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Jens J Birktoft

from New York, NY
Age ~83
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Also known as:
Jeans J Birktoft, Jens F
Phone and address:
350 Central Park W APT 9F, New York, NY 10025
(646) 408-4869
Connected to:
Andrew S Birky, 39Duane L Birky, 63Marty J Birky, 36Melissa A Birky, 53Patricia M Birky, 90Timothy D Birky, 59Todd K Birky, 52Darrell D Birl, 58Nisha B Birla, 47Diana C Birle, 56

Jens Birktoft Phones & Addresses

  • 350 Central Park W APT 9F, New York, NY 10025 (646) 408-4869
  • 836 Stephanie Dr, Caldwell, NJ 07006
  • 340 Kingsland St, Nutley, NJ 07110
  • Webster Groves, MO
  • 350 Central Park W APT 9F, New York, NY 10025

Work

Company: New york university Jan 2001 Position: Structural biologist/nanotechnologist

Education

Degree: post-grad School / High School: University of Cambridge 1967 to 1969 Specialities: structural biology

Skills

Protein Chemistry • Drug Discovery • Molecular Biology • Structural Biology • Dna • X Ray Crystallography • Biochemistry • Crystallography • Drug Design • Lifesciences • Research • Biotechnology • Bioinformatics • Protein Purification • Protein Engineering • Science • Life Sciences • Chemistry

Industries

Biotechnology

Resumes

Resumes

Jens Birktoft Photo 1

Director

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Location:
New York, NY
Industry:
Biotechnology
Work:
New York University since Jan 2001
Structural Biologist/Nanotechnologist
Xtal-Designs - New York City since Apr 1998
Director
Rutgers University 2000 - 2010
Structural Biologist/Consultant
Hoffmann-La Roche Jun 1993 - Apr 1998
Research Leader
Washington University School of Medicine Sep 1976 - Jun 1993
Faculty
Education:
University of Cambridge 1967 - 1969
post-grad, structural biology Københavns Universitet 1961 - 1967
cand. scient, Biochemistry Metropolitan Skolen 1954 - 1961
student, general science
Skills:
Protein Chemistry
Drug Discovery
Molecular Biology
Structural Biology
Dna
X Ray Crystallography
Biochemistry
Crystallography
Drug Design
Lifesciences
Research
Biotechnology
Bioinformatics
Protein Purification
Protein Engineering
Science
Life Sciences
Chemistry

Publications

Us Patents

Therapeutic Agents And Methods Of Use Thereof For The Modulation Of Angiogenesis

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US Patent:
6919307, Jul 19, 2005
Filed:
May 2, 2002
Appl. No.:
10/138935
Inventors:
Gary L. Olson - Mountainside NJ, US
Christopher Self - West Caldwell NJ, US
Lily Lee - Edison NJ, US
Charles Michael Cook - Mendham NJ, US
Jens Birktoft - New York NY, US
Assignee:
Praecis Pharmaceuticals, Inc. - Waltham MA
International Classification:
A61K031/336
A61K038/08
US Classification:
514 2, 514 16, 514475, 514478, 514588
Abstract:
The present invention provides methods of treating a parasitic infection, a lymphoid malignancy or an autoimmune disorder in a subject by administering to the subject a therapeutically effective amount of an angiogenesis inhibitor compound comprising a MetAP-2 inhibitory core coupled to a peptide.

Therapeutic Agents And Methods Of Use Thereof For The Modulation Of Angiogenesis

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US Patent:
7037890, May 2, 2006
Filed:
Oct 5, 2001
Appl. No.:
09/972772
Inventors:
Gary L. Olson - Mountainside NJ, US
Christopher Self - West Caldwell NJ, US
Lily Lee - Edison NJ, US
Charles Michael Cook - Mendham NJ, US
Jens Birktoft - New York NY, US
Assignee:
Praecis Pharmaceuticals, Inc. - Waltham MA
International Classification:
A61K 31/336
A61K 38/08
C07D 303/32
C07K 7/06
US Classification:
514 2, 514 16, 514475, 514478, 514588, 530300, 530329, 549332, 560157, 564 32
Abstract:
The present invention provides angiogenesis inhibitor compounds comprising a MetAP-2 inhibitory core coupled to a peptide, as well as pharmaceutical compositions comprising the angiogenesis inhibitor compounds and a pharmaceutically acceptable carrier. The present invention also provides methods of treating an angiogenic disease, e. g. , cancer, in a subject by administering to the subject a therapeutically effective amount of one or more of the angiogenesis inhibitor compounds of the invention.

Therapeutic Agents And Methods Of Use Thereof For The Modulation Of Angiogenesis

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US Patent:
7084108, Aug 1, 2006
Filed:
Nov 1, 2001
Appl. No.:
10/001945
Inventors:
Gary L. Olson - Mountainside NJ, US
Christopher Self - West Caldwell NJ, US
Lily Lee - Edison NJ, US
Charles Michael Cook - Mendham NJ, US
Jens Birktoft - New York NY, US
Barry Morgan - Franklin MA, US
Christopher C. Arico-Muendel - West Roxbury MA, US
Assignee:
Praecis Pharmaceuticals, Inc. - Waltham MA
International Classification:
A61K 31/336
A61K 38/08
C07D 303/32
C07K 7/06
US Classification:
514 2, 514 16, 514475, 514478, 514588, 530300, 530329, 549332, 560157, 564 32
Abstract:
The present invention provides angiogenesis inhibitor compounds comprising a MetAP-2 inhibitory core coupled to a peptide, as well as pharmaceutical compositions comprising the angiogenesis inhibitor compounds and a pharmaceutically acceptable carrier. The present invention also provides methods of treating an angiogenic disease, e. g. , cancer, in a subject by administering to the subject a therapeutically effective amount of one or more of the angiogenesis inhibitor compounds of the invention.

Methionine Aminopeptidase-2 Inhibitors And Methods Of Use Thereof

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US Patent:
7105482, Sep 12, 2006
Filed:
May 2, 2003
Appl. No.:
10/429174
Inventors:
Gary L. Olson - Mountainside NJ, US
Christopher Self - West Caldwell NJ, US
Lily Lee - Edison NJ, US
Charles Michael Cook - Mendham NJ, US
Jens Birktoft - New York NY, US
Barry Morgan - Franklin MA, US
Christopher C. Arico-Muendel - West Roxbury MA, US
Assignee:
Praecis Pharmaceuticals, Inc. - Waltham MA
International Classification:
A61K 31/336
A61K 38/08
US Classification:
514 2, 514 16, 514475, 514478, 514588
Abstract:
The present invention provides methods of treating, parasitic infections, thymoma, and lymphoid malignancies in a subject by administering to the subject a therapeutically effective amount of one or more of the compounds of the invention.

Therapeutic Agents And Methods Of Use Thereof For The Modulation Of Angiogenesis

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US Patent:
7157420, Jan 2, 2007
Filed:
Oct 8, 2004
Appl. No.:
10/962333
Inventors:
Gary L. Olson - Mountainside NJ, US
Christopher Self - West Caldwell NJ, US
Lily Lee - Edison NJ, US
Charles M. Cook - Mendham NJ, US
Jens Birktoft - New York NY, US
Barry Morgan - Franklin MA, US
Christopher C. Arico-Muendel - West Roxbury MA, US
Assignee:
Praecis Pharmaceuticals, Inc. - Waltham MA
International Classification:
A61K 31/336
A61K 38/08
US Classification:
514 2, 514 16, 514475, 514478, 514588
Abstract:
The present invention provides methods of treating an autoimmune disorder (e. g. , lupus erythematosus, multiple sclerosis, myasthenia gravis, vasculitis and diabetes mellitus) in a subject by administering to the subject a therapeutically effective amount of one or more compounds of the invention.

Methionine Aminopeptidase-2 Inhibitors And Methods Of Use Thereof

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US Patent:
7348307, Mar 25, 2008
Filed:
May 3, 2006
Appl. No.:
11/416622
Inventors:
Gary L. Olson - Mountainside NJ, US
Christopher Self - West Caldwell NJ, US
Lily Lee - New York NY, US
Charles M. Cook - Mendham NJ, US
Jens Birktoft - New York NY, US
Barry Morgan - Franklin MA, US
Christopher C. Arico-Muendel - West Roxbury MA, US
Assignee:
Praecis Pharmaceuticals Incorporated - Waltham MA
International Classification:
A61K 31/336
A61K 38/08
US Classification:
514 2, 514 16, 514475, 514478, 514588
Abstract:
The present invention provides methods of treating a lymphoma (e. g. , a T-cell lymphoma or a B-cell lymphoma) in a subject by administering to the subject a therapeutically effective amount of one or more of the compounds of the invention, for example, compounds of formulae I and XV:.

Therapeutic Agents And Methods Of Use Thereof For The Treatment Of Melanoma

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US Patent:
7405194, Jul 29, 2008
Filed:
Mar 24, 2006
Appl. No.:
11/388767
Inventors:
Gary L. Olson - Mountainside NJ, US
Christopher Self - West Caldwell NJ, US
Lily Lee - New York NY, US
Charles M. Cook - Mendham NJ, US
Jens Birktoft - New York NY, US
Barry Morgan - Franklin MA, US
Christopher C. Arico-Muendel - West Roxbury MA, US
Assignee:
Praecis Pharmaceuticals, Inc. - Waltham MA
International Classification:
A61K 31/336
A61K 38/08
US Classification:
514 2, 514 16, 514475, 514478, 514588
Abstract:
The present invention provides angiogenesis inhibitor compounds comprising a MetAP-2 inhibitory core coupled to a peptide, as well as pharmaceutical compositions comprising the angiogenesis inhibitor compounds and a pharmaceutically acceptable carrier. The present invention also provides methods of treating an angiogenic disease, e. g. , cancer, in a subject by administering to the subject a therapeutically effective amount of one or more of the angiogenesis inhibitor compounds of the invention.

Therapeutic Agents And Methods Of Use Thereof For The Modulation Of Angiogenesis

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US Patent:
7268111, Sep 11, 2007
Filed:
Sep 27, 2005
Appl. No.:
11/238152
Inventors:
Gary L. Olson - Mountainside NJ, US
Christopher Self - West Caldwell NJ, US
Lily Lee - New York NY, US
Charles M. Cook - Mendham NJ, US
Jens Birktoft - New York NY, US
Assignee:
Praecis Pharmaceuticals, Inc. - Waltham MA
International Classification:
A61K 31/336
A61K 38/08
C07D 303/32
C07K 7/06
US Classification:
514 2, 514 16, 514475, 514478, 514588, 530300, 530329, 549332, 560157, 564 32
Abstract:
The present invention provides angiogenesis inhibitor compounds comprising a MetAP-2 inhibitory core coupled to a peptide, as well as pharmaceutical compositions comprising the angiogenesis inhibitor compounds and a pharmaceutically acceptable carrier. The present invention also provides methods of treating an angiogenic disease, e. g. , cancer, in a subject by administering to the subject a therapeutically effective amount of one or more of the angiogenesis inhibitor compounds of the invention.
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Jens J Birktoft from New York, NY, age ~83 Get Report