US Patent:
20070059257, Mar 15, 2007
Inventors:
David Estrada - Jersey City NJ, US
Benjamin Fitz - Brooklyn NY, US
Jan Macik - Clark NJ, US
Neil Napolitano - Fanwood NJ, US
Alfred Smetana - Wayne NJ, US
Joseph Synodis - Summit NJ, US
Michael Trama - River Vale NJ, US
International Classification:
A61K 8/21
A61K 8/46
Abstract:
A composition for the treatment of sensitive teeth comprising a suitable carrier and a desensitizing amount of: a) at least one tubule blocking agent preferably a combination of two such agents; and b) a nerve desensitizing agent selected from the group consisting of at least one potassium salt at least one strontium salt and mixtures thereof wherein the tubule blocking agent deposits or swells upon the dentinal surface and/or precipitates within the dentinal tubules retaining a higher concentration of the nerve desensitizing agent at the exposed dentinal surface and within the dentinal tubules The compositions may further contain a source of physiologically acceptable fluoride ion such as stannous fluoride Also disclosed are methods of using the subject compositions in the treatment of sensitive teeth.