Search

James Hoffman Phones & Addresses

  • 248 E 9Th Ave, Conshohocken, PA 19428 (610) 834-8075
  • 145 S Kingscroft Dr, Bear, DE 19701
  • Philadelphia, PA
  • Newark, DE
  • 104 Lombard St, Philadelphia, PA 19147 (215) 829-4474

Work

Position: Executive, Administrative, and Managerial Occupations

Education

Degree: Bachelor's degree or higher

Emails

Professional Records

Real Estate Brokers

James Hoffman Photo 1

James Hoffman, Conshohocken PA Agent

View page
Work:
Coldwell Banker
Conshohocken, PA
(215) 327-6010 (Phone)

Medicine Doctors

James Hoffman Photo 2

James Hoffman

View page
Specialties:
Hematology/Oncology
Work:
Sylvester Comprehensive Cancer Center Hematology
1475 NW 12 Ave STE 3300, Miami, FL 33136
(305) 243-6102 (phone), (305) 243-9161 (fax)
Education:
Medical School
Albert Einstein College of Medicine at Yeshiva University
Graduated: 2002
Procedures:
Bone Marrow Biopsy
Chemotherapy
Electrocardiogram (EKG or ECG)
Lumbar Puncture
Conditions:
Hodgkin's Lymphoma
Leukemia
Multiple Myeloma
Non-Hodgkin's Lymphoma
Acne
Languages:
English
Description:
Dr. Hoffman graduated from the Albert Einstein College of Medicine at Yeshiva University in 2002. He works in Miami, FL and specializes in Hematology/Oncology. Dr. Hoffman is affiliated with Jackson Memorial Hospital, Sylvester Comprehensive Cancer Center, University Of Miami Hospital and VA Medical Center-Miami.
James Hoffman Photo 3

James D. Hoffman

View page
Specialties:
Orthopaedic Surgery, Orthopedic Sports Medicine
Work:
Treasure Coast Center For Surgery
1155 SE Monterey Rd Ext, Stuart, FL 34994
(772) 286-8028 (phone), (772) 283-6628 (fax)

South Florida Orthopedics & Sports MedicineSouth Florida Orthopaedics & Sports Medicine
1050 SE Monterey Rd STE 400, Stuart, FL 34994
(772) 288-2400 (phone), (772) 419-0144 (fax)
Education:
Medical School
University of Miami, Miller School of Medicine
Graduated: 1996
Procedures:
Arthrocentesis
Hip Replacement
Hip/Femur Fractures and Dislocations
Joint Arthroscopy
Knee Replacement
Spinal Surgery
Knee Arthroscopy
Lower Arm/Elbow/Wrist Fractures and Dislocations
Occupational Therapy Evaluation
Shoulder Surgery
Conditions:
Fractures, Dislocations, Derangement, and Sprains
Osteoarthritis
Internal Derangement of Knee
Internal Derangement of Knee Cartilage
Internal Derangement of Knee Ligaments
Languages:
English
Spanish
Description:
Dr. Hoffman graduated from the University of Miami, Miller School of Medicine in 1996. He works in Stuart, FL and 1 other location and specializes in Orthopaedic Surgery and Orthopedic Sports Medicine. Dr. Hoffman is affiliated with Martin Health System South and Martin Medical Center.
James Hoffman Photo 4

James K. Hoffman

View page
Specialties:
Orthopaedic Surgery, Orthopedic Sports Medicine
Work:
Coordinated Health
2775 Schoenersville Rd STE 4, Bethlehem, PA 18017
(610) 861-8080 (phone), (610) 861-0258 (fax)

Coordinated Health
505 Independence Rd STE A, East Stroudsburg, PA 18301
(570) 420-8080 (phone), (570) 420-1704 (fax)

Coordinated Health
3100 Emrick Blvd, Bethlehem, PA 18020
(610) 515-8080 (phone), (610) 997-5762 (fax)

Coordinated Health
115 Switzgabel Dr, Brodheadsville, PA 18322
(877) 247-8080 (phone), (570) 402-3066 (fax)
Education:
Medical School
Hahnemann University School of Medicine
Graduated: 1990
Procedures:
Arthrocentesis
Hallux Valgus Repair
Knee Arthroscopy
Lower Arm/Elbow/Wrist Fractures and Dislocations
Lower Leg Amputation
Shoulder Arthroscopy
Shoulder Surgery
Spinal Surgery
Carpal Tunnel Decompression
Hip Replacement
Hip/Femur Fractures and Dislocations
Joint Arthroscopy
Knee Replacement
Conditions:
Rotator Cuff Syndrome and Allied Disorders
Fractures, Dislocations, Derangement, and Sprains
Hallux Valgus
Internal Derangement of Knee
Internal Derangement of Knee Cartilage
Languages:
English
Spanish
Description:
Dr. Hoffman graduated from the Hahnemann University School of Medicine in 1990. He works in Brodheadsville, PA and 3 other locations and specializes in Orthopaedic Surgery and Orthopedic Sports Medicine. Dr. Hoffman is affiliated with Coordinated Health Orthopedic Hospital, Lehigh Valley Hospital 17Th Street, Lehigh Valley Hospital Cedar Crest and Sacred Heart Hospital.
James Hoffman Photo 5

James K. Hoffman

View page
Specialties:
Family Medicine
Work:
Salinas Family Practice
1328 Natividad Rd, Salinas, CA 93906
(831) 757-8081 (phone), (831) 757-0625 (fax)
Education:
Medical School
University of California, Irvine School of Medicine
Graduated: 1977
Procedures:
Arthrocentesis
Circumcision
Destruction of Benign/Premalignant Skin Lesions
Destruction of Lesions on the Anus
Electrocardiogram (EKG or ECG)
Hearing Evaluation
Pulmonary Function Tests
Skin Tags Removal
Vaccine Administration
Vasectomy
Conditions:
Abdominal Hernia
Abnormal Vaginal Bleeding
Acne
Acute Bronchitis
Acute Conjunctivitis
Languages:
English
Spanish
Description:
Dr. Hoffman graduated from the University of California, Irvine School of Medicine in 1977. He works in Salinas, CA and specializes in Family Medicine. Dr. Hoffman is affiliated with Salinas Valley Memorial Healthcare System.
James Hoffman Photo 6

James E. Hoffman

View page
Specialties:
Pediatrics, Adolescent Medicine
Work:
Saint Francis Cape Physician Associates Specialty
3250 Gordonville Rd STE 301, Cape Girardeau, MO 63703
(573) 334-9641 (phone), (573) 331-4130 (fax)
Education:
Medical School
Philadelphia College of Osteopathic Medicine
Graduated: 1975
Procedures:
Circumcision
Destruction of Benign/Premalignant Skin Lesions
Electrocardiogram (EKG or ECG)
Hearing Evaluation
Pulmonary Function Tests
Vaccine Administration
Conditions:
Abdominal Hernia
Acute Bronchitis
Acute Conjunctivitis
Acute Otitis Externa
Acute Pharyngitis
Languages:
English
Spanish
Description:
Dr. Hoffman graduated from the Philadelphia College of Osteopathic Medicine in 1975. He works in Cape Girardeau, MO and specializes in Pediatrics and Adolescent Medicine. Dr. Hoffman is affiliated with Saint Francis Medical Center and Southeast Hospital.
James Hoffman Photo 7

James S. Hoffman

View page
Specialties:
Gastroenterology
Work:
Hawthorn Medical Associates LLC
535 Faunce Cor Rd, North Dartmouth, MA 02747
(508) 996-3991 (phone), (508) 961-2533 (fax)
Education:
Medical School
Boston University School of Medicine
Graduated: 1988
Procedures:
Colonoscopy
Sigmoidoscopy
Upper Gastrointestinal Endoscopy
Electrocardiogram (EKG or ECG)
Vaccine Administration
Conditions:
Anal Fissure
Celiac Disease
Cholelethiasis or Cholecystitis
Chronic Pancreatitis
Cirrhosis
Languages:
English
Portuguese
Spanish
Description:
Dr. Hoffman graduated from the Boston University School of Medicine in 1988. He works in Dartmouth, MA and specializes in Gastroenterology. Dr. Hoffman is affiliated with St Lukes Hospital.
James Hoffman Photo 8

James S. Hoffman

View page
Specialties:
Anesthesiology
Work:
Northside Anesthesia ServicesNorthside Anesthesia Services LLC
13500 N Meridian St, Carmel, IN 46032
(317) 567-2180 (phone), (800) 731-0751 (fax)

Northside Anesthesia ServicesNorthside Anesthesia Services LLC
2001 W 86 St, Indianapolis, IN 46260
(317) 566-1000 (phone), (317) 566-1700 (fax)

Northside Anesthesia Services
8501 Harcourt Rd, Indianapolis, IN 46260
(317) 567-2179 (phone), (317) 471-4441 (fax)

Northside Anesthesia Services
8081 Township Line Rd, Indianapolis, IN 46260
(317) 415-8180 (phone)

Northside Anesthesia ServicesNorthside Anesthesia Services LLC
8111 Township Line Rd, Indianapolis, IN 46260
(317) 705-5050 (phone), (800) 731-0751 (fax)
Education:
Medical School
Indiana University School of Medicine
Graduated: 1984
Languages:
English
Description:
Dr. Hoffman graduated from the Indiana University School of Medicine in 1984. He works in Carmel, IN and 4 other locations and specializes in Anesthesiology. Dr. Hoffman is affiliated with Saint Vincent Womens Hospital, St Vincent Carmel Hospital and St Vincent Indianapolis Hospital & Heart Center.
James Hoffman Photo 9

James A. Hoffman

View page
Specialties:
Plastic Surgery
Work:
James A Hoffman MD
1875 Woodwinds Dr STE 240, Saint Paul, MN 55125
(651) 686-4548 (phone), (651) 501-5843 (fax)
Education:
Medical School
University of Wisconsin Medical School
Graduated: 1989
Languages:
English
Description:
Dr. Hoffman graduated from the University of Wisconsin Medical School in 1989. He works in Woodbury, MN and specializes in Plastic Surgery. Dr. Hoffman is affiliated with Lakeview Hospital, North Memorial Medical Center and Woodwinds Health Campus.

Lawyers & Attorneys

James Hoffman Photo 10

James Stephen Hoffman - Lawyer

View page
Licenses:
Dist. of Columbia - Active 2008
James Hoffman Photo 11

James Robert Hoffman - Lawyer

View page
Licenses:
Virginia - Authorized to practice law 2005
James Hoffman Photo 12

James Hoffman - Lawyer

View page
Office:
Law Offices of James P. Hoffman
Specialties:
Personal Injury
Workers' Compensation Law
Corporate Law
ISLN:
906436200
Admitted:
1967
University:
University of Northern Iowa, B.A., 1966
Law School:
University of Iowa, J.D., 1967
James Hoffman Photo 13

James Hoffman - Lawyer

View page
ISLN:
1000198934
Admitted:
2005
James Hoffman Photo 14

James Hoffman - Lawyer

View page
ISLN:
913692187
Admitted:
1975
University:
North Park College, B.A., 1968
Law School:
John Marshall Law School, J.D., 1975
James Hoffman Photo 15

James Hoffman - Lawyer

View page
Office:
Prime Grp. Realty Tr.
Specialties:
Real Estate
Corporate Law
ISLN:
906436248
Admitted:
1987
University:
University of Illinois, B.S., 1984; University of Illinois, B.S., 1984
Law School:
Harvard University, J.D., 1987
James Hoffman Photo 16

James Hoffman - Lawyer

View page
ISLN:
1000799572
Admitted:
2017
James Hoffman Photo 17

James Hoffman - Lawyer

View page
Office:
Bush, Motto, Creen, Koury & Halligan, P.L.C.
Specialties:
Personal Injury
Civil Litigation
Family Law
ISLN:
906436262
Admitted:
1973
University:
University of Iowa, B.A., 1969
Law School:
University of Iowa, J.D., 1973

License Records

James Hoffman

License #:
MT033582T - Expired
Category:
Medicine
Type:
Graduate Medical Trainee

James David Hoffman

License #:
MT011406T - Expired
Category:
Medicine
Type:
Graduate Medical Trainee

James P Hoffman

Address:
Conshohocken, PA 19428
License #:
RS176443L - Active
Category:
Real Estate Commission
Type:
Real Estate Salesperson-Standard

James T Hoffman

Address:
Philadelphia, PA 19117
License #:
CA022941L - Expired
Category:
Accountancy
Type:
Certified Public Accountant

Resumes

Resumes

James Hoffman Photo 18

James Hoffman Oceanside, CA

View page
Work:
RJT COMPUQUEST
Irvine, CA
May 2011 to Nov 2012
DIRECTOR, BUSINESS DEVELOPMENT, NET NEW ACCOUNTS

OCTAGON RESEARCH SOLUTIONS
Wayne, PA
Jul 2010 to May 2011
DIRECTOR, BUSINESS DEVELOPMENT, STRATEGIC ACCOUNTS

SPARTA SYSTEMS

Jan 2009 to Jul 2010
Senior Account Executive - Quality Management

QUMAS INC

Jan 2008 to Jan 2009
Senior Account Executive - Quality Management

OPEN TEXT CORPORATION

Jul 2005 to Dec 2008
Director of Sales - Life Sciences West

BEARINGPOINT CONSULTING
Irvine, CA
Dec 2003 to Jul 2005
Business Development Manager - Life Sciences West

ORACLE CORPORATION
Irvine, CA
Oct 1998 to Dec 2003
Account Manager - General Business and Life Sciences West

Education:
Northern Arizona University
Flagstaff, AZ
1984
BS in Business Management

James Hoffman Photo 19

James Hoffman Oceanside, CA

View page
Work:
RJT COMPUQUEST
Irvine, CA
May 2011 to Nov 2012
DIRECTOR, BUSINESS DEVELOPMENT, NET NEW ACCOUNTS

OCTAGON RESEARCH SOLUTIONS
Wayne, PA
Jul 2010 to May 2011
DIRECTOR, BUSINESS DEVELOPMENT, STRATEGIC ACCOUNTS

SPARTA SYSTEMS

Jan 2009 to Jul 2010
Senior Account Executive - Quality Management

QUMAS INC

Jan 2008 to Jan 2009
Senior Account Executive - Quality Management

OPEN TEXT CORPORATION

Jul 2005 to Dec 2008
Director of Sales - Life Sciences West

BEARINGPOINT CONSULTING
Irvine, CA
Dec 2003 to Jul 2005
Business Development Manager - Life Sciences West

ORACLE CORPORATION
Irvine, CA
Oct 1998 to Dec 2003
Account Manager - General Business and Life Sciences West

Education:
Northern Arizona University
Flagstaff, AZ
1984
BS in Business Management

James Hoffman Photo 20

James Hoffman Runnemede, NJ

View page
Work:
Fantastic Finish Remodeling
Sicklerville, NJ
Jan 2007 to Jan 2012
Home Remodeling Specialist

Harcourt Inc
Bellmawr, NJ
Jan 2007 to Jan 2007
Full Case Inductor

Barton Jeep
Spokane, WA
2006 to 2007
Lot Technician, Service Department

Appleway Automotive Group
Spokane, WA
2004 to 2006
Lead Lot Technician, Sales Department

Spokesman's-Review
Spokane, WA
2004 to 2004
Newspaper Courier

Education:
TRITON REGIONAL HIGH SCHOOL
Runnemede, NJ
Jun 2002
Diploma

James Hoffman Photo 21

James Hoffman Ardmore, PA

View page
Work:
GlaxoSmithKline
Collegeville, PA
2002 to 2011
Principal Scientist, Antibiotic Chemistry Discovery Performance Unit (DPU), US R&D

3-DIMENSIONAL PHARMACEUTICALS
Exton, PA
1996 to 2002
Research Scientist

GROUP SYNDETIC
Berwyn, PA
1995 to 1996
Project Manager

JOHNSON MATTHEY PHARMACEUTICAL SERVICES
West Deptford, NJ
1994 to 1995
Business Development Analyst

MERCK RESEARCH LABORATORIES
West Point, PA
1989 to 1994
Staff Chemist

NATIONAL INSTITUTES OF HEALTH, BETHESDA
Frederick, MD
1987 to 1989
Research Scientist

Education:
Saint Joseph's University
Philadelphia, PA
May 1992
Master of Business Administration

Dickinson College
Carlisle, PA
May 1987
Bachelor of Science in Chemistry

Business Records

Name / Title
Company / Classification
Phones & Addresses
Mr. James Hoffman
President
Classic Die Services, Inc.
Wire Products. Tool & Die Makers Equipment & Supplies. Tool & Die Makers
6926 Trafalgar Drive, Suite D, Fort Wayne, IN 46803-4206
(260) 748-6907, (260) 748-6907
James Hoffman
Director Medical Services
Martek Biosciences Corp
Drugs, Drug Proprietaries, and Druggists' Sun...
104 E Main St, Lansdale, PA 19446
James L. Hoffman
Owner
Hoffman Refrigeration
Plumbing/Heating/Air Cond Contractor
17 Malvina Ln, Newark, DE 19713
(302) 737-6939
James Hoffman
President
Jts Custom Builders
Single-Family Home and Commercial Construction and Remodeling
1216 Mays Lndg Rd, Elm, NJ 08037
(609) 567-4271
James Hoffman
Owner
Kagista Janitorial Svc
Janitor Service
(907) 543-2939
James Hoffman
Principal
Mill Road Construction Co
General Contractor
1295 Bobarn Dr, Penn Valley, PA 19072
(610) 667-7330
James D. Hoffman
Chairman, Chief Executive Offi, President
Earle M. Jorgensen Company
Whol Steel & Aluminum Products · Metals Service Center Mfg Sheet Metalwork Mfg Fabricated Plate Wrk · Metals Service Center
(847) 301-6100, (330) 425-1500, (323) 567-1122
James H. Hoffman
Treasurer , Director , Secretary
Twilight Home
James Hoffman
Director Medical Services
Martek Biosciences Corp
Drugs, Drug Proprietaries, and Druggists' Sun...
104 E Main St, Lansdale, PA 19446

Publications

Wikipedia

James Hoffman

View page

James Hoffman is a software engineer and inventor located in Alameda, California, who has worked in scientific visualization and was instrumental in producing the first ...

Wikipedia References

James Hoffman Photo 22

James Hoffman

Isbn (Books And Publications)

Prekindergarten Discoveries

View page
Author

James Hoffman

ISBN #

0513000976

Fabulous Principal Pie

View page
Author

James Hoffman

ISBN #

0887432662

Fabulous Principal Pie

View page
Author

James Hoffman

ISBN #

0887434274

The Beeginning

View page
Author

James Hoffman

ISBN #

0887435793

Pointing the Way

View page
Author

James Hoffman

ISBN #

0887435807

Roll Out the Barrel

View page
Author

James Hoffman

ISBN #

0887435815

The Garden Party

View page
Author

James Hoffman

ISBN #

0887435823

Test Success Reading & Math

View page
Author

James Hoffman

ISBN #

0887435564

Us Patents

Heteroaryl Amidines, Methylamidines And Guanidines, And Use Thereof As Protease Inhibitors

View page
US Patent:
6403633, Jun 11, 2002
Filed:
Apr 10, 2001
Appl. No.:
09/828783
Inventors:
Carl R. Illig - Phoenixville PA
Nalin L. Subasinghe - West Chester PA
James B. Hoffman - Ardmore PA
Kenneth J. Wilson - Exton PA
M. Jonathan Rudolph - Doylestown PA
Assignee:
3-Dimensional Pharmaceuticals, Inc. - Exton PA
International Classification:
A61K 3138
US Classification:
514438, 514365, 514336, 549 74, 548202, 5462804
Abstract:
The present invention is directed to compounds of Formula I: wherein X is O, S or NR and R -R , Y and Z are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof. Also described are methods for preparing the compounds of Formula I. The novel compounds of the present invention are potent inhibitors of proteases, especially trypsin-like serine proteases, such as chymotrypsin, trypsin, plasmin and urokinase. Certain of the compounds exhibit direct, selective inhibition of urokinase, or are intermediates useful for forming compounds having such activity.

Methods Of Treating C1S-Mediated Diseases And Conditions And Compositions Thereof

View page
US Patent:
6492403, Dec 10, 2002
Filed:
Feb 9, 2000
Appl. No.:
09/500783
Inventors:
Carl R. Illig - Phoenixville PA
Nalin L. Subasinghe - West Chester PA
James B. Hoffman - Ardmore PA
Kenneth J. Wilson - Exton PA
M. Jonathan Rudolph - Doylestown PA
Roger F. Bone - Bridgewater NJ
Scott L. Klein - Norristown PA
Troy L. Randle - Lindenwold NJ
Assignee:
3-Dimensional Pharmaceuticals, Inc. - Exton PA
International Classification:
A61K 31427
US Classification:
514365, 514438
Abstract:
Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R , R , R , R , X, Y and Z are defined in the specification.

Compounds And Compositions For Treating C1S-Mediated Diseases And Conditions

View page
US Patent:
6515002, Feb 4, 2003
Filed:
Sep 26, 2001
Appl. No.:
09/962304
Inventors:
Carl R. Illig - Phoenixville PA
Nalin L. Subasinghe - West Chester PA
James B. Hoffman - Ardmore PA
Kenneth J. Wilson - Exton PA
M. Jonathan Rudolph - Doylestown PA
Roger F. Bone - Bridgewater NJ
Scott L. Klein - Norristown PA
Troy L. Randle - Lindenwold NJ
Assignee:
3-Dimensional Pharmaceuticals, Inc. - Exton PA
International Classification:
C07D41718
US Classification:
514365, 548204
Abstract:
Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R , R , R , R , X, Y and Z are defined in the specification.

Heteroaryl Amidines, Methylamidines And Guanidines, And The Use Thereof As Protease Inhibitors

View page
US Patent:
6562840, May 13, 2003
Filed:
Feb 26, 2002
Appl. No.:
10/082127
Inventors:
Carl R. Illig - Phoenixville PA
Nalin L. Subasinghe - West Chester PA
James B. Hoffman - Ardmore PA
Kenneth J. Wilson - Exton PA
M. Jonathan Rudolph - Doylestown PA
Assignee:
3-Dimensional Pharmaceuticals, Inc. - Exton PA
International Classification:
A61K 3147
US Classification:
514312, 514438, 514256
Abstract:
The present invention is directed to compounds of Formula I: wherein X is O, S or NR and R âR , Y and Z are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof. Also described are methods for preparing the compounds of Formula I. The novel compounds of the present invention are potent inhibitors of proteases, especially trypsin-like serine proteases, such as chymotrypsin, trypsin, plasmin and urokinase. Certain of the compounds exhibit direct, selective inhibition of urokinase, or are intermediates useful for forming compounds having such activity.

Derivatives And Analogs Of N-Ethylquinolones And N-Ethylazaquinolones

View page
US Patent:
8071592, Dec 6, 2011
Filed:
Jul 18, 2007
Appl. No.:
12/374389
Inventors:
Lluis Ballell - Madrid, ES
David Barros - Madrid, ES
Gerald Brooks - Harlow, GB
Julia Castro Pichel - Madrid, ES
Steven Dabbs - Harlow, GB
Robert A Daines - Collegeville PA, US
David Thomas Davies - Harlow, GB
Jose Maria Fiandor Roman - Madrid, ES
Israil Pendrak - Collegeville PA, US
Modesto J Remuiñan Blanco - Madrid, ES
Jason Anthony Rossi - Collegeville PA, US
Ilaria Giordano - Harlow, GB
Alan Joseph Hennessy - Harlow, GB
James B Hoffman - Collegeville PA, US
Graham Elgin Jones - Harlow, GB
Timothy James Miles - Harlow, GB
Neil David Pearson - Harlow, GB
Assignee:
Glaxo Group Limited - Greenford, Middlesex
International Classification:
C07D 491/04
C07D 497/04
C07D 498/04
A61K 31/5383
A61K 31/519
US Classification:
5142305, 544105, 544279, 5142641
Abstract:
Bicyclic nitrogen containing compounds and their use as antibacterials.

Peptide Deformylase Inhibitors

View page
US Patent:
20130345120, Dec 26, 2013
Filed:
Mar 9, 2012
Appl. No.:
14/004105
Inventors:
Kelly M. Aubart - Collegeville PA, US
Andrew B. Benowitz - Collegeville PA, US
Yuhong Fang - Eagleville PA, US
James Hoffman - Ardmore PA, US
Joseph M. Karpinski - Stowe PA, US
Andrew Nicholson Knox - Philadelphia PA, US
Xiangmin Liao - Collegeville PA, US
Donghui Qin - Collegeville PA, US
Dongchuan Shi - Collegeville PA, US
Jared T. Spletstoser - Collegeville PA, US
Assignee:
Glaxosmithkline LLC - Philadelphia PA
International Classification:
C07K 5/078
C07D 401/12
C07D 231/06
C07D 403/12
US Classification:
514 26, 5462754, 514 2191, 514 24, 514 27, 546143, 548195, 548246, 5483561, 544238, 548143, 544131, 546162, 546122, 544329, 548261, 544336, 544317, 544408, 544277, 544324, 514275, 514341, 5483794, 514403, 5142365
Abstract:
The present invention relates to a compound of Formula (I):ora pharmaceutically acceptable salt thereof, corresponding pharmaceutical compositions, compound preparation and treatment methods directed to bacterial infections and inhibition of bacterial peptide deformylase (PDF) activity.

Heteroaryl Amidines, Methylamidines And Guanidines, Preparation Thereof, And Use Thereof As Protease Inhibitors

View page
US Patent:
62915142, Sep 18, 2001
Filed:
Aug 11, 1999
Appl. No.:
9/372748
Inventors:
Carl R. Illig - Phoenixville PA
Nalin L. Subasinghe - West Chester PA
James B. Hoffman - Ardmore PA
Kenneth J. Wilson - Exton PA
M. Jonathan Rudolph - Doylestown PA
Juan Jose Marugan - Exton PA
Assignee:
3-Dimensional Pharmaceuticals, Inc. - Exton PA
International Classification:
A61K 3138
A61K 31425
A61K 3147
A61K 3144
C07D33336
C07D40900
C07D27704
C07D21538
C07D41100
US Classification:
514447
Abstract:
The present invention is directed to compounds of Formula I: ##STR1## wherein X is O, S or NR. sup. 7 and R. sup. 1 -R. sup. 7, Y and Z are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof. Also described are methods for preparing the compounds of Formula I. The novel compounds of the present invention are potent inhibitors of proteases, especially trypsin-like serine proteases, such as chymotrypsin, trypsin, plasmin and urokinase. Certain of the compounds exhibit direct, selective inhibition of urokinase, or are intermediates useful for forming compounds having such activity.

Container Device For Separately Storing And Mixing Two Ingredients

View page
US Patent:
47310537, Mar 15, 1988
Filed:
Dec 23, 1986
Appl. No.:
6/945749
Inventors:
James P. Hoffman - Blue Bell PA
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61M 3700
US Classification:
604 89
Abstract:
The present invention relates to a container device that is useful for separately storing two ingredients, typically a solid ingredient and a liquid ingredient, and subsequently mixing the two ingredients within the container device. The container device is especially useful for the storage of a solid ingredient that can be degraded during storage, by moisture, and a liquid ingredient wherein, when such ingredients are mixed, the mixture is stable for only a short period of time.
James P Hoffman from Conshohocken, PA, age ~59 Get Report