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Jang B Rampal

from Yorba Linda, CA
Age ~77

Jang Rampal Phones & Addresses

  • 20470 Via Canarias, Yorba Linda, CA 92887 (714) 779-0075 (714) 773-7634
  • Arlington, VA
  • 1253 11Th St #2, Santa Monica, CA 90401 (714) 779-0075
  • Los Angeles, CA
  • 3419 Lake Arrowhead Ave, Fremont, CA 94555 (510) 487-2288
  • Union City, CA
  • Mc Lean, VA
  • Fullerton, CA
  • Pearl, MS
  • 20470 Via Canarias, Yorba Linda, CA 92887 (714) 779-0075

Work

Company: Quantiscientifics,llc Jun 2009 to Jul 2012 Position: Vice president, chemistry

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Indian Institute of Technology, Madras 1971 to 1975 Specialities: Organic Chemistry

Skills

Immunoassays • Chemistry • Diagnostics • Hardware Diagnostics

Industries

Biotechnology

Resumes

Resumes

Jang Rampal Photo 1

Consultant

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Location:
Yorba Linda, CA
Industry:
Biotechnology
Work:
Quantiscientifics,Llc Jun 2009 - Jul 2012
Vice President, Chemistry

Beckman Coulter Oct 1984 - Feb 2009
Senior Staff Scientist

Rampal Consulting Oct 1984 - Feb 2009
Consultant
Education:
Indian Institute of Technology, Madras 1971 - 1975
Doctorates, Doctor of Philosophy, Organic Chemistry
Dav Higher Secondary School, Amritsar
Skills:
Immunoassays
Chemistry
Diagnostics
Hardware Diagnostics

Publications

Us Patents

Immobilization Of Biopolymers To Aminated Substrates By Direct Adsorption

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US Patent:
6861214, Mar 1, 2005
Filed:
Oct 23, 2000
Appl. No.:
09/694701
Inventors:
Jang B. Rampal - Yorba Linda CA, US
Robert S. Matson - Orange CA, US
Assignee:
Beckman Coulter, Inc. - Fullerton CA
International Classification:
C12Q001/68
A61L009/00
B32B027/04
A62B007/08
B01J019/08
US Classification:
435 6, 422 5, 422 50, 422 61, 422 71, 422 88, 422 99, 422122, 422131, 422186
Abstract:
An assay article for detection biopolymers contained in a sample is described. The assay article includes a substrate and a biopolymer directly adsorbed on the surface of the substrate. A plurality of biopolymers may be adsorbed on the surface of the substrate to form an array. Also disclosed is a method of making the assay article. In the preferred method, an aminated polypropylene substrate is used. A biopolymer is contacted with the aminated substrate under a condition sufficient for direct adsorption of the biopolymer on the surface of the substrate. A method of detecting a target biopolymer contained in a sample is also disclosed. In this method, a substrate is contacted with either a probe or target biopolymer under a condition sufficient for a direct adsorption of either the probe or target biopolymer on the substrate to form a probe assay article or a target assay article. Then, the probe assay article is contacted with the target biopolymer, or the target assay article is contacted with the probe biopolymer under a condition that allows the formation of a probe-target complex. Finally, the complex is detected and the presence of the complex is used as a measurement for the presence or the amount of the biopolymer target contained in the sample.

Multiplex Hybridization System For Identification Of Pathogenic And Method Of Use

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US Patent:
7271781, Sep 18, 2007
Filed:
Mar 1, 2001
Appl. No.:
10/220212
Inventors:
Steven H. Fischer - Rockville MD, US
Jang B. Rampal - Yorba Linda CA, US
Gary A. Fahle - Silver Spring MD, US
Patricia S. Conville - Rockville MD, US
Assignee:
The United States of America as Represented by the Secretary of the Department of Health and Human Services - Washington DC
Beckman Coulter, Inc. - Fullerton CA
International Classification:
C12Q 1/68
US Classification:
345 6, 435 912
Abstract:
A method for species-specific identification of a species is provided. Also disclosed is a method for identifying the species of present in a sample. A device is disclosed for the detection of -specific oligonucleotides are also disclosed, as are kits.

Immobilization Of Biomolecules On Substrates By Attaching Them To Adsorbed Bridging Biomolecules

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US Patent:
20040029156, Feb 12, 2004
Filed:
May 1, 2003
Appl. No.:
10/427658
Inventors:
Robert Matson - Orange CA, US
Jang Rampal - Yorba Linda CA, US
Assignee:
Beckman Coulter, Inc.
International Classification:
B05D003/00
C12Q001/68
C12M001/34
US Classification:
435/006000, 435/287200, 427/002110
Abstract:
An assay article for detection first biomolecules contained in a sample is described. The assay article includes a substrate having a modified surface and a first biomolecule directly adsorbed and immobilized on the modified surface of the substrate without linking moieties. A second biomolecule is bound to or adsorbed on the first biomolecule. Also disclosed is a method of making the assay article. A first biomolecule (other than an adhesive protein) is contacted with a modified surface of a substrate. The substrate is dried to directly adsorb the first biomolecule and immobilize it on the modified surface of the substrate without additional fixing steps to form an activated substrate. Then, a second biomolecule is contacted with the activated substrate under conditions sufficient for the first biomolecule to bind the second biomolecule.

Immunosorbent Assay In Microarray Format

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US Patent:
20040049351, Mar 11, 2004
Filed:
Aug 28, 2002
Appl. No.:
10/230028
Inventors:
Robert Matson - Orange CA, US
Jang Rampal - Yorba Linda CA, US
International Classification:
C12Q001/68
G01N033/53
G06F019/00
G01N033/48
G01N033/50
US Classification:
702/019000, 435/006000, 435/007100
Abstract:
A multiplexed immunosorbent assay can be performed in a microarray format on a plate. Capture molecules corresponding to the specific analytes are printed onto the bottom of the wells of chemically activated plates. The conditions are optimized for printing in terms of capture molecule spot density (mass and uniformity), coupling conditions, and blocking conditions. Samples containing analytes to be detected are delivered to the wells, allowed to incubate for a specific time after which unbound sample is removed by rinsing. Detection secondary capture molecules are pre-mixed and delivered to each well. Following incubation and rinse, signal generation reagents are added and the signals are detected.

Immobilization Of Biopolymers To Aminated Substrates By Direct Adsorption

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US Patent:
20050123986, Jun 9, 2005
Filed:
Jan 20, 2005
Appl. No.:
11/040735
Inventors:
Jang Rampal - Yorba Linda CA, US
Robert Matson - Orange CA, US
International Classification:
B05D003/00
C12Q001/68
C12M001/34
US Classification:
435006000, 435287200, 427002110
Abstract:
An assay article for detection biopolymers contained in a sample is described. The assay article includes a substrate and a biopolymer directly adsorbed on the surface of the substrate. A plurality of biopolymers may be adsorbed on the surface of the substrate to form an array. Also disclosed is a method of making the assay article. In the preferred method, an aminated polypropylene substrate is used. A biopolymer is contacted with the aminated substrate under a condition sufficient for direct adsorption of the biopolymer on the surface of the substrate. A method of detecting a target biopolymer contained in a sample is also disclosed. In this method, a substrate is contacted with either a probe or target biopolymer under a condition sufficient for a direct adsorption of either the probe or target biopolymer on the substrate to form a probe assay article or a target assay article. Then, the probe assay article is contacted with the target biopolymer, or the target assay article is contacted with the probe biopolymer under a condition that allows the formation of a probe-target complex. Finally, the complex is detected and the presence of the complex is used as a measurement for the presence or the amount of the biopolymer target contained in the sample.

Chemiluminescent Generated Fluorescent Labeling

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US Patent:
20070037174, Feb 15, 2007
Filed:
Aug 12, 2005
Appl. No.:
11/203073
Inventors:
Jang Rampal - Yorba Linda CA, US
Robert Matson - Orange CA, US
International Classification:
C12Q 1/68
G01N 33/53
US Classification:
435006000, 435007500
Abstract:
A method for detecting a target analyte in a sample having the steps of: binding the target analyte to a solid substrate; binding a reporter to the bound target to form a label enzyme; contacting a chemiluminescent reagent with the label enzyme to produce a fluorescent precipitate; and detecting fluorescence from the fluorescent precipitate.

Capillary Electrophoretic System For Separation Of Samples Containing Both Positively And Negatively Charged Components

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US Patent:
54663512, Nov 14, 1995
Filed:
Mar 31, 1995
Appl. No.:
8/414684
Inventors:
Sushma Rampal - Yorba Linda CA
Jang B. Rampal - Yorba Linda CA
James C. Osborne - Orange CA
Assignee:
Beckman Instruments, Inc. - Fullerton CA
International Classification:
G01N 2726
G01N 27447
US Classification:
2041801
Abstract:
A sample having both positively and negatively charged components may be separated during the same run by injecting a plug of sample at both ends of the capillary and applying an electric field in the capillary, where there is insufficient electroosmotic flow in the capillary to reverse sample migration direction, such as in the case of a gel-filled column.

Oligonucleotide Repeat Arrays

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US Patent:
59811854, Nov 9, 1999
Filed:
May 28, 1997
Appl. No.:
8/863639
Inventors:
Robert S. Matson - Orange CA
Peter J. Coassin - San Juan Capistrano CA
Jang B. Rampal - Yorba Linda CA
Charles Thomas Caskey - Houston TX
Assignee:
Beckman Coulter, Inc. - Fullerton CA
International Classification:
C12Q 168
C07H 2102
C07H 2100
US Classification:
435 6
Abstract:
A solid support based hybridization assay is provided which allows for the systematic and reproducible analysis of repeat and tandem repeat oligonucleotide sequences of DNA and RNA by hybridization to a reverse dot blot array comprising strings of such repeats complementary to those found in particular nucleic acid targets (e. g. , analyte PCR product). An addressable library (i. e. , an indexed set) of complementary repeats is synthesized on a suitable support. Preferably, the support comprises a low fluorescent background support, thereby facilitating the use of non-radioisotopic modes of detection (such as fluorescence or chemiluminescence); particularly suitable in this regard is an aminated polypropylene support or similar material. Preferred arrays permit screening of DNA and RNA samples for complete sets of particular types of nucleotide repeat sequences (e. g. , all nucleotide doublet or triplet repeats).
Jang B Rampal from Yorba Linda, CA, age ~77 Get Report