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James Cardia Phones & Addresses

  • Franklin, MA
  • 415 Columbian St, South Weymouth, MA 02190
  • Weymouth, MA
  • 520 Washington St, Brighton, MA 02135 (617) 562-8058
  • Boston, MA
  • S Weymouth, MA
  • 520 Washington St #2, Brighton, MA 02135

Interests

expertise requests, reference requests, ...

Industries

Biotechnology

Resumes

Resumes

James Cardia Photo 1

Postdoctoral Fellow At Harvard University

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Location:
Greater Boston Area
Industry:
Biotechnology
Experience:
Harvard University (Educational Institution; 10,001 or more employees; Higher Education industry): Postdoctoral Fellow,  (-) 

Publications

Us Patents

Reduced Size Self-Delivering Rnai Compounds

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US Patent:
20120040459, Feb 16, 2012
Filed:
Sep 22, 2009
Appl. No.:
13/120342
Inventors:
Anastasia Khvorova - Westborough MA, US
William Salomon - Worcester MA, US
Joanne Kamens - Newton MA, US
Dmitry Samarsky - Westborough MA, US
Tod M. Woolf - Sudbury MA, US
James Cardia - Franklin MA, US
Assignee:
RXi Pharmaceuticals Corporation - Worcester MA
International Classification:
C12N 5/071
C12N 15/113
US Classification:
435375, 536 245
Abstract:
The present invention relates to RNAi constructs with minimal double-stranded regions, and their use in gene silencing. RNAi constructs associated with the invention include a double stranded region of 8-14 nucleotides and a variety of chemical modifications, and are highly effective in gene silencing.

Reduced Size Self-Delivering Rnai Compounds

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US Patent:
20130131141, May 23, 2013
Filed:
Mar 24, 2011
Appl. No.:
13/636728
Inventors:
Anastasia Khvorova - Westborough MA, US
William Salomon - Worcester MA, US
Joanne Kamens - Newton MA, US
Dmitry Samarsky - Westborough MA, US
Tod M. Woolf - Sudbury MA, US
James Cardia - Franklin MA, US
International Classification:
C12N 15/113
US Classification:
514 44 A, 536 245
Abstract:
The present invention relates to methods for in vivo administration of sd-rxRNA molecules.

Rna Interference In Ocular Indications

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US Patent:
20130131142, May 23, 2013
Filed:
Mar 24, 2011
Appl. No.:
13/636748
Inventors:
Lyn Libertine - Framingham MA, US
Anastasia Khvorova - Westborough MA, US
William Salomon - Worcester MA, US
Joanne Kamens - Newton MA, US
Dmitry Samarsky - Westborough MA, US
Tod M. Woolf - Sudury MA, US
James Cardia - Franklin MA, US
International Classification:
A61K 9/00
US Classification:
514 44 A, 536 245
Abstract:
The present invention relates to ocular administration of sd-rxRNA and rxRNAori molecules.

Reduced Size Self-Delivering Rnai Compounds

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US Patent:
20110263680, Oct 27, 2011
Filed:
Mar 23, 2011
Appl. No.:
13/069780
Inventors:
Anastasia Khvorova - Westborough MA, US
William Salomon - Worcester MA, US
Joanne Kamens - Newton MA, US
Dmitry Samarsky - Westborough MA, US
Tod M. Woolf - Sudbury MA, US
James Cardia - Franklin MA, US
Assignee:
RXi Pharmaceuticals Corporation - Worcester MA
International Classification:
A61K 31/713
C12N 5/00
A61P 35/00
A61P 27/02
A61P 29/00
A61P 37/06
A61P 9/00
C07H 21/02
A61P 31/12
US Classification:
514 44 A, 536 245, 435375
Abstract:
The present invention relates to RNAi constructs with minimal double-stranded regions, and their use in gene silencing. RNAi constructs associated with the invention include a double stranded region of 8-14 nucleotides and a variety of chemical modifications, and are highly effective in gene silencing. The RNAi constructs may be, for instance, miRNA constructs that are miRNA modulators.

Rna Interference In Dermal And Fibrotic Indications

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US Patent:
20210261968, Aug 26, 2021
Filed:
Jan 15, 2021
Appl. No.:
17/150934
Inventors:
- Marlborough MA, US
William Salomon - Worcester MA, US
Joanne Kamens - Newton MA, US
Dmitry Samarsky - Westborough MA, US
Tod M. Woolf - Sudbury MA, US
Pamela A. Pavco - Longmont CO, US
Lyn Libertine - Framingham MA, US
James Cardia - Franklin MA, US
Karen G. Bulock - Mendon MA, US
Assignee:
Phio Pharmaceuticals Corp. - Marlborough MA
International Classification:
C12N 15/113
Abstract:
The present invention relates to RNAi constructs with improved tissue and cellular uptake characteristics and methods of use of these compounds in dermal and fibrotic applications.

Reduced Size Self-Delivering Rnai Compounds

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US Patent:
20210147849, May 20, 2021
Filed:
Jul 21, 2020
Appl. No.:
16/934864
Inventors:
- Marlborough MA, US
William Salomon - Worcester MA, US
Joanne Kamens - Newton MA, US
Dmitry Samarsky - Westborough MA, US
Tod M. Woolf - Sudbury MA, US
James Cardia - Franklin MA, US
Assignee:
Phio Pharmaceuticals Corp. - Marlborough MA
International Classification:
C12N 15/113
C12N 15/11
Abstract:
The present invention relates to RNAi constructs with minimal double-stranded regions, and their use in gene silencing. RNAi constructs associated with the invention include a double stranded region of 8-14 nucleotides and a variety of chemical modifications, and are highly effective in gene silencing.

Rna Interference In Ocular Indications

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US Patent:
20210062195, Mar 4, 2021
Filed:
May 12, 2020
Appl. No.:
15/930377
Inventors:
- Marlborough MA, US
Anastasia Khvorova - Westborough MA, US
William Salomon - Worcester MA, US
Joanne Kamens - Newton MA, US
Dmitry Samarsky - Westborough MA, US
Tod M. Woolf - Sudbury MA, US
James Cardia - Franklin MA, US
Pamela A. Pavco - Longmont CO, US
Assignee:
Phio Pharmaceuticals Corp. - Marlborough MA
International Classification:
C12N 15/113
A61K 9/00
A61K 31/713
A61K 45/06
A61K 47/54
Abstract:
The present invention relates to ocular administration of sd-rxRNA and rxRNAori molecules.

Reduced Size Self-Delivering Rnai Compounds

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US Patent:
20200002701, Jan 2, 2020
Filed:
Feb 7, 2019
Appl. No.:
16/270524
Inventors:
- Marlborough MA, US
William Salomon - Worcester MA, US
Joanne Kamens - Newton MA, US
Dmitry Samarsky - Westborough MA, US
Tod M. Woolf - Sudbury MA, US
James Cardia - Franklin MA, US
Assignee:
Phio Pharmaceuticals Corp. - Marlborough MA
International Classification:
C12N 15/113
C07H 21/02
C12N 15/11
Abstract:
The present invention relates to methods for in vivo administration of sd-rxRNA molecules.
James P Cardia from Franklin, MA, age ~46 Get Report