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James M Pachence

from Bradenton, FL
Age ~71

James Pachence Phones & Addresses

  • 4754 Mainsail Dr, Bradenton, FL 34208
  • Wailea, HI
  • Princeton, NJ
  • Naperville, IL
  • 18 Elm St, Hopewell, NJ 08525 (609) 466-8058
  • Lawrence Township, NJ
  • Newtown, PA
  • Monmouth Junction, NJ
  • Manasota, FL

Work

Company: Southern lights na Position: President/ceo

Education

Degree: Ph.D. School / High School: University of Pennsylvania 1975 to 1980 Specialities: Biophysics

Skills

Medical Devices • Product Development • Oncology • Entrepreneurship • New Business Development • Biotechnology • Commercialization • Business Development • Start Ups • Cancer • Marketing Strategy • Infectious Diseases • Clinical Trials • Pharmaceutical Industry • Marketing • Mergers and Acquisitions • Orthopedic • Management • Venture Capital • Market Research • Fda • Market Development • Program Management • Fundraising • Product Launch • Drug Delivery • Lifesciences • Surgery • Biopharmaceuticals • Vaccines

Languages

Italian

Industries

Medical Devices

Public records

Vehicle Records

James Pachence

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Address:
4754 Mainsail Dr, Bradenton, FL 34208
Phone:
(609) 466-8058
VIN:
1FMCU9DG7BKC27766
Make:
FORD
Model:
ESCAPE
Year:
2011

Resumes

Resumes

James Pachence Photo 1

Chief Scientific Officer

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Location:
4754 Mainsail Dr, Bradenton, FL 34208
Industry:
Medical Devices
Work:
Southern Lights NA
President/CEO

The Rotary Club of Princeton since Jul 2010
President

Augmenta Biologicals since Aug 2009
Consultant

LifeScienc since Jul 2009
CSO

Nucryst Pharmaceuticals 2008 - 2009
Consultant
Education:
University of Pennsylvania 1975 - 1980
Ph.D., Biophysics
Skills:
Medical Devices
Product Development
Oncology
Entrepreneurship
New Business Development
Biotechnology
Commercialization
Business Development
Start Ups
Cancer
Marketing Strategy
Infectious Diseases
Clinical Trials
Pharmaceutical Industry
Marketing
Mergers and Acquisitions
Orthopedic
Management
Venture Capital
Market Research
Fda
Market Development
Program Management
Fundraising
Product Launch
Drug Delivery
Lifesciences
Surgery
Biopharmaceuticals
Vaccines
Languages:
Italian

Business Records

Name / Title
Company / Classification
Phones & Addresses
James M. Pachence
Manager
The Serious Foodie
Food & Beverages
4754 Mainsail Dr, Bradenton, FL 34208
James Pachence
VIRIUM PHARMACEUTICALS INC
James Pachence 116 Vlg Blvd STE 200, Princeton, NJ 08540
116 Vlg Blvd STE 200, Princeton, NJ 08540

Publications

Us Patents

Polymeric Conjugates For Tissue Activated Drug Delivery

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US Patent:
20040228831, Nov 18, 2004
Filed:
May 15, 2003
Appl. No.:
10/437983
Inventors:
Benjamin Belinka - Kendall Park NJ, US
James Pachence - Hopewell NJ, US
Jose Rosa - Lawrenceville NJ, US
Paul Simon - Wilmington DE, US
International Classification:
A61K038/43
US Classification:
424/078270, 424/094100
Abstract:
The present invention relates to a polymeric drug conjugate with one or more biologically active agents conjugated via an enzymatically cleavable linker to either a regular repeating linear unit comprising a water soluble polymer segment and a multifunctional chemical moiety, or a branched polymer comprising two or more water soluble polymer segments each bound to a common multifunctional chemical moiety, as well as to methods of making such conjugates. The present invention is also directed to pharmaceutical compositions comprising such conjugates and to the use of such conjugates to treat pathological conditions.

Multi-Stage Collagen-Based Template Or Implant For Use In The Repair Of Cartilage Lesions

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US Patent:
60801948, Jun 27, 2000
Filed:
Feb 10, 1995
Appl. No.:
8/385290
Inventors:
James M. Pachence - Hopewell NJ
Sally Frenkel - Flushing NY
David Menche - New York NY
Assignee:
The Hospital for Joint Disease Orthopaedic Institute - New York NY
International Classification:
A61F 230
US Classification:
623 18
Abstract:
The invention is a template to aid in the regeneration of articular cartilage. The template is formed by combining a porous collagen sponge ("collagen matrix") with a dense collagen membrane. The dense collagen membrane is placed on the surface of the cartilage defect to prevent cell migration from the subchondral plate and vasculature. The collagen membrane will allow movement and exchange of fluids, nutrients, cytokines and other factors necessary for cartilage regeneration. The collagen matrix has been developed to allow attachment and growth of cells, specifically chondrocytes which are normally found in articular cartilage. The collagen matrix can be combined with chondrocytes in vitro, and therefore serve to transport cultured cells to the defect site and to retain the cells in position following implantation. Procedures are described to effectively use the two-staged template, and to fix the template to the repair site.

Process For Extracting Type I Collagen Form An Avian Source, And Applications Therefor

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US Patent:
51380307, Aug 11, 1992
Filed:
Oct 10, 1989
Appl. No.:
7/419496
Inventors:
James M. Pachence - Lawrenceville NJ
International Classification:
A23J 110
C07K 302
C07K 1506
US Classification:
530356
Abstract:
A process for extracting type I collagen from an avian source such as poultry feet that incorporates a fibrillar mass of connective tissue as well as bony tissue to yield a collagen product having useful medical and biotechnology applications. In this process, after being cleaned and decontaminated, the poultry feet are comminuted and then enzyme-treated to enhance the yield. The enzyme-treated comminuted material which is rich in collagen is dispersed in an organic acid to cause the fibrillar mass to undergo controlled swelling, after which the mass is separated from the bony tissue and purified to remove non-collangenous material. The purified mass is dried to provide the desired Type I collagen product which may be ground into a powder or formed into a collagen matrix or sponge, depending on the end use therefor.

Collagen Matrix Beads For Soft Tissue Repair

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US Patent:
48372854, Jun 6, 1989
Filed:
Sep 8, 1987
Appl. No.:
7/093826
Inventors:
Richard A. Berg - Lambertville NJ
Frederick H. Silver - Bangor PA
James M. Pachence - Lawrenceville NJ
Assignee:
MediMatrix - Princeton NJ
International Classification:
C08H 106
A23J 110
A61K 3702
US Classification:
530356
Abstract:
Collagen-based compositions for augmenting soft tissue, wound dressings, implants, injectable formulations or other drug delivery systems, comprising resorbable collagen matrix beads, the beads having an average pore size of from 50 to 350 microns, and the collagen comprising from 1 to 30% by volume of the beads, the collagen matrix being sufficiently open to stimulate cellular ingrowth therethrough and yet sufficiently stiff and non-compressible to fill and protect a wound, and the formulation being sufficiently moisture and gas permeable to prevent liquid pooling on a wound and to permit sufficient oxygen diffusion for promoting wound healing.

Collagen Matrix/Polymer Film Composite Dressing

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US Patent:
48419621, Jun 27, 1989
Filed:
Sep 11, 1987
Appl. No.:
7/095779
Inventors:
Richard A. Berg - Lambertville NJ
Frederick H. Silver - Bangor PA
James M. Pachence - Lawrenceville NJ
John D'Antonio - Princeton NJ
International Classification:
A61L 1500
US Classification:
128156
Abstract:
A wound dressing comprising a crosslinked collagen matrix; a bioabsorbable adhesive coated on one surface of the collagen matrix; a multilayer polymer film imparting pre-selected moisture vapor and gas transmissivity to the dressing, secured to the opposite surface of the collagen matrix; and an adhesive securing the collagen matrix to the polymer film.

Methods And Products For Sealing A Fluid Leak In A Tissue

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US Patent:
6183498, Feb 6, 2001
Filed:
Sep 20, 1999
Appl. No.:
9/180687
Inventors:
Dale P. Devore - Chelmsford MA
Charles Putnam - Belle Meade NJ
James M. Pachence - Hopewell NJ
International Classification:
A61B 1704
A61K 3817
US Classification:
606214
Abstract:
Methods and products for rapidly sealing a fluid leak in a tissue are provided. A polymerizable protein is applied to a tissue having an opening which creates a fluid leak in the tissue, in order to seal the opening. The tissue area and opening coated with the polymerizable protein are exposed to an initiator in order to polymerize the covering in situ, and create a seal over the opening that prevents fluid leakage. The methods and products to the invention may be used, for example, to seal airholes in lung injuries and to seal anastomoses and suture lines for blood vessels.

Fixation Method For The Attachment Of Wound Repair Materials To Cartilage Defects

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US Patent:
57133743, Feb 3, 1998
Filed:
Feb 10, 1995
Appl. No.:
8/386799
Inventors:
James M. Pachence - Hopewell NJ
Sally Frenkel - Flushing NY
David Menche - New York NY
Assignee:
The Hospital for Joint Diseases Orthopaedic Institute - New York NJ
International Classification:
A61B 1900
US Classification:
128898
Abstract:
An attachment method to hold a biomaterial in place until healing occurs. The method consists of anchoring sutures through the subchondral plate into bony tissue with at least two lines emerging from the surface. The anchored suture lines are then pulled through the implant at its four quadrants, and is thus used to secure the cartilage repair material into the wound site.

Method Of Bonding Collagen To Fibers, Particularly Dacron

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US Patent:
51571110, Oct 20, 1992
Filed:
May 2, 1991
Appl. No.:
7/694729
Inventors:
James M. Pachence - Lawrenceville NJ
International Classification:
C07K 308
US Classification:
530356
Abstract:
A method of bonding collagen to synthetic polyester fibers, particularly DACRON. The method involves providing synthetic polyester fabric fibers having repeating carbonyl groups, hydrogenating the repeating carbonyl groups and then conducting a transesterification step which includes the addition of free amine groups. The free amine groups are reacted with a bifunctional crosslinking agent to produce modified polyester fibers. The final step involves adding collagen to the modified polyester fibers for a time sufficient to produce covalent bonding of the collagen to the fibers. The invention also involves the making of a fabric matrix comprised of synthetic polyester fibers, particularly DACRON, and collagen being covalently bound to the fibers. Such matrix can be utilized in ligament prosthesis design.
James M Pachence from Bradenton, FL, age ~71 Get Report