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Jerry R Mendell

from Columbus, OH
Age ~82
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Also known as:
Jerry Dr Mendell, Jerry Roy Mendell, Jerry Mendell Bus, Joyce N Mendell, Jerry P
Phone and address:
8176 Copperfield Dr, Columbus, OH 43235
(614) 888-7485
Related to:
Kurt Frederick Schmidt, 53Suzanne M Schmidt, 75Kathryn A Mendell, 48Joshua T Mendell, 50Thomas E Jenike, 55Gregory T Schmidt, 54Joyce N Mendell, 81Frederick J Schmidt, 82
Connected to:
Alan M Mendeloff, 66Albert I Mendeloff, 106Brett A Mendell, 51Courtney D Mendell, 49Diane M Mendell, 70Jared A Mendeloff, 37Lance Mendelow, 56Lawrence G Mendelowitz, 74Leroy J Mendell, 73Neil Mendeloff, 75

Jerry Mendell Phones & Addresses

  • 8176 Copperfield Dr, Columbus, OH 43235 (614) 888-7485 (614) 888-3687
  • 1654 Upham Dr, Columbus, OH 43210 (614) 293-4962
  • Worthington, OH
  • Hilton Head Island, SC
  • Beaufort, SC
  • 8176 Copperfield Dr, Columbus, OH 43235 (614) 888-7485

Work

Company: Nationwide Children's Hospital, Research II - Rm WA3011 Address: 700 Childrens Dr Suite Suite:, Columbus, OH 43205 Phones: (614) 722-2203

Education

School / High School: University Of Texas Southwestern Medical Center At Dallas 1966

Languages

English

Awards

Healthgrades Honor Roll

Ranks

Certificate: Neurology, 1972

Images

Emails

j***[email protected]

Specialities

Neurology • Neuropsychiatry (Neurology)

Professional Records

Medicine Doctors

Jerry Mendell Photo 1

Dr. Jerry R Mendell, Columbus OH - MD (Doctor of Medicine)

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Specialties:
Neurology
Neuropsychiatry (Neurology)
Address:
Nationwide Children's Hospital, Research II - Rm WA3011
700 Childrens Dr Suite Suite:, Columbus, OH 43205
(614) 722-2203 (Phone)
Certifications:
Neurology, 1972
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
Nationwide Children's Hospital, Research II - Rm WA3011
700 Childrens Dr Suite Suite:, Columbus, OH 43205

Wexner Medical Center at The Ohio State University
410 West 10Th Avenue, Columbus, OH 43210

James Cancer Hospital and Solove Research Institute
300 West 10Th Avenue, Columbus, OH 43210

Nationwide Children's Hospital
700 Children's Drive, Columbus, OH 43205
Education:
Medical School
University Of Texas Southwestern Medical Center At Dallas
Graduated: 1966
Medical School
Columbia Presby Med Center
Graduated: 1967
Medical School
National Institute Of Health
Graduated: 1970
Medical School
Ny Neur Institute
Graduated: 1969
Medical School
National Institute Of Health
Graduated: 1972
Jerry Mendell Photo 2

Jerry R. Mendell

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Specialties:
Child Neurology
Work:
Nationwide Childrens Hospital Neurology
700 Childrens Dr FL 5, Columbus, OH 43205
(614) 722-4625 (phone), (614) 722-4633 (fax)
Languages:
Chinese
English
Spanish
Description:
Dr. Mendell works in Columbus, OH and specializes in Child Neurology. Dr. Mendell is affiliated with Nationwide Childrens Hospital and OSU Harding Hospital.
Jerry Mendell Photo 3

Jerry R Mendell, Columbus OH

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Specialties:
Neurology
Pediatric Neurodevelopmental Disabilities
Work:
The Research Institute at Nationwide Children's Hospital
700 Childrens Dr, Columbus, OH 43205
The Ohio State University
1654 Upham Dr, Columbus, OH 43210
Education:
The University of Texas Southwestern (1966)
Jerry Mendell Photo 4

Jerry R Mendell, Columbus OH

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Specialties:
Neurologist
Address:
555 S 18Th St, Columbus, OH 43205
Education:
University of Texas, Southwestern Medical School (Dallas) - Doctor of Medicine
National Institutes of Health-Clinical Center - Fellowship - Neuromuscular Disorders
National Institutes of Health-Clinical Center - Residency - Neurology
New York State Psychiatric Institute - Residency - Neurology
Board certifications:
American Board of Psychiatry and Neurology Certification in Neurology (Psychiatry and Neurology)

Resumes

Resumes

Jerry Mendell Photo 5

Director Of Gene Therapy At Nationwide Childrens Hospital

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Location:
Columbus, Ohio Area
Industry:
Research
Experience:
Nationwide Childrens Hospital (Non-Profit; 5001-10,000 employees; Research industry): Director of Gene Therapy,  (-) 
Jerry Mendell Photo 6

Jerry Mendell

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Business Records

Name / Title
Company / Classification
Phones & Addresses
Jerry Roy Mendell
Jerry Mendell MD
Neurologist · Pediatric Neurologist
555 S 18 St, Columbus, OH 43205
(614) 722-3450
Jerry S. Mendell
President
Neuroscience Center Inc
General Hospital
1654 Upham Dr, Columbus, OH 43210
(614) 293-8930
Jerry R Mendell
NEUROMUSCULAR DISEASE CORPORATION
Worthington, OH

Publications

Isbn (Books And Publications)

Diagnosis and Management of Peripheral Nerve Disorders

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Author

Jerry R. Mendell

ISBN #

0195133013

Evaluation and Treatment of Myopathies

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Author

Jerry R. Mendell

ISBN #

0195152352

Evaluation and Treatment of Myopathies

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Author

Jerry R. Mendell

ISBN #

0803644108

Us Patents

Compositions And Methods For Treating Hepatic Neoplasia

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US Patent:
20110301226, Dec 8, 2011
Filed:
Dec 2, 2009
Appl. No.:
13/132783
Inventors:
Joshua T. Mendell - Dallas TX, US
Kathryn A. Mendell - Baltimore MD, US
Raghu R. Chivukula - Baltimore MD, US
Erik A. Wentzel - Leesburg VA, US
Jerry R. Mendell - Columbus OH, US
K. Reed Clark - Westerville OH, US
Janaiah Kota - Columbus OH, US
Assignee:
Nationwide Children's Hospital, Inc - Columbus OH
THE JOHNS HOPKINS UNIVERSITY - Baltimore MD
International Classification:
A61K 48/00
C12N 15/85
C12N 15/86
A61P 1/16
C12N 5/10
C12Q 1/68
A61P 35/00
C12N 5/09
C12N 15/861
US Classification:
514 44 R, 435375, 4353201, 435325, 435 611, 435 613
Abstract:
The present invention provides compositions and methods featuring miR-26 microRNA polynucleotides for the diagnosis, treatment or prevention of hepatic neoplasia.

Myostatin Inhibition For Enhancing Muscle And/Or Improving Muscle Function

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US Patent:
20100178348, Jul 15, 2010
Filed:
Nov 29, 2007
Appl. No.:
12/516995
Inventors:
Brian K. Kaspar - Westerville OH, US
Jerry R. Mendell - Columbus OH, US
Assignee:
Nationwide Children's Hospital - Columbus OH
International Classification:
A61K 9/14
A61K 35/76
C07H 21/00
C12N 7/01
C12N 5/071
C07H 21/04
A61P 21/00
US Classification:
424489, 424 932, 536 2372, 4352351, 435325
Abstract:
The present invention relates to methods for inhibiting myostatin, a regulator of muscle mass, for muscle enhancement (including inducing hypertrophy and/or hyperplasia) as well as improving muscle function (including decreasing atrophy and/or increasing endurance, force and/or strength). The methods involve delivering genes to cells using gene delivery in order to inhibit myostatin. Examples of genes to be delivered are genes encoding’ proteins such as Follistatin, Follistatin-related gene-1 (FLRG-I), growth differentiation factor associated protein-1 (GASP-I) and myostatin precursor propeptide. The genes are delivered using a recombinant Adeno-associated virus (rAAV) lacking rep and cap DNA capable of infecting the cells. Following introduction, the genes are expressed in the cell body of the infected cell and the encoded proteins are secreted systemically. In other methods-of the invention expression of proteins such as activin lib and myostatin is inhibited by oligonucleotide techniques to effect muscle enhancement. All the methods have applications in the treatment of musculoskeletal and neurodegenerative disorders among others, as well as enhancing muscle in livestock.

Adeno-Associated Virus Vector Delivery Of Muscle Specific Micro-Dystrophin To Treat Muscular Dystrophy

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US Patent:
20220364117, Nov 17, 2022
Filed:
Jun 3, 2022
Appl. No.:
17/832325
Inventors:
- Columbus OH, US
Jerry R. Mendell - Columbus OH, US
International Classification:
C12N 15/86
A61P 21/00
A61K 9/00
A61K 38/17
C12N 7/00
Abstract:
The invention provides gene therapy vectors, such as adeno-associated virus (AAV) vectors, expressing a miniaturized human micro-dystrophin gene and method of using these vectors to express micro-dystrophin in skeletal muscles including diaphragm and cardiac muscle and to protect muscle fibers from injury, increase muscle strength and reduce and/or prevent fibrosis in subjects suffering from muscular dystrophy.

Adeno-Associated Virus Vector Delivery Of Alpha-Sarcoglycan And The Treatment Of Muscular Dystrophy

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US Patent:
20220290180, Sep 15, 2022
Filed:
Aug 21, 2020
Appl. No.:
17/635978
Inventors:
- Columbus OH, US
Danielle Griffin - Canal Winchester OH, US
Jerry R. Mendell - Columbus OH, US
International Classification:
C12N 15/86
C07K 14/47
Abstract:
Described herein are methods of treating muscular dystrophy in a subject, comprising administration of a recombinant AAV vector AAVrh74.tMCK.hSCGA using a systemic route of administration and at a dose of about 1.0×10vg/kg to about 5.0×10vg/kg. Further disclosed are methods of expressing alpha-sarcoglycan gene in a cell or in a subject in need thereof, decreasing a serum CK level, and increasing alpha-sarcoglycan positive fibers in muscle tissue of a subject.

Adeno-Associated Virus Vector Delivery Of B-Sarcoglycan And Microrna-29 And The Treatment Of Muscular Dystrophy

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US Patent:
20220251156, Aug 11, 2022
Filed:
Jan 20, 2022
Appl. No.:
17/580228
Inventors:
- Columbus OH, US
Jerry R. Mendell - Columbus OH, US
International Classification:
C07K 14/47
A61K 48/00
C07K 14/705
C12N 15/86
A61P 25/14
A61P 21/00
C12N 15/85
Abstract:
Described herein are recombinant AAV vectors comprising a polynucleotide sequence comprising β-sarcoglycan and methods of using the recombinant vectors to reduce or prevent fibrosis in a mammalian subject suffering from a muscular dystrophy. Also described herein are combination therapies comprising administering AAV vector(s) expressing β-sarcoglycan and miR-29c to a mammalian subject suffering from a muscular dystrophy.

Adeno-Associated Virus Vector Delivery Of Microrna-29 To Treat Muscular Dystrophy

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US Patent:
20230001015, Jan 5, 2023
Filed:
Apr 12, 2022
Appl. No.:
17/719019
Inventors:
- Columbus OH, US
Jerry R. Mendell - Columbus OH, US
Kristin N. Heller - Columbus OH, US
International Classification:
A61K 48/00
C07K 14/47
A61K 38/17
A61K 31/7088
C12N 15/11
C12N 15/113
C12N 15/86
A61P 21/00
A61K 9/00
A61P 19/04
A61K 35/761
C12N 15/864
Abstract:
The invention provides for recombinant AAV vectors comprising a polynucleotide sequence comprising the guide strand of miR-29c and methods of using the recombinant vectors to reduce or prevent fibrosis in subjects suffering from muscular dystrophy.

Adeno-Associated Virus Vector Delivery Of Muscle Specific Micro-Dystrophin To Treat Muscular Dystrophy

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US Patent:
20210260218, Aug 26, 2021
Filed:
Jun 17, 2019
Appl. No.:
17/253956
Inventors:
- Columbus OH, US
Jerry R. Mendell - Columbus OH, US
International Classification:
A61K 48/00
C12N 15/86
C07K 14/47
A61P 21/00
Abstract:
The invention provides gene therapy vectors, such as adeno-associated vims (AAV) vectors, expressing a miniaturized human micro-dystrophin gene and method of using these vectors to express micro-dystrophin in skeletal muscle s including diaphragm and cardiac muscle and to protect muscle fibers from injury, increase muscle strength and reduce and/or prevent fibrosis in subjects suffering from muscular dystrophy.

Adeno-Associated Virus Vector Delivery Of Muscle Specific Micro-Dystrophin To Treat Muscular Dystrophy

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US Patent:
20210128749, May 6, 2021
Filed:
Mar 16, 2018
Appl. No.:
16/757207
Inventors:
- Columbus OH, US
Jerry R. Mendell - Columbus OH, US
International Classification:
A61K 48/00
C12N 15/86
A61P 21/00
Abstract:
The invention provides gene therapy vectors, such as adeno-associated vims (AAV) vectors, expressing a miniaturized human micro-dystrophin gene and method of using these vectors to express micro-dystrophin in skeletal muscle including diaphragm and cardiac muscle and to protect muscle fibers from injury, increase muscle strength and reduce and/or prevent fibrosis in subjects suffering from muscular dystrophy.
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Jerry R Mendell from Columbus, OH, age ~82 Get Report