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Jeannette Roberts Phones & Addresses

  • Averill Park, NY
  • Troy, NY
  • Watervliet, NY
  • Burnt Hills, NY
  • Liberty Township, OH
  • Hopewell Jct, NY
  • Binghamton, NY

Publications

Us Patents

Hydroxylated Contrast Enhancement Agents And Imaging Method

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US Patent:
20110243858, Oct 6, 2011
Filed:
Mar 31, 2011
Appl. No.:
13/077746
Inventors:
Brian James Grimmond - Clifton Park NY, US
Michael James Rishel - Saratoga Springs NY, US
Rong Zhang - Niskayuna NY, US
Jeannette Christine Roberts - Troy NY, US
Assignee:
GENERAL ELECTRIC COMPANY - Schenectady NY
International Classification:
A61K 49/10
A61K 49/00
A61P 43/00
US Classification:
424 936, 424 91
Abstract:
A method of diagnostic imaging is disclosed comprising administering a medical formulation to a subject, the formulation comprising a contrast enhancement agent having structure I and salts thereofwherein Ris independently at each occurrence a hydroxy group, a C-Chydroxyalkyl group, or a C-Calkyl group, and b is 0-4; R-Rare independently at each occurrence hydrogen, a C-Chydroxyalkyl group, or a C-Calkyl group, with the proviso that at least one of R-Ris a hydroxy group or a C-Chydroxyalkyl group; and wherein Q is one or more charge balancing counterions; and one or more pharmaceutically acceptable carriers and excipients. The subject is subjected to a diagnostic imaging technique such as magnetic resonance imaging. The technique may be used in a variety of diagnostic imaging regimes, such as imaging of circulatory systems, genitourinary systems, hepatobiliary systems, central nervous systems, tumors, and abscesses among others.

Contrast Enhancement Agents And Method Of Use Thereof

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US Patent:
20140086846, Mar 27, 2014
Filed:
Sep 26, 2012
Appl. No.:
13/626942
Inventors:
- Schenectady NY, US
Michael James Rishel - Saratoga Springs NY, US
Jeannette Christine Roberts - Burnt Hills NY, US
Assignee:
GENERAL ELECTRIC COMPANY - Schenectady NY
International Classification:
A61K 49/00
A61K 49/14
C07H 21/00
C07K 14/00
C07K 16/00
C07H 99/00
A61K 49/10
A61K 49/16
US Classification:
424 9321, 424 91, 424 932, 424 9322, 530402, 5303915, 536 187, 536 231
Abstract:
A contrast agent composition and a method of diagnostic imaging are provided. The composition comprises a pharmaceutically acceptable carrier and a metal-complex comprising a ligand having structure (XXX):wherein R, R, R, R, R, R′, R′, R′, R′ and R′ are selected form hydrogen, a protected C-Chydroxyalkyl group, or a C-Calkyl group; R, R′are selected from a hydrogen, a hydroxyl, a protected hydroxyl group, a protected C-Chydroxyalkyl group, a C-Calkyl group; n is an integer between 0 and 4; R, R′are selected from a hydrogen, a protecting group comprising C-Caliphatic radicals, C-Ccycloaliphatic radicals, C-Caromatic radicals, m is an integer between 1 and 10; at least one of Rand R′is acidic groups or protected acidic groups; Y comprises a protein or peptide moiety, a particle, a micelle, a liposome, an organic molecule, oligomer, polymer or a hydrophilic moiety.
Jeannette C Roberts from Averill Park, NY, age ~41 Get Report