Inventors:
Annmarie Sabb - Pennington NJ, US
Robert Vogel - Collingswood NJ, US
Gary Stack - Ambler PA, US
Deborah Evrard - Hamilton Square NJ, US
Amedeo Failli - Princeton Junction NJ, US
Lalitha Krishnan - Airmont NY, US
Anita Chan - Fort Lee NJ, US
Jianxin Ren - Nanuet NY, US
Charles Guinosso - Chestnut Ridge NY, US
Reinhardt Baudy - Hellertown PA, US
Jean Sze - Monmouth Junction NJ, US
Yanfang Li - Lawrenceville NJ, US
Charles Stanton - West New York NJ, US
Antonia Nikitenko - Tarrytown NY, US
International Classification:
C07D 491/02
C07D 209/82
C07D 333/50
US Classification:
546090000, 546080000, 548440000, 549041000
Abstract:
The present invention provides cycloalkylfused indole, benzothiophene, benzofuran, and indene derivatives, and methods for using them to, for example, treat, prevent and/or ameliorate central nervous system diseases by antagonizing 5-HTreceptors and modulating serotonin levels.