Francis Lee - Yardley PA,
Feng Luo - Plainsboro NJ,
Jean Feyen - New Hope PA,
The present disclosure is directed to a method of treating bone metastasis, hypercalcemia, and/or bone resorption comprising administering to a patient in need thereof a therapeutically effective amount of a compound of formula (I)
or pharmaceutically acceptable salt, hydrate or solvate thereof.