Inventors:
Martin M. Okun - Libertyville IL, US
Rebecca S. Hoffman - Wilmette IL, US
Thomas C. Harris - Gurnee IL, US
Parvez M. Mulani - Gurnee IL, US
Jingdong Chao - Lake Bluff IL, US
Talat Ashraf - Pleasanton CA, US
International Classification:
G06F 19/24
A61P 1/00
A61K 39/395
Abstract:
The invention provides methods, uses and compositions for the treatment of psoriasis or Crohn's disease. The invention describes methods and uses for treating psoriasis or Crohn's disease, wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to treat psoriasis in a subject. The invention includes methods of improving patient reported outcomes using a human human TNFα antibody, or antigen-binding portion thereof, for the treatment of Crohn's or psoriasis. The invention also provides methods of improving fatigue or depression in patients having Crohns'.