Jean Pierre Kinet

6602983, Aug 5, 2003

Sep 22, 1994

08/310902

Jean Pierre Kinet - Bethesda MD
Jarema Peter Kochan - Verona NJ

The United States of America as represented by the Department of Health and Human Services - Washington DC

C07K 14705

530350, 435 691, 536 235

A Polypeptide and DNA Sequence corresponding to the human receptor high affinity receptor for IgE as well as replicable microbial expression vehicles, transformed microorganisms, and cultures of microbial cells which produce this polypeptide.

7741335, Jun 22, 2010

Jun 28, 2002

10/482039

Alain Moussy - Paris, FR
Jean Pierre Kinet - Lexington MA, US

AB Science - Paris

A61K 31/505
A61K 31/517

514275, 5142661

The present invention relates to a method for treating inflammatory diseases such as rheumatoid arthritis (RA), comprising administering a tyrosine kinase inhibitor to a human in need of such treatment, more particularly a non-toxic, selective and potent c-kit inhibitor. Preferably, said inhibitor is unable to promote death of IL-3 dependent cells cultured in presence of IL-3.

20060204459, Sep 14, 2006

Sep 20, 2002

10/490286

Alain Moussy - Paris, FR
Jean Kinet - Lexington MA, US

A61K 8/49
A61K 31/506

424061000, 514252140

The present invention relates to a method for whitening human skin and treating melanocyte dysfunction associated diseases comprising administering a tyrosine kinase inhibitor to a human in need of such treatment, more particularly a non-toxic, selective and potent c-kit inhibitor. Preferably, said inhibitor is unable to promote death of IL-3 dependent cells cultured in presence of IL-3.

56396600, Jun 17, 1997

Feb 24, 1988

7/160457

Jean Pierre Kinet - Bethesda MD
Jarema Peter Kochan - Verona NJ

Hoffmann-La Roche Inc. - Nutley NJ
The United States of America as represented by the Department of Health
and Human Services - Washington DC

C12N 121
C12N 510
C12N 1512

4352523

A Polypeptide and DNA Sequence corresponding to the human receptor high affinity receptor for IgE as well as replicable microbial expression vehicles, transformed microorganisms, and cultures of microbial cells which produce this polypeptide.

57703965, Jun 23, 1998

Apr 16, 1992

7/869933

Jean Pierre Kinet - Bethesda MD

The United States of America as represented by the Department of Health
and Human Services - Washington DC

C12N 510
C12N 1512

435 691

The present invention relates to nucleic acid sequences, encoding amino acid sequences of the. alpha. ,. beta. , and. gamma. subunits of the high affinity receptor for immunoglobulin E, and for amino acid sequences of the subunits. The invention further relates to a method of producing the receptor by expressing cDNA for its. alpha. ,. beta. , and. gamma. subunits in a host cell simultaneously. Aspects of the invention are methods and compositions to inhibit the function of the human beta subunit, thereby treating or preventing allergic reactions.

61718033, Jan 9, 2001

Jun 23, 1998

9/103663

Jean Pierre Kinet - Bethesda MD

The United States Government as represented by the Department of Health and
Human Services - Washington DC

G01N 3353

435 71

The present invention relates to nucleic acid sequences, encoding amino acid sequences of the. alpha. ,. beta. , and. gamma. subunits of the high affinity receptor for immunoglobulin E, and for amino acid sequences of the subunits. The invention further relates to a method of producing the receptor by expressing cDNA for its. alpha. ,. beta. , and. gamma. subunits in a host cell simultaneously. Aspects of the invention are methods and compositions to inhibit the function of the human beta subunit, thereby treating or preventing allergic reactions.