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Jane V Gunson

from Redwood City, CA
Age ~63
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Related to:
Dorothy I Kurtz, 99Melissa V Johnson, 59Sarah Murray, 50Martin Johnson, 72Patricia Johnson, 64
Connected to:
David S Gunson, 77Elizabeth F Gunson, 60Greg A Gunson, 69Jonathan D Gunson, 38Richard A Gunson, 85Jacalyn J Gunstad, 72Peter A Gunston, 50William L Gunstream, 72Leena Guntakandla, 45Ramareddy Guntaka, 84

Jane Gunson Phones & Addresses

  • 911 Fulton St, Redwood City, CA 94061 (650) 369-5639
  • 1458 Hudson St, Redwood City, CA 94061
  • 886 Mule Deer Cir, South Lake Tahoe, CA 96150
  • Menlo Park, CA
  • San Mateo, CA
  • El Dorado, CA

Publications

Us Patents

Harvest Operations For Recombinant Proteins

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US Patent:
20140080180, Mar 20, 2014
Filed:
Mar 14, 2013
Appl. No.:
13/826166
Inventors:
Richard St. John - Millbrae CA, US
Jane V. Gunson - Redwood City CA, US
Kim Kaleas - San Mateo CA, US
Deepa Nadarajah - San Mateo CA, US
Rachel Adams - Guelph, CA
Bradley R. Snedecor - Portola Valley CA, US
Assignee:
GENENTECH, INC. - South San Francisco CA
International Classification:
C12P 21/00
C07K 16/00
US Classification:
435 696, 435 691
Abstract:
The present invention contemplates methods of producing a recombinant protein comprising fermenting a prokaryotic host cell wherein said prokaryotic host cell has been transformed with a nucleic acid encoding said recombinant protein, harvesting said recombinant protein under conditions where dOlevels are greater than 0%, purifying said recombinant protein to a filtered bulk, wherein said filtered bulk does not contain detectable DHNA-recombinant protein adduct, as measured by an IEC assay at 310 nm. Furthermore, method of producing a recombinant protein comprising fermenting a menE gene-deleted prokaryotic host cell wherein said prokaryotic host cell has been transformed with a nucleic acid encoding said recombinant protein, harvesting said recombinant protein, purifying said recombinant protein to a filtered bulk, wherein said filtered bulk does not contain detectable DHNA-recombinant protein adduct, as measured by an IEC assay at 310 nm, wherein the recombinant protein yield is increased by about 20% or greater is contemplated.

Harvest Operations For Recombinant Proteins

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US Patent:
20230069966, Mar 9, 2023
Filed:
Jul 13, 2022
Appl. No.:
17/864255
Inventors:
- South San Francisco CA, US
Richard ST. JOHN - Millbrae CA, US
Jane V. GUNSON - Redwood City CA, US
Kimberly KALEAS - San Mateo CA, US
Deepa NADARAJAH - San Mateo CA, US
Rachel L.E. ADAMS - Guelph CA, US
Bradley R. SNEDECOR - Portola Valley CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C12P 21/00
C07K 16/00
Abstract:
The present invention contemplates a method of producing a recombinant protein comprising (a) fermenting a prokaryotic host cell wherein said prokaryotic host cell has been transformed with a nucleic acid encoding said recombinant protein, and (b) harvesting said recombinant protein under conditions where dO levels are greater than 0%, and (c) purifying said recombinant protein to a filtered bulk, wherein said filtered bulk does not contain detectable DHNA-recombinant protein adduct, as measured by an IEC assay at 310 nm. The present invention also contemplates a method of producing a recombinant protein comprising (a) fermenting a menE gene-deleted prokaryotic host cell wherein said prokaryotic host cell has been transformed with a nucleic acid encoding said recombinant protein, (b) harvesting said recombinant protein; and (c) purifying said recombinant protein to a filtered bulk, wherein said filtered bulk does not contain detectable DHNA-recombinant protein adduct, as measured by an IEC assay at 310 nm, and wherein the recombinant protein yield is increased by about 20% or greater.

Harvest Operations For Recombinant Proteins

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US Patent:
20200199639, Jun 25, 2020
Filed:
Feb 7, 2019
Appl. No.:
16/270494
Inventors:
- South San Francisco CA, US
Richard ST. JOHN - Millbrae CA, US
Jane V. GUNSON - Redwood City CA, US
Kimberly KALEAS - San Mateo CA, US
Deepa NADARAJAH - San Mateo CA, US
Rachel L.E. ADAMS - Guelph, CA
Bradley R. SNEDECOR - Portola Valley CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C12P 21/00
C07K 16/00
Abstract:
The present invention contemplates a method of producing a recombinant protein comprising (a) fermenting a prokaryotic host cell wherein said prokaryotic host cell has been transformed with a nucleic acid encoding said recombinant protein, and (b) harvesting said recombinant protein under conditions where dOlevels are greater than 0%, and (c) purifying said recombinant protein to a filtered bulk, wherein said filtered bulk does not contain detectable DHNA-recombinant protein adduct, as measured by an IEC assay at 310 nm. The present invention also contemplates a method of producing a recombinant protein comprising (a) fermenting a menE gene-deleted prokaryotic host cell wherein said prokaryotic host cell has been transformed with a nucleic acid encoding said recombinant protein, (b) harvesting said recombinant protein; and (c) purifying said recombinant protein to a filtered bulk, wherein said filtered bulk does not contain detectable DHNA-recombinant protein adduct, as measured by an IEC assay at 310 nm, and wherein the recombinant protein yield is increased by about 20% or greater.

Harvest Operations For Recombinant Proteins

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US Patent:
20180291411, Oct 11, 2018
Filed:
Feb 28, 2018
Appl. No.:
15/908526
Inventors:
- South San Francisco CA, US
Richard ST. JOHN - Millbrae CA, US
Jane V. GUNSON - Redwood City CA, US
Kimberly KALEAS - San Mateo CA, US
Deepa NADARAJAH - San Mateo CA, US
Rachel L.E. ADAMS - Guelph, CA
Bradley R. SNEDECOR - Portola Valley CA, US
International Classification:
C12P 21/00
C07K 16/00
Abstract:
The present invention contemplates a method of producing a recombinant protein comprising (a) fermenting a prokaryotic host cell wherein said prokaryotic host cell has been transformed with a nucleic acid encoding said recombinant protein, and (b) harvesting said recombinant protein under conditions where dOlevels are greater than 0%, and (c) purifying said recombinant protein to a filtered bulk, wherein said filtered bulk does not contain detectable DHNA-recombinant protein adduct, as measured by an IEC assay at 310 nm. The present invention also contemplates a method of producing a recombinant protein comprising (a) fermenting a menE gene-deleted prokaryotic host cell wherein said prokaryotic host cell has been transformed with a nucleic acid encoding said recombinant protein, (b) harvesting said recombinant protein; and (c) purifying said recombinant protein to a filtered bulk, wherein said filtered bulk does not contain detectable DHNA-recombinant protein adduct, as measured by an IEC assay at 310 nm, and wherein the recombinant protein yield is increased by about 20% or greater.

Harvest Operations For Recombinant Proteins

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US Patent:
20160130624, May 12, 2016
Filed:
Jun 9, 2015
Appl. No.:
14/734848
Inventors:
- South San Francisco CA, US
Richard ST. JOHN - Millbrae MA, US
Jane V. GUNSON - Redwood City CA, US
Kimberly KALEAS - San Mateo CA, US
Deepa NADARAJAH - San Mateo CA, US
Rachel L.E. ADAMS - Guelph, CA
Bradley R. SNEDECOR - Portola Valley CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C12P 21/00
C07K 16/00
Abstract:
The present invention contemplates a method of producing a recombinant protein comprising (a) fermenting a prokaryotic host cell wherein said prokaryotic host cell has been transformed with a nucleic acid encoding said recombinant protein, and (b) harvesting said recombinant protein under conditions where dOlevels are greater than 0%, and (c) purifying said recombinant protein to a filtered bulk, wherein said filtered bulk does not contain detectable DHNA-recombinant protein adduct, as measured by an IEC assay at 310 nm. The present invention also contemplates a method of producing a recombinant protein comprising (a) fermenting a menE gene-deleted prokaryotic host cell wherein said prokaryotic host cell has been transformed with a nucleic acid encoding said recombinant protein, (b) harvesting said recombinant protein; and (c) purifying said recombinant protein to a filtered bulk, wherein said filtered bulk does not contain detectable DHNA-recombinant protein adduct, as measured by an IEC assay at 310 nm, and wherein the recombinant protein yield is increased by about 20% or greater.

Harvest Operations For Recombinant Proteins

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US Patent:
20150225760, Aug 13, 2015
Filed:
Sep 26, 2014
Appl. No.:
14/497964
Inventors:
- South San Francisco CA, US
Richard ST. JOHN - Millbrae CA, US
Jane V. GUNSON - Redwood City CA, US
Kimberly KALEAS - San Mateo CA, US
Deepa NADARAJAH - San Mateo CA, US
Rachel L E ADAMS - Guelph, CA
Bradley R. SNEDECOR - Portola Valley CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C12P 21/00
C07K 16/00
Abstract:
The present invention contemplates methods of producing a recombinant protein comprising fermenting a prokaryotic host cell wherein said prokaryotic host cell has been transformed with a nucleic acid encoding said recombinant protein, harvesting said recombinant protein under conditions where dOlevels are greater than 0%, purifying said recombinant protein to a filtered bulk, wherein said filtered bulk does not contain detectable DHNA-recombinant protein adduct, as measured by an IEC assay at 310 nm. Furthermore, method of producing a recombinant protein comprising fermenting a menE gene-deleted prokaryotic host cell wherein said prokaryotic host cell has been transformed with a nucleic acid encoding said recombinant protein, harvesting said recombinant protein, purifying said recombinant protein to a filtered bulk, wherein said filtered bulk does not contain detectable DHNA-recombinant protein adduct, as measured by an IEC assay at 310 nm, wherein the recombinant protein yield is increased by about 20% or greater is contemplated.
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Jane V Gunson from Redwood City, CA, age ~63 Get Report