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Howard Kallender Phones & Addresses

  • 572 Barrett Ave, Haverford, PA 19041
  • Wayne, PA
  • King of Prussia, PA
  • Collegeville, PA
  • Montgomery, PA
  • 409 Eagle Rd, Wayne, PA 19087

Work

Company: Gsk Position: Clinical development director

Education

Degree: Associate degree or higher

Emails

Industries

Pharmaceuticals

Resumes

Resumes

Howard Kallender Photo 1

Clinical Development Director

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Location:
Haverford, PA
Industry:
Pharmaceuticals
Work:
Gsk
Clinical Development Director

Publications

Us Patents

Gidb

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US Patent:
6353093, Mar 5, 2002
Filed:
Aug 31, 2000
Appl. No.:
09/651873
Inventors:
Martin K R Burnham - Barto PA
Howard Kallender - King of Prussia PA
Anna Lisa Lenox - Doylestown PA
Judith Ward - Dorking, GB
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07K 100
US Classification:
530350, 4241851, 4241901, 4241921, 4242341
Abstract:
The invention provides gidB polypeptides and polynucleotides encoding gidB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gidB polypeptides to screen for antibacterial compounds.

Gidb From Staphylococcus Aureus

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US Patent:
6403334, Jun 11, 2002
Filed:
Dec 16, 1998
Appl. No.:
09/212236
Inventors:
Howard Kallender - King of Prussia PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
SmithKline Beecham p.l.c.
International Classification:
C12P 2106
US Classification:
435 691, 435 693, 435 701, 435 711, 435 712, 4352523, 43525411, 4353201, 435325, 536 237, 935 6, 935 12, 935 22, 935 66, 935109
Abstract:
The invention provides gidB polypeptides and DNA (RNA) encoding gidB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gidB polypeptides to screen for antibacterial compounds.

Ratc From Streptococcus Pneumoniae

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US Patent:
6432703, Aug 13, 2002
Filed:
Aug 27, 1998
Appl. No.:
09/140580
Inventors:
Howard Kallender - King of Prussia PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C12N 500
US Classification:
435325, 4353201, 536 237
Abstract:
The invention provides ratC polypeptides and polynucleotides encoding ratC polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ratC polypeptides to screen for antibacterial compounds.

Bira From Staphylococcus Aureus

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US Patent:
6448038, Sep 10, 2002
Filed:
Jan 26, 1999
Appl. No.:
09/237119
Inventors:
Jianzhong Huang - Schwenksville PA
Howard Kallender - Wayne PA
Damien McDevitt - Berwyn PA
Stephanie Van Horn - Pottstown PA
Daniel R Sylvester - Collegeville PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C12P 2106
US Classification:
435 691, 435 693, 435 701, 435 711, 4353201, 435325, 43525411, 4352523, 536 237
Abstract:
The invention provides birA polypeptides and polynucleotides encoding birA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing birA polypeptides to screen for antibacterial compounds.

Ef-Tu

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US Patent:
6451556, Sep 17, 2002
Filed:
Dec 21, 1998
Appl. No.:
09/218197
Inventors:
Howard Kallender - Wayne PA
Stephanie Van Horn - Pottstown PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C12P 2106
US Classification:
435 691, 536 232, 536 237, 4353201, 435325
Abstract:
The invention provides EF-Tu polypeptides and polynucleotides encoding EF-Tu polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing EF-Tu polypeptides to screen for antibacterial compounds.

Fabz From Staphylococcus Aureus

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US Patent:
6489139, Dec 3, 2002
Filed:
Jun 24, 1999
Appl. No.:
09/339614
Inventors:
Howard Kallender - Wayne PA
John T. Lonsdale - Exton PA
Stephanie Van Horn - Pottstown PA
Patrick V. Warren - Coatsville PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C12N 1500
US Classification:
435 691, 4352523, 435325, 435471, 435455, 4353201, 536 231, 536 232, 536 234, 536 237
Abstract:
The invention provides fabZ polypeptides and polynucleotides encoding fabZ polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing fabZ polypeptides to screen for antibacterial compounds.

High Throughput Screening Method For Biological Agents Affecting Fatty Acid Biosynthesis

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US Patent:
6951729, Oct 4, 2005
Filed:
Oct 26, 2000
Appl. No.:
10/089019
Inventors:
Howard Kallender - Wayne PA, US
John T Lonsdale - Exton PA, US
Assignee:
Affinium Pharmaceuticals, Inc. - Toronto
International Classification:
C12Q001/48
US Classification:
435 15, 435 4
Abstract:
Provided is a screening method for compounds affecting fatty acid biosynthesis, the method comprising: providing a reaction mixture comprising: an acyl carrier moiety or enzymes and precursors sufficient to generate the acyl carrier moiety; a bacterial enzymatic pathway comprising at least two consecutively acting enzymes selected from the group consisting of: malonyl-CoA:ACP transacylase, beta-ketoacyl-ACP synthase III, NADPH dependent beta-ketoacyl-ACP reductase, beta-hydroxylacyl-ACP dehydrase and enoyl-ACP reductase; and substrates and cofactors required for the operation of the enzymes; contacting the reaction mixture with a prospective bioactive agent; conducting a high throughput measurement of the activity of the enzymatic pathway; and determining if the contacting altered the activity of the enzymatic pathway.

Whole Cell Assay

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US Patent:
20020115217, Aug 22, 2002
Filed:
Oct 17, 2001
Appl. No.:
09/981121
Inventors:
Frank Fan - Collegeville PA, US
Yinduo Ji - Collegeville PA, US
Howard Kallender - Collegeville PA, US
Tong Li - Collegeville PA, US
Damien McDevitt - Collegeville PA, US
Assignee:
SmithKline Beecham Corporation
International Classification:
C12Q001/00
C12Q001/68
C12N015/87
US Classification:
435/455000, 435/004000, 435/006000
Abstract:
This invention relates to newly developed methods for discovering therapeutic compounds using a cell-based assay system. This invention also relates to compositions of matter useful in carrying out the methods of the invention as well as therapeutic compounds developed using such methods.
Howard H Kallender from Haverford, PA, age ~60 Get Report