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Isaac S Carrico

from Stony Brook, NY
Age ~50
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Also known as:
Isaac Sheridan Carrico, Issac Carrico
Related to:
Margaret Ellen Carrico, 55Trey CarricoSusanne Carrico, 89Frank Carrico, 53Charles Carrico
Connected to:
Allen W Carrico, 51Ashley M Carrico, 35Christy Carrico, 61Cristina M Carrico, 38Danny Carrico, 58Earl A Carrico, 73Edward D Carrico, 65Evan J Carrico, 34Gina A Carrico, 62Jamie L Carrico, 48

Isaac Carrico Phones & Addresses

  • Stony Brook, NY
  • Port Jefferson, NY
  • Durham, NC
  • Berkeley, CA
  • Pasadena, CA
  • Los Angeles, CA
  • Santa Barbara, CA
  • 4 North Rd, Stony Brook, NY 11790

Work

Position: Clerical/White Collar

Education

Degree: Associate degree or higher

Emails

i***[email protected]

Publications

Us Patents

Aldehyde Tags, Uses Thereof In Site-Specific Protein Modification

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US Patent:
7985783, Jul 26, 2011
Filed:
Sep 18, 2007
Appl. No.:
11/857385
Inventors:
Isaac S. Carrico - Berkeley CA, US
Brian L. Carlson - Richmond CA, US
Peng Wu - Berkeley CA, US
Carolyn Bertozzi - Berkeley CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61L 33/00
C07H 21/02
US Classification:
522 87, 536 231
Abstract:
The invention features compositions and methods for site-specific modification of proteins by incorporation of an aldehyde tag. Enzymatic modification at a sulfatase motif of the aldehyde tag through action of a formylglycine generating enzyme (FGE) generates a formylglycine (FGly) residue. The aldehyde moiety of FGly residue can be exploited as a chemical handle for site-specific attachment of a moiety of interest to a polypeptide.

Aldehyde Tags, Uses Thereof In Site-Specific Protein Modification

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US Patent:
8097701, Jan 17, 2012
Filed:
Jun 17, 2011
Appl. No.:
13/163565
Inventors:
Isaac S. Carrico - Stony Brook NY, US
Brian L. Carlson - Richmond CA, US
Peng Wu - Berkeley CA, US
Carolyn Ruth Bertozzi - Berkeley CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C07K 1/00
C07K 16/00
A61L 33/00
US Classification:
530350, 5303871, 522 87
Abstract:
The invention features compositions and methods for site-specific modification of proteins by incorporation of an aldehyde tag. Enzymatic modification at a sulfatase motif of the aldehyde tag through action of a formylglycine generating enzyme (FGE) generates a formylglycine (FGly) residue. The aldehyde moiety of FGly residue can be exploited as a chemical handle for site-specific attachment of a moiety of interest to a polypeptide.

Aldehyde Tags, Uses Thereof In Site-Specific Protein Modification

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US Patent:
8349910, Jan 8, 2013
Filed:
Jun 17, 2011
Appl. No.:
13/163574
Inventors:
Isaac S. Carrico - Stony Brook NY, US
Brian L. Carlson - Richmond CA, US
Peng Wu - Berkeley CA, US
Carolyn Ruth Bertozzi - Berkeley CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61L 33/00
C07K 1/00
C12N 15/00
US Classification:
522 87, 530350, 4353201
Abstract:
The invention features compositions and methods for site-specific modification of proteins by incorporation of an aldehyde tag. Enzymatic modification at a sulfatase motif of the aldehyde tag through action of a formylglycine generating enzyme (FGE) generates a formylglycine (FGly) residue. The aldehyde moiety of FGly residue can be exploited as a chemical handle for site-specific attachment of a moiety of interest to a polypeptide.

Computational Method For Designing Enzymes For Incorporation Of Non Natural Amino Acids Into Proteins

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US Patent:
20040053390, Mar 18, 2004
Filed:
Feb 27, 2003
Appl. No.:
10/375298
Inventors:
Deepshikha Datta - South Pasadena CA, US
Pin Wang - Pasadena CA, US
Isaac Carrico - Pasadena CA, US
Stephen Mayo - Pasadena CA, US
David Tirrell - Pasadena CA, US
Assignee:
California Institute of Technology - Pasadena CA
International Classification:
G06F019/00
G01N033/48
G01N033/50
C12N015/00
C12N009/22
C12P021/02
C12N005/06
US Classification:
435/199000, 702/019000, 435/069100, 435/320100, 435/325000
Abstract:
The instant invention provides methods, reagents, and computational tools for designing non-natural substrate analogs for enzymes, especially for designing unnatural amino acid analogs for aminoacyl tRNA Synthetases (AARSs), such as the Phe tRNA Synthetase. The instant invention also provides methods to incorporate unnatural amino acid analogs, especially those with interesting functional groups, into protein products to generate proteins of modified or novel functions.

Computational Method For Designing Enzymes For Incorporation Of Amino Acid Analogs Into Proteins

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US Patent:
20060177865, Aug 10, 2006
Filed:
Apr 7, 2006
Appl. No.:
11/399957
Inventors:
Deepshikha Datta - South Pasadena CA, US
Pin Wang - Pasadena CA, US
Isaac Carrico - Pasadena CA, US
Stephen Mayo - Pasadena CA, US
David Tirrell - Pasadena CA, US
Assignee:
California Institute of Technology - Pasadena CA
International Classification:
C12Q 1/68
G06F 19/00
C12N 9/22
US Classification:
435006000, 702020000, 435199000
Abstract:
The instant invention provides methods, reagents, and computational tools for designing non-natural substrate analogs for enzymes, especially for designing unnatural amino acid analogs for aminoacyl tRNA Synthetases (AARSs), such as the Phe tRNA Synthetase. The instant invention also provides methods to incorporate unnatural amino acid analogs, especially those with interesting functional groups, into protein products to generate proteins of modified or novel functions.

Viruses Modified With Unnatural Moieties And Methods Of Use Thereof

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US Patent:
20140140962, May 22, 2014
Filed:
Apr 26, 2012
Appl. No.:
14/114052
Inventors:
Isaac Sheridan Carrico - Stony Brook NY, US
Banerjee Partha - Baltimore MD, US
Patrick Hearing - St. James NY, US
Oum Yoon Hyeun - Atlanta GA, US
Assignee:
The Research Foundation of State University of New York - Albany NY
International Classification:
C12N 7/00
US Classification:
424 936, 4352351
Abstract:
The invention provides compositions and methods for making and using modified viruses, including infectious viruses, having an external surface linked to at least one heterologous unnatural moiety that is exemplified by unnatural amino acid and unnatural saccharide. The unnatural moiety that is linked to the invention's modified viruses is optionally further linked to a molecule of interest (such as probe, cytotoxin, therapeutic molecule, antibody, affibody, epitope, etc. The invention's compositions and methods for use in, for example, diagnostic applications and therapeutic applications such as gene therapy, oncolytic therapy, and/or vaccine therapy.
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Isaac S Carrico from Stony Brook, NY, age ~50 Get Report