of a test agent on the cell cycle position.

Cell Cycle Phase Markers

View page
US Patent:
7897741, Mar 1, 2011
Filed:
Sep 16, 2009
Appl. No.:
12/560519
Inventors:
Suzanne Hancock - Cardiff, GB
Simon Stubbs - Cardiff, GB
Nicholas Thomas - Cardiff, GB
Ellen Fanning - Nashville TN, US
Jinming Gu - Boston MA, US
Assignee:
GE Healthcare UK Limited - Amersham
International Classification:
C07H 21/02
US Classification:
536 231
Abstract:
The present invention relates to polypeptide and nucleic acids constructs which are useful for determining the cell cycle status of a mammalian cell. Host cells transfected with these nucleic acid constructs can be used to determine the effects that test agents have upon the mammalian cell cycle.

Cell Cycle Markers

View page
US Patent:
20070212707, Sep 13, 2007
Filed:
Jul 22, 2005
Appl. No.:
11/572508
Inventors:
Suzanne Hancock - Cardiff, GB
Simon Stubbs - Cardiff, GB
Nicholas Thomas - Cardiff, GB
Ellen Fanning - Nashville TN, US
Jinming Gu - Boston MA, US
Assignee:
GE HEALTHCARE UK LIMITED - CARDIFF
VANDERBILT UNIVERSITY - NASHVILLE TN
International Classification:
C12Q 1/68
C07H 21/04
C12P 21/06
C07K 14/195
C12N 15/74
US Classification:
435006000, 435069100, 435252300, 435471000, 530350000, 536023700
Abstract:
The present invention relates to nucleic acid reporter constructs and host cells transfected with said constructs. The invention also relates to methods which are useful for determining the cell cycle status of a mammalian cell and for determining the effect of a test agent on the cell cycle position of a mammalian cell.

Regulation Of Cyclin D

View page
US Patent:
20110275697, Nov 10, 2011
Filed:
Feb 12, 2009
Appl. No.:
12/735738
Inventors:
Jinming Gu - Brookline MA, US
Assignee:
DANA FARBER CANCER INSTITUTE, INC. - BOSTON MA
International Classification:
A61K 31/713
G01N 33/53
A61P 35/00
C12Q 1/26
US Classification:
514 44 A, 435 25, 435 71
Abstract:
The present invention provides methods for modulating the level or activity of cyclin D by inhibiting EGLN2 expression or activity. The methods are particularly useful for treating or preventing a disorder associated with elevated cyclin D levels or activity, such as cancer.
Jinming Gu from Newton, MA Get Report